Colorectal Epithelial Neoplasias Current Events | Colorectal Epithelial Neoplasias News
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Revised Vienna Classification for diagnosing colorectal epithelial neoplasias
Considerable discrepancies have been reported between diagnoses of colorectal epithelial neoplastic lesions made by Western and Japanese pathologists from endoscopic cold biopsies and resected specimens of the same lesions. view more (2009-06-11)
What is the function of NOD2 in colonic epithelial cells?
NOD2 is a cytosolic pattern recognition receptor similar in structure and function to Toll like receptors (TLRs). It can recognize and respond to a component found in the cell wall of bacteria, muramyl dipeptide (MDP), and has been shown to play an important role in the innate immune response of macrophages to bacterial infections. view more (2008-10-23)
Screening for colorectal cancer should start at age 50
New estimates of the lifetime risk of developing colorectal cancer, published in the Journal of Medical Screening, suggest that screening should start at age 50 or 55 in the general population. For individuals with a family history of colorectal cancer, screening is recommended from age 40-44. Using cancer registry data, researchers in France... view more... (2000-11-20)
Human Cytomegalovirus May Be Involved In Colorectal Cancer (p 1557)
Preliminary findings of a study in this week's issue of THE LANCET suggest that a common human virus may play a part in the cellular processes involved in the development of colorectal cancer. Colorectal cancer is the second most frequent cause of death from cancer in many developed countries; most tumours arise sporadically with no clear cause... view more... (2002-11-13)
Low-fat diet does not reduce risk of colorectal cancer
In an article in the February 8 JAMA, Shirley A. A. Beresford, Ph.D., of the University of Washington, Seattle, and colleagues with the Women's Health Initiative (a study which included nearly 50,000 women) analyzed data from the WHI Dietary Modification Trial to determine the effect of a low-fat eating pattern on risk of colorectal cancer in... view more... (2006-02-08)
New evidence finds no association between coffee consumption and risk of colorectal cancer
There is no association between coffee consumption and risk of colorectal cancer, finds new evidence in Gut, despite previous studies suggesting a protective effect of coffee consumption. This presumption may be premature, report the authors. Paul Terry and colleagues examined data from over 61, 000 Swedish women aged 40-74 years - the largest... view more... (2001-06-14)
What are the risk factors of sporadic colorectal cancer?
Colorectal cancer (CRC) is one of the most common cancers in China. view more (2009-06-12)
Mayo researchers discover mechanism of cell type-specific signaling in tumor development
Mayo Clinic researchers have discovered the mechanisms behind two key checkpoints in cell growth and development - factors that may ultimately allow investigators to benchmark progression of tumor cells or stop them from further development. The findings appear in the current online issue of Developmental Cell. view more (2009-04-08)
DNA test shows promise for identifying patients with colorectal cancer (p 1283)
Testing for DNA changes in stools might provide a new, accurate, and less invasive way to screen patients for colorectal cancer, conclude the authors of a research letter in this week's issue of THE LANCET. Colorectal cancer is one of the most common cancers in the industrialised world, and early detection might help to reduce the risk of death... view more... (2004-04-14)
A new gene for familial cancer was found
A research group at the University of Helsinki, Finland, has found a gene defect that causes hereditary colorectal cancer and defects in dentition. The finding was published online on March 23 in the American Journal of Human Genetics. The groups led by professors Sinikka Pirinen and Irma Thesleff at the Institute of Dentistry and Institute of... view more... (2004-03-26)
Cholesterol-lowering drugs not associated with reduced colorectal cancer risk
Use of cholesterol reducing drugs is not associated with a reduced risk of colorectal cancer, according to a study in the January 4 issue of the Journal of the National Cancer Institute . view more (2006-01-04)
Keyhole Surgery For Colorectal Cancer Offers Same Prognosis As Conventional Surgery (p 1187)
Laparoscopy ('keyhole surgery') for colorectal cancer could be the future treatment of choice after results of a study from Hong Kong in this week's issue of THE LANCET show how it is associated with a similar 5-year survival outcome and more favourable recovery time than conventional surgery. Colorectal cancer is one of the commonest forms of... view more... (2004-04-07)
Obesity strongest risk factor for colorectal cancer among women; greater than smoking
Research presented at the 72nd Annual Scientific Meeting of the American College of Gastroenterology found that obesity, among other important risk factors, was the strongest risk factor for colorectal cancer in women. view more (2007-10-15)
Study confirms colonoscopy associated with reduced colorectal cancer incidence
Patients who undergo a complete negative colonoscopy have a reduced incidence of colorectal cancer, confirms a study published in Clinical Gastroenterology and Hepatology. view more (2008-10-03)
A search for biomarkers for early detection of colorectal cancer
Researchers at the Zhejiang University, Hangzhou have discovered that mimecan and Thioredoxin Domain-Containing Protein 5 (TXNDC5) were differentially expressed in colorectal adenoma. view more (2007-09-25)
Cells united against cancer
Sheets of highly organized epithelial cells line all the cavities and free surfaces of the body, forming barriers that control the movement of liquids and cells in the body organs. view more (2007-08-28)
Scientists discover major genetic cause of colorectal cancer
About one-third of colorectal cancers are inherited, but the genetic cause of most of these cancers is unknown. The genes linked to colorectal cancer account for less than 5 percent of all cases. view more (2008-08-15)
New Diagnostic Faecal Test Could Identify Colorectal Cancer (p 1917)
Authors of a research letter in this week's issue of THE LANCET describe a new technique where the detection of a specific protein in faeces could be a marker for colorectal cancer. Colorectal cancer is a common disease (causing around 500,000 deaths each year worldwide), and screening methods that are more reliable than colonoscopy and... view more... (2002-05-29)
Cancer Research UK supports additional TroVax phase II trial in colorectal cancer
Oxford BioMedica announced today that Cancer Research UK (CRUK) has agreed to conduct and sponsor an open label Phase II trial with Oxford BioMedica's leading cancer immunotherapy product, TroVax®, in colorectal cancer patients who have liver metastases. The decision by CRUK follows extensive review of the successful Phase I/II data of TroVax... view more... (2003-08-28)
Natural protein may halt colorectal cancer's spread
Medical College of Wisconsin Cancer Center researchers in Milwaukee have learned that a protein, CXCL12, that normally controls intestinal cell movement, has the potential to halt colorectal cancer spreading. view more (2009-04-21)
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