Combination Therapy Current Events | Combination Therapy News | 2
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Combination therapy with a monocloncal antibody and a vaccine leads to tumor rejection
Effector T cells (Teff cells) are involved in activating and directing other immune cells, while regulatory T cells (Tregs) act to curb the over-aggressive responses of the T cell population. view more (2006-06-16)
Stem cell infusion and hyperbaric oxygen treatment improve islet function in diabetes
A study to determine if patients with type 2 diabetes can benefit from a combination of autologous (patient self-donated) stem cell infusions (ASC) and hyperbaric (above the normal air pressure of ) oxygen treatment (HBO) before and after ASC has found "significant benefits" in terms of "improvements in glycemic control" along... view more... (2009-03-13)
Diagnostic tests for malaria underused in Zambia
Despite improvements in the ability to diagnose malaria, these diagnostic tests are often underused in Zambia, and patients with negative test results are often prescribed anti-malaria medications. view more (2007-05-23)
2-drug combination appears safe and active in metastatic kidney cancer
Fox Chase Cancer Center investigators report that a two-drug blockade of mTOR signaling appears safe in metastatic kidney cancer in a phase I trial. view more (2009-06-01)
Cognitive behavior therapy appears beneficial for long-term treatment of insomnia
For patients with persistent insomnia, a combination of cognitive behavior therapy (CBT) and the medication zolpidem for 6 weeks was associated with improvement in sleep, although for a longer treatment period CBT alone was more beneficial. view more (2009-05-20)
Certain combination therapy found more effective for treating malaria in African children
Ugandan children who received the combination therapy of artemether-lumefantrine experienced a lower rate of treatment failure compared to other combination therapies, according to a study in the May 23/30 issue of JAMA, a theme issue on malaria. view more (2007-05-23)
Mayo Clinic research shows promise for myeloma patients
Mayo Clinic Cancer Center investigators report that combination therapy with lenalidomide (RevlimidTM) and dexamethasone (combination is called Rev/Dex) looks like a breakthrough treatment for multiple myeloma. view more (2005-09-02)
New Treatment Option For Heroin Addiction (pp 634, 662)
An alternative drug therapy to methadone for the treatment of heroin addiction is proposed by Swedish authors of a study in this week's issue of THE LANCET. Methadone is an established treatment for heroin addiction-however it is usually only given to long-term addicts as there are concerns that it is addictive. Buprenorphine has been suggested... view more... (2003-02-19)
'Multi-target' immune therapy improves outcomes of severe lupus nephritis
A new treatment using a combination of drugs targeting different parts of the immune system improves the recovery rate for patients with severe lupus involving the kidneys, according to a report in the October Journal of the American Society of Nephrology (JASN). view more (2008-07-02)
New study challenges NICE guidelines on adolescent depression
Should adolescents with depression be prescribed antidepressants, and if so, should they be given only with a psychological therapy, as advocated by the National Institute for Health and Clinical Excellence (NICE)" view more (2007-07-20)
Mutations within a conservative region of HCV affects the therapy
At least 200 million individuals are currently infected with hepatitis C virus (HCV) worldwide. Approximately 30%-50% of patients respond to interferon/ribavirin combination therapy. view more (2009-03-31)
Hepatitis C responds best to combo of ribavirin and interferon, study concludes
A combination of the drugs ribavirin and interferon is more effective in treating hepatitis C than using interferon alone, but it also increases the risk of side effects, according to a new systematic review of recent evidence. view more (2005-07-20)
Double binding sites on tumor target may provide future combination therapy
Researchers from the University of Pennsylvania School of Medicine and colleagues at Merck Serono Research in Germany have found that two drugs bind to receptor sites on some tumors in different places at the same time, suggesting the possibility of a new combination therapy for certain types of cancer. view more (2008-04-09)
Small molecule inhibitor shows promise in trastuzumab-resistant metastatic breast cancer
Fox Chase Cancer Center researchers report that a combination of trastuzumab and neratinib (HKI-272) a novel small molecule inhibitor of the HER2 receptor (ErbB2) appears active in women with HER2-positive metastatic breast cancer who have progressed on previous trastuzumab based therapies. view more (2009-05-29)
Early Promise Of Alternative Hormone Treatment For Breast Cancer
A fast-track study in this week's issue of THE LANCET suggests that the drug anastrozole could be an effective option for the treatment of postmenopausal women with hormone-sensitive early breast cancer. Tamoxifen therapy for five years after surgery is the established treatment for postmenopausal women with hormone-sensitive breast cancer.... view more... (2002-06-19)
Chemotherapy with bevacizumab increases risk of blood clots in arteries
Treatment with chemotherapy and bevacizumab, an anticancer drug, is associated with a greater risk of blood clots in patients' arteries compared with treatment with chemotherapy only. view more (2007-08-08)
Antiretroviral Therapy Effective In Reducing Mother-to-child HIV-1 Transmission When Started After Childbirth (p 1171)
Results of a study from Malawi in this week's issue of THE LANCET highlight how antiretroviral therapy targeted at babies soon after childbirth (because their mothers' HIV diagnosis was made around the time of delivery) is still effective in preventing vertical HIV-1 transmission from mothers to their children. Zidovudine and nevirapine have been... view more... (2003-10-08)
Study supports triple combination therapy for HIV
New evidence in this week’s BMJ supports the use of up to three antiviral drugs (triple therapy) to treat people with HIV. view more (2002-03-27)
Combined radiation seed, chemotherapy wafer implants show promise in treating cancerous brain tumors
In the battle against malignant brain tumors, dual implantation of radioactive seeds and chemotherapy wafers following surgery showed promising results in a study led by specialists at the Neuroscience Institute at the University of Cincinnati (UC) and University Hospital. view more (2008-01-18)
Adding antiviral agents to steroids to treat facial paralysis is not linked to improved recovery
Adding an antiviral agent to corticosteroids for treatment of Bell's palsy (a condition characterized by partial facial paralysis) is not associated with improved recovery of facial movement function. view more (2009-06-16)
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