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Scripps research combination therapy obliterates new vessel growth in tumors and retinopathy
While new blood vessel growth from preexisting capillaries ("angiogenesis") is fundamental to survival, the abnormal formation of new blood vessels ("neovascularization") contributes to the pathogenesis of tumor growth and metastasis as well as the vast majority of diseases that lead to catastrophic loss of vision. view more (2007-01-11)
New research provides hope for childhood cancer sufferers
Dr Richard Lock, Head of the Leukaemia Biology Program at the Children's Cancer Institute Australia for Medical Research, Sydney, along with collaborators from the Childrens Hospital Los Angeles and University of Southern California, USA, recently published their findings in the prestigious scientific journal Blood. view more (2007-07-23)
Estrogen-progestin menopausal hormone therapy and risk of lobular and tubular breast cancer
Estrogen-progestin menopausal hormone therapy is associated with a more than two-fold higher relative risk of developing lobular cancer or tubular cancer than of developing ductal cancer. view more (2006-02-17)
Henry Ford Hospital expands research on gene and radiation therapy for prostate cancer
Henry Ford Hospital is embarking on an expanded major clinical trial involving the use of gene therapy in combination with radiation therapy, to determine if the combined treatment is more effective than radiation therapy alone for patients with intermediate risk prostate cancer. view more (2008-02-07)
Old Stain in a New Combination
New combinations of agents based on the oldest synthetic malaria drug, the methylene blue stain, can curb the spread of malaria parasites and make a significant contribution to the long-term eradication called for by the international "Roll Back Malaria Initiative." view more (2009-05-21)
Monthly interpersonal psychotherapy prevents relapse of depression in many women
Most women with recurrent depression may be able to prevent subsequent depressive episodes with monthly maintenance interpersonal psychotherapy (IPT). view more (2007-05-01)
Ugandan Study Highlights Best Drug Combinations For Treating Malaria In Africa (pp 1922, 1950)
ISSUE: 27 November-3 December 2004 EMBARGO: 0001 H (London time) Friday 26 November 2004. In North America the embargo lifts at 6.30pm ET Thursday 25 November 2004. view more (2004-11-24)
Combination therapy shows promising results in patients with advanced lung cancer
An early phase study pairing an experimental targeted therapy with a common anti-inflammatory produced promising results in patients with advanced lung cancer, researchers at UCLA's Jonsson Cancer Center reported. view more (2006-06-01)
Further Evidence That Hrt Does Not Protect Against Cardiovascular Disease (p 2001)
Results of a UK randomised trial published in this week's issue of THE LANCET provides further evidence that hormone replacement therapy (HRT) does not offer women protection against cardiovascular disease. Previous observational studies have suggested that HRT could reduce the risk of coronary heart disease (CHD), but results of randomised trials... view more... (2002-12-18)
Dual renin system blocking drug combo provides additional blood pressure-lowering effects
A combination of two medicines that act against the effects of the enzyme renin are more effective in lowering blood pressure than either of the medicines alone, according to a study presented today at the American College of Cardiology's 56th Annual Scientific Session. view more (2007-03-27)
New drug substantially extends survival in pancreatic cancer
A new form of chemotherapy that destroys new blood vessels that grow around tumors has produced excellent results in a phase II trial of patients with inoperable pancreatic cancer, researchers report at the 33rd Congress of the European Society for Medical Oncology (ESMO) in Stockholm. view more (2008-09-17)
Statins prove life-saving in patients with acute coronary syndromes
Patients who begin aggressive statin therapy while in the hospital for acute coronary syndromes (ACS) have a significantly greater chance of long-term survival. view more (2006-05-12)
Estrogen plus testosterone therapy may increase risk of breast cancer in postmenopausal women
Women who take a combination of estrogen and testosterone to treat the symptoms of menopause may have an increased risk of breast cancer. view more (2006-07-25)
Whites take supplemental breast cancer therapy more often than blacks
A new study finds that white women more frequently take more of the life-prolonging supplemental therapies used to treat breast cancer than African-American women. view more (2007-10-08)
Combination therapy reduces tumor resistance to radiation
Radiation is used to treat a variety of tumors and the response of tumors to radiation is dependent on endothelial cell death, which in turn limits oxygen delivery to the tumor, causing hypoxia and tumor cell death. view more (2007-06-08)
Combination Drug Therapy Offers Hope For Malaria Treatment (pp 3, 9, 18)
Two articles and a Commentary in this week's issue highlight how combination therapy offers the best hope for tackling drug resistance for the millions of people worldwide affected by malaria. Drug resistance is the main barrier to effective malaria treatment. Artemisinin (extract of sweet wormwood , commonly used in Chinese herbal medicine) and... view more... (2003-12-30)
Brain tumors: New therapy surprisingly successful
The combination of two drugs produces a critical improvement in the treatment of certain brain tumours. This has been demonstrated by researchers at Bonn University working in co-operation with German and Swiss colleagues in a current study. view more (2009-03-06)
Self-monitoring of blood glucose
Diabetes patients should always control their own blood sugar values if this leads to improvements in their treatment. view more (2009-09-29)
Hormone therapy boosts sexual interest but not memory, study finds
Hormone therapy in early post-menopause increases sexual interest, but does not improve memory, according to a study in the Sept. 25 issue of the journal Neurology. view more (2007-09-25)
Anti-tumor effects are enhanced by inhibiting 2 pathways rather than 1
Two independent research groups have found that simultaneous inhibition of two signaling pathways resulted in substantially enhanced antitumor effects in mouse models of prostate and breast cancer. In an accompany commentary, Steven Grant, at Virginia Commonwealth University Health Science Center, Richmond, discusses the clinical importance of... view more... (2008-08-22)
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