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Take heart, it's all good news
New evidence uncovered by researchers in Tayside and Bristol has shown wider benefits of cholesterol lowering drugs for large sections of the public, including women and the elderly. view more (2005-03-30)
Three-year SAPPHIRE and US carotid feasibility trials demonstrate durability of carotid stenting
Preliminary three-year data from the SAPPHIRE and final three-year data from the U.S. Carotid Feasibility Study (USFS) presented at the 2005 Transcatheter Cardiovascular Therapeutics meeting, demonstrate the long-term durability of carotid artery stenting (CAS) for the prevention of stroke versus carotid endarterectomy (CEA) in high risk surgical... view more... (2005-10-19)
Rockhampton part of worldwide fight against respiratory infections
The new Capricornia Centre for Mucosal Immunology has been established under the leadership of Professor Jennelle Kyd, whose research on immunity and vaccines is recognized internationally. view more (2006-12-07)
Researchers Ask European Parliament To Repeal Clinical Trials Directive
European health-care researchers have launched a campaign calling on the European Parliament and Commission to repeal their Directive (EC/2001/20) on Good Clinical Practice. Implementation of this directive, which is due to come into effect in all Member States by next May, will, according to these investigators, place enormous, and possibly... view more... (2004-01-12)
Short-term hemofiltration is cost-effective for severe acute pancreatitis
Early nasogastric enteral nutrition is a breakthrough in the management of severe acute pancreatitis. From meta-analysis based on current available clinical studies early nasogastric enteral nutrition appeared effective and safe in clinical practice. view more (2007-10-15)
Meta-analyses of global trials finds in favor of aromatase inhibitors
Two separate meta-analyses of clinical trials from around the world that tested tamoxifen against aromatase inhibitor drugs in postmenopausal women with early breast cancer have each reached the same conclusion: aromatase inhibitors are more effective in preventing breast cancer from coming back. view more (2008-12-12)
Study finds flaws in cancer clinical trials
Cancer research and drug development are yielding more sophisticated candidate therapies, but investigators' methods to test them haven't kept pace, according to researchers at Memorial Sloan-Kettering Cancer Center. view more (2007-02-02)
Cancer Research UK supports additional TroVax phase II trial in colorectal cancer
Oxford BioMedica announced today that Cancer Research UK (CRUK) has agreed to conduct and sponsor an open label Phase II trial with Oxford BioMedica's leading cancer immunotherapy product, TroVax®, in colorectal cancer patients who have liver metastases. The decision by CRUK follows extensive review of the successful Phase I/II data of TroVax... view more... (2003-08-28)
New criteria for measuring tumor size and progression will help ease workloads in clinical trials
The first, formal revision of specific guidelines, known as RECIST, used by clinicians to measure tumour size and response to treatment, has been published today (Tuesday 20 January) in a special issue of the European Journal of Cancer. view more (2009-01-20)
Herceptin gives disappointing results in lung cancer trial
Trastuzumab (Herceptin) - a treatment that has increased survival in many breast cancer patients - has failed to live up to hopes that it might also help lung cancer patients. view more (2004-01-08)
New flu drugs are effective but have important limitations
Evidence suggests that two new antiviral drugs (oseltamivir and zanamivir) are effective for treating and preventing flu, but more research is needed to clarify who will benefit most from treatment, concludes a study in this week’s BMJ. view more (2003-06-04)
Modest Survival Benefit From Chemotherapy For Patients With Glioma Brain Tumours (p 1011)
Chemotherapy in addition to radiotherapy could have a modest survival benefit for the treatment of high-grade glioma, a severe form of brain cancer, conclude authors of a study in this week's issue of THE LANCET. Malignant gliomas are among the most devastating of cancers. They frequently result in profound and progressive disability, which often... view more... (2002-03-20)
Turning green gunk to gold, anti-cancer gold
Combining synthetic chemistry techniques with a knowledge of the properties and actions of enzymes, scientists have been able to produce an exciting class of anti-cancer drugs originally isolated from blue-green algae. view more (2007-01-10)
Worldwide clinical trials for new technique for early detection of eye disease
A unique new non-invasive technique for high resolution optical imaging of the eye is receiving global acclaim. The technique, pioneered by the University of Kent, is funded by the Toronto-based company, Ophthalmic Technology Inc (OTI). The University's Applied Optics Group is currently working with university hospitals in New York (USA), Osaka... view more... (2004-10-12)
NIAID set to launch clinical trials to test 2009 H1N1 influenza vaccine candidates
Scientists in a network of medical research institutions across the United States are set to begin a series of clinical trials to gather critical data about influenza vaccines, including two candidate H1N1 flu vaccines. view more (2009-07-23)
Making traumatized patients relive their trauma is useless and caused further suffering
Debriefing (making patients relive their traumatic experience) is thought to be key psychotherapeutic strategy for patients who underwent psychological traumas. Yet a meta-analysis just published in Psychotherapy and Psychosomatics by British researchers challenges the usefulness of this approach. Single-session psychological interventions such... view more... (2003-06-17)
Blood Pressure Drug Combination Reduces Heart Attack Deaths
Thousands of patients with high blood pressure could benefit from changing their drug treatment regimen to reduce their risk of cardiac death. view more (2008-09-17)
Blood cholesterol levels predict risk of heart disease due to hormone therapy
A new analysis of a subgroup of participants in the Women's Health Initiative (WHI) hormone therapy clinical trials suggests that healthy, postmenopausal women whose blood cholesterol levels are normal or lower are not at increased, short-term risk for heart attack when taking hormone therapy. view more (2008-05-27)
Positive study results for methylphenidate transdermal system
Shire announced at a major medical meeting in Toronto, Canada, that its investigational methylphenidate transdermal system (MTS) demonstrated statistically significant reductions in the symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD) and was generally well tolerated in patients aged 6 to 12 in two clinical trials. view more (2005-10-24)
Low-carbohydrate diets appear effective, but may raise cholesterol levels
A synthesis of data from five previous clinical trials suggests that both low-fat and low-carbohydrate diets appear to be effective for weight loss up to one year, but low-carbohydrate diets may be linked to higher overall and LDL or "bad" cholesterol levels. view more (2006-02-14)
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