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Strokes may be associated with cocaine and amphetamine abuse
The use of stimulant drugs, including cocaine and amphetamines, may be linked to a higher risk for stroke, according to a report in the April issue of Archives of General Psychiatry, one of the JAMA/Archives journals.   view more (2007-04-03)

Animal research suggests new strategy for treating cocaine addiction
New research in monkeys suggests the feasibility of treating cocaine addiction with a "replacement" drug that mimics the effects of cocaine but has less potential for abuse - similar to the way nicotine and heroin addictions are treated.   view more (2008-04-07)

Research offers new approach to developing treatments for cocaine and amphetamine addiction
The study shows that highly addictive drugs, like cocaine and amphetamine, require a neurotransmitter called CART (Cocaine- and Amphetamine-Regulated Transcript) peptides to produce their maximal effects.   view more (2005-09-29)

Insulin signaling and amphetamines
Abuse of psychostimulants such as amphetamine remains a serious public health concern. Amphetamines mediate their behavioral effects by stimulating dopaminergic signaling throughout reward circuits of the brain.   view more (2007-10-16)

Cocaine Use Related to Level of Education Achieved
The decreased use of cocaine in the United States over the last 20 years mostly occurred among the highly educated, while cocaine use among non-high school graduates remained constant, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health.   view more (2007-08-30)

Cicardian system suffers and protects from prenatal cocaine exposure
Researchers from Boston University School of Medicine (BUSM) have shown that prenatal cocaine exposure in zebrafish (which share the majority of the same genes with humans) can alter neuronal development and acutely dysregulate the expression of circadian genes and those affecting melatonin signaling, growth and neurotransmission.   view more (2007-07-11)

Study finds link between amphetamine abuse and heart attacks in young adults
Young adults who abuse amphetamines may be at greater risk of suffering a heart attack, UT Southwestern Medical Center researchers have found.   view more (2008-06-04)

Prenatal cocaine's lasting cellular effects
Although the "crack baby" hysteria of the 1980s was greatly exaggerated, cocaine use during pregnancy can cause subtle but disabling cognitive impairments — attention deficits, learning disabilities and emotional problems.   view more (2007-01-15)

Cocaine-linked genes enhance behavioral effects of addiction
New research sheds light on how cocaine regulates gene expression in a crucial reward region of the brain to elicit long-lasting changes in behavior.   view more (2009-05-14)

Cocaine: Perceived as a reward by the brain?
Cocaine is one of the oldest drugs known to humans, and its abuse has become widespread since the end of the 19th century.   view more (2009-05-20)

Insulin's brain impact links drugs and diabetes
Insulin, long known as an important regulator of blood glucose levels, now has a newly appreciated role in the brain.   view more (2007-10-17)

Cocaine and heroin harm placenta
Cocaine and heroin increase permeability of the placenta. Researchers writing in BioMed Central's open access journal Reproductive Biology and Endocrinology have shown that exposure to the drugs causes an increase in the passage of some chemicals into the fetus.   view more (2009-06-11)

Recreational cocaine use may impair inhibitory control
The recreational use of cocaine has rapidly increased in many European countries over the past few years.   view more (2007-11-07)

Comparison of cocaine and methamphetamine 'highs' finds differences in onset, pattern and duration
Investigators at the Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA examining responses to cocaine and methamphetamine use find distinct differences in onset, pattern and duration.   view more (2005-08-25)

Research reveals molecular fingerprint of cocaine addiction
The first large-scale analysis of proteins in the brains of monkeys addicted to cocaine reveals new information on how long-term cocaine use changes the amount and activity of various proteins affecting brain function.   view more (2008-05-28)

Shire bioequivalence study results of SPD465, investigational drug for adults with ADHD
Shire plc (LSE: SHP, NASDAQ: SHPGY, TSX: SHQ) announced today that a single once-daily morning dose of the investigational amphetamine compound SPD465, extended release triple-bead mixed amphetamine salts, designed to reduce symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD) in adults for up to 16 hours, was bioequivalent to a dose of... view more... (2006-11-17)

Delving deeper into the machinery of cocaine addiction
Researchers are now understanding in greater detail the molecular machinery underlying the short-term brain changes that produce the high of cocaine, as well as the longer-term changes behind addiction. Their findings offer hope for targeted drugs that can short-circuit that addiction machinery.   view more (2005-10-20)

New study: Up to 90 percent of US paper money contains traces of cocaine
You probably have cocaine in your wallet, purse, or pocket. Sound unlikely or outrageous? Think again! In what researchers describe as the largest, most comprehensive analysis to date of cocaine contamination in banknotes, scientists are reporting that cocaine is present in up to 90 percent of paper money in the United States, particularly in... view more... (2009-08-17)

New treatment effective in counteracting cocaine-induced symptoms
UT Southwestern Medical Center researchers have discovered a treatment that counteracts the effects of cocaine on the human cardiovascular system, including lowering the elevated heart rate and blood pressure often found in cocaine users.   view more (2007-08-13)

PET imaging confirms link between receptor levels and cocaine abuse
Using positron emission tomography (PET), researchers have established a firm connection between a particular brain chemistry trait and the tendency of an individual to abuse cocaine and possibly become addicted, suggesting potential treatment options.   view more (2006-07-12)
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