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Clinical Trials Current Events | Clinical Trials News | 9

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Review finds conflicts of interest in many cancer studies
A new analysis finds that a considerable number of clinical cancer studies published in respected medical journals have financial connections to pharmaceutical companies.   view more (2009-05-11)

Swedish Trials Suggest Modest Benefit For Screening Mammography (PP 904, 909)
New data with longer follow-up from four Swedish trials published in this week's issue of THE LANCET suggests there may be a modest benefit from screening mammography for women aged 55 years or over. Considerable debate surrounds the issue of screening mammography and its possible benefits. A research letter by Ole Olsen and Peter Gotzsche (Lancet... view more... (2002-03-13)

Serendipity versus planning-cancer drugs of the future?
Delegates at the European Breast Cancer Conference (EBCC-5) were given two examples of promising new drugs to watch in the future-raloxifene and lapatinib.   view more (2006-03-27)

Biochip for detection of inflammatory bowel disease
At the III International Symposium on Advanced Therapy for Chronic Inflammatory Bowel Disease, held in Madrid, the biotechnological company, Progenika, presented a DNA-chip the purpose of which is the optimisation of the diagnosis, prognosis and treatment of patients with inflammatory bowel disease (Crohn's disease and Ulcerous Colitis).   view more (2005-01-26)

Clinical Trials Present Better Alternatives for Dialysis Patients
Having a healthy kidney is worth a billion dollars. But an unhealthy kidney costs more-about $16 billion more, according to Prabir Roy-Chaudhury, MD, PhD, associate professor in the division of nephrology and hypertension at the University of Cincinnati (UC).   view more (2007-09-13)

Combined Chemotherapy and Radiotherapy for Cervical Cancer Could Increase Survival (p 781)
A systematic review of randomised trials in the past two decades published in this week’s issue of THE LANCET concludes that women given concurrent chemotherapy and radiotherapy for cervical cancer could have an increased survival-rate of 12% compared with patients treated with radiotherapy alone. Cervical cancer is the second most common... view more... (2001-09-05)

Early use of statins after coronary syndromes does not reduce risk of heart attack, stroke or death
Beginning use of statins within 14 days of acute coronary syndromes (such as heart attack or unstable angina) does not decrease the risk of death, heart attack, or stroke, for up to 4 months, based on a meta-analysis of previously published studies.   view more (2006-05-03)

Genetic tests advertised directly to the consumer
Genetic testing services have recently begun to be advertised directly to the patient, and the results of the consumers' response can affect public health, as well as the future adoption of pharmacogenetic/genomic testing.   view more (2009-07-22)

The disease markers that will aid arthritis research
A combination of biochemical and MRI markers will allow improved measurement of osteoarthritis (OA) progression.   view more (2009-07-24)

Engineered pig stem cells bridge the mouse-human gap
The discovery that adult skin cells can be 'reprogrammed' to behave like stem cells has been a major scientific boon, providing a way to tap the potential of embryonic stem cells without the associated ethical quandaries.   view more (2009-06-04)

Media invitation: First Annual EDCTP Forum
Enrico Garaci, President of the Istituto Superiore di Sanit'  (ISS), Stefano Vella, Director of Drug Department (ISS), together with Piero Olliaro, Executive Director of the European and Developing Countries Clinical Trials Partnership (EDCTP) and Pascoal Mocumbi, High Representative of the EDCTP and ex Prime Minister of Mozambico, invite members... view more... (2004-09-27)

Use of some antioxidant supplements may increase mortality risk
Contradicting claims of disease prevention, an analysis of previous studies indicates that the antioxidant supplements beta carotene, vitamin A, and vitamin E may increase the risk of death.   view more (2007-02-28)

MAJOR TRIAL WILL LOOK AT BEST WAYS TO FEED STROKE PATIENTS
Dr Martin Dennis, Reader in Stroke Medicine and FOOD Trial Clinical Co-ordinator at the Neurosciences Trials Unit, explains: "Stroke affects approximately 15,000 people in Scotland every year and accounts for about 5% of NHS resources. Currently, there are no definitive recommendations for feeding a patient with stroke, although one of the... view more... (1999-06-21)

New study re-evaluates cardiovascular risks of anti-inflammatory drugs
High doses of some traditional non-steroidal anti-inflammatory drugs (NSAIDS) are associated with similar cardiovascular risks as the new generation of anti-inflammatory drugs known as COX 2 inhibitors (like Vioxx ®), finds a study in this week's BMJ.   view more (2006-06-02)

Warning over nitric oxide for lung injury patients
Use of nitric oxide in patients with acute lung injury does not improve survival and may cause harm, warn researchers in a study published on bmj.com today.   view more (2007-03-23)

Statins have neutral effect on risk of cancer
The cholesterol-lowering medications called statins do not appear to reduce the incidence of cancer or cancer deaths.   view more (2006-01-04)

Aspirin Does Not Reduce Effectiveness Of ACE Inhibitors
A systematic review in this week's issue of THE LANCET provides clarification for the debate about the use of angiotensin-converting-enzyme (ACE) inhibitors in combination with aspirin for the treatment of cardiovascular disease-combination therapy does not reduce the effect of ACE inhibition. Previous research has suggested that ACE inhibitors... view more... (2002-10-02)

Anthracyclines improve survival in HER2-positive breast cancer patients
Treatment with the class of chemotherapy drugs called anthracyclines improves survival in women with HER2-positive breast cancer who have previously had surgery, but it may not offer any benefit for women with HER2-negative tumors.   view more (2007-12-26)

U of MN uses robotic surgery techniques in cardiac cell therapy research
Researchers at the University of Minnesota were successful in using robotic surgery to deliver stem cell treatment to damaged heart tissue in pigs.   view more (2006-08-01)

Most popular websites not necessarily of highest quality
The more popular websites providing information about breast cancer are not necessarily of higher quality, concludes a study in this week's BMJ.   view more (2002-03-06)
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