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Screening for colorectal cancer should start at age 50
New estimates of the lifetime risk of developing colorectal cancer, published in the Journal of Medical Screening, suggest that screening should start at age 50 or 55 in the general population. For individuals with a family history of colorectal cancer, screening is recommended from age 40-44.... view more (2000-11-20)

Human Cytomegalovirus May Be Involved In Colorectal Cancer (p 1557)
Preliminary findings of a study in this week's issue of THE LANCET suggest that a common human virus may play a part in the cellular processes involved in the development of colorectal cancer. Colorectal cancer is the second most frequent cause of death from cancer in many developed countries;... view more (2002-11-13)

New evidence finds no association between coffee consumption and risk of colorectal cancer
There is no association between coffee consumption and risk of colorectal cancer, finds new evidence in Gut, despite previous studies suggesting a protective effect of coffee consumption. This presumption may be premature, report the authors. Paul Terry and colleagues examined data from over 61,... view more (2001-06-14)

Low-fat diet does not reduce risk of colorectal cancer
In an article in the February 8 JAMA, Shirley A. A. Beresford, Ph.D., of the University of Washington, Seattle, and colleagues with the Women's Health Initiative (a study which included nearly 50,000 women) analyzed data from the WHI Dietary Modification Trial to determine the effect of a low-fat... view more (2006-02-08)

Cancer Research UK supports additional TroVax phase II trial in colorectal cancer
Oxford BioMedica announced today that Cancer Research UK (CRUK) has agreed to conduct and sponsor an open label Phase II trial with Oxford BioMedica's leading cancer immunotherapy product, TroVax®, in colorectal cancer patients who have liver metastases. The decision by CRUK follows extensive... view more (2003-08-28)

Cholesterol-lowering drugs not associated with reduced colorectal cancer risk
Use of cholesterol reducing drugs is not associated with a reduced risk of colorectal cancer, according to a study in the January 4 issue of the Journal of the National Cancer Institute .   view more (2006-01-04)

BREAST CANCER DOES NOT INCREASE RISK OF COLORECTAL CANCER
Women with a history of breast cancer are not at an increased risk of colorectal cancer, conclude authors of a study published in this week's issue of THE LANCET. A history of breast cancer has been reported as a risk factor for colorectal cancer in women. However, in view of the ambiguous nature... view more (2001-03-15)

DNA test shows promise for identifying patients with colorectal cancer (p 1283)
Testing for DNA changes in stools might provide a new, accurate, and less invasive way to screen patients for colorectal cancer, conclude the authors of a research letter in this week's issue of THE LANCET. Colorectal cancer is one of the most common cancers in the industrialised world, and early... view more (2004-04-14)

Keyhole Surgery For Colorectal Cancer Offers Same Prognosis As Conventional Surgery (p 1187)
Laparoscopy ('keyhole surgery') for colorectal cancer could be the future treatment of choice after results of a study from Hong Kong in this week's issue of THE LANCET show how it is associated with a similar 5-year survival outcome and more favourable recovery time than conventional surgery.... view more (2004-04-07)

NO COMMON CAUSE LINKING INFLAMMATORY BOWEL DISEASE AND COLORECTAL CANCER (pp 246, 262)
Research published in this week's issue of THE LANCET does not support the theory that there may be a single genetic cause for inflammatory bowel disease (IBD) and colorectal cancer. The causes of IBD and colorectal cancer (which occurs more often in people with IBD) are unknown. Some researchers... view more (2001-01-24)

Scientists discover major genetic cause of colorectal cancer
About one-third of colorectal cancers are inherited, but the genetic cause of most of these cancers is unknown. The genes linked to colorectal cancer account for less than 5 percent of all cases.   view more (2008-08-15)

A search for biomarkers for early detection of colorectal cancer
Researchers at the Zhejiang University, Hangzhou have discovered that mimecan and Thioredoxin Domain-Containing Protein 5 (TXNDC5) were differentially expressed in colorectal adenoma.   view more (2007-09-25)

Obesity strongest risk factor for colorectal cancer among women; greater than smoking
Research presented at the 72nd Annual Scientific Meeting of the American College of Gastroenterology found that obesity, among other important risk factors, was the strongest risk factor for colorectal cancer in women.   view more (2007-10-15)

Increased hepcidin expression: A novel oncogenic signalling mechanism
Historically anaemia, which is associated with colorectal cancer, has been attributed to blood loss. Previous studies have elegantly shown that the anti-microbial peptide hepcidin can also induce anaemia as a consequence of infection and or inflammation.   view more (2008-03-19)

Home chemotherapy is a viable alternative to hospital treatment
Home chemotherapy is a safe and acceptable alternative to hospital treatment for patients with colorectal cancer that may improve compliance with treatment, according to a study in this week's BMJ. Of 87 patients receiving chemotherapy for colorectal cancer, 42 were treated at an outpatient clinic... view more (2001-04-03)

New Diagnostic Faecal Test Could Identify Colorectal Cancer (p 1917)
Authors of a research letter in this week's issue of THE LANCET describe a new technique where the detection of a specific protein in faeces could be a marker for colorectal cancer. Colorectal cancer is a common disease (causing around 500,000 deaths each year worldwide), and screening methods that... view more (2002-05-29)

Mesalamine linked to cancer protection for high risk inflammatory bowel disease patients
Researchers found that mesalamine use among patients with inflammatory bowel disease was associated with a decrease in incidence of colorectal cancer when comparing cases and controls.   view more (2007-10-15)

High intake of dietary fiber not associated with reduced risk of colorectal cancer
In an analysis combining data from 13 studies, high intake of dietary fiber was not associated with reduced risk of colorectal cancer.   view more (2005-12-14)

SURGERY FOR COLORECTAL CANCER IN ELDERLY PATIENTS
Colorectal cancer is the most common malignant disease in elderly people, with over 70% of cases occurring in those aged 65 years or older. Doctors often have to decide whether surgery will be worthwhile in terms of the patient's life expectancy and the quality of life they can expect after... view more (2000-09-14)

Diets high in choline may increase risk for colorectal polyps
Contrary to expectations, diets high in the nutrient choline were associated with an increased risk of some colorectal polyps, which can-but do not always-lead to colorectal cancer.   view more (2007-08-08)

A gene for metastasis
Colorectal cancer is one of the most prevalent cancers in the Western world. The tumor starts off as a polyp but then turns into an invasive and violent cancer, which often spreads to the liver.   view more (2007-08-28)

CT colonography versus colonoscopy for colorectal cancer
Colorectal cancer is the second leading cause of cancer deaths in most developed countries.   view more (2005-10-11)

Study identifies a common genetic risk factor for colorectal and prostate cancer
A study led by researchers at the Keck School of Medicine of the University of Southern California (USC) has found that one of seven genetic risk factors previously identified as increasing the probability of developing prostate cancer also increases the probability of developing colorectal cancer.   view more (2007-07-09)

Smoking can double risk of colorectal polyps
Smokers have a two-fold increased risk of developing colorectal polyps, the suspected underlying cause of most colorectal cancers (CRC), according to a study published in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute.   view more (2008-02-04)

AGA supports new guidelines favoring tests that prevent colorectal cancer
New consensus colorectal cancer guidelines released today state for the first time that the primary goal of colorectal cancer screening is cancer prevention. Previous guidelines have given equal weight to tests for detecting cancer and preventing cancer. By removing polyps from the large bowel,... view more (2008-03-06)

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