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ALTERNATIVE PHARMACOLOGICAL STRATEGY FOR TREATMENT OF ACUTE HEART ATTACK (pp 1898, 1905)
Results of the GUSTO V randomised trial - detailed in a fast-track study in this week's issue of THE LANCET - suggest a role for a combination drug strategy for the treatment of acute heart attack. Despite having been the standard of care for acute myocardial infarction (heart attack) since the 1980s, reperfusion (re-establishing blood flow to the... view more... (2001-06-13)
ZOLINZA (vorinostat) in combination with bortezomib demonstrated clinical activity
Results from two investigational Phase I trials of ZOLINZA® (vorinostat) in combination with bortezomib provide preliminary anti-tumor activity in patients with relapsed and/or refractory multiple myeloma. view more (2007-12-10)
Action needed to avoid HIV drug resistance in Africa
We should stop and think about the risks of resistance, and ways of minimising them, before increasing access to antiretroviral therapy in Africa, argue researchers in this week's BMJ. view more (2004-01-29)
Promising Drug Combination May Help Those with Ocular Melanoma that has Spread
A combination of two drugs shows promise in treating a rare and therapy-resistant type of melanoma that originates in the eye and spreads to other organs, according to a new study led by Duke University Comprehensive Cancer Center researchers. view more (2007-09-05)
Researchers Discover New Method to Treat Cancer
Research at Oxford University's Institute of Molecular Medicine has identified a novel therapeutic regimen for the treatment of cancer that provides significant advantages over the existing methods of cancer treatment. There are already a number of regimens available for treatment of cancer, including chemotherapy, which is commonly used to treat... view more... (2003-03-20)
3-drug combination 'extremely promising' as first-line therapy for multiple myeloma
A new combination of bortezomib (Velcade) and two other drugs is showing a very high response rate in patients newly diagnosed with multiple myeloma, a team headed by Dana-Farber Cancer Institute investigators reported at the annual meeting of the American Society of Hematology. view more (2007-12-12)
Complete response with oblimersen combination improves survival of CLL patients
Relapsed chronic lymphocytic leukemia (CLL) patients who had a complete response to combination therapy that included the drug oblimersen survived significantly longer than patients treated with chemotherapy alone, a team led by researchers at The University of Texas M. D. Anderson Cancer Center reports at the 49th Annual Meeting of the American... view more... (2007-12-10)
Study compares treatments for chronic plaque psoriasis
UV-A therapy was found to be more effective than narrowband UV-B therapy in treating patients with chronic plaque psoriasis. view more (2006-07-18)
Ineffective monotherapies common in high-burden malarious countries
ACTwatch, a research project led by PSI, in collaboration with the London School of Hygiene and Tropical Medicine, released evidence today that indicates that artemisinin combination therapy, the most effective medicines for treating malaria, continue to have a significantly low presence on the market among populations considered to be most at... view more... (2009-11-02)
Long-term estrogen therapy linked to breast cancer risk
Long-term estrogen therapy may be related to a higher risk of breast cancer among postmenopausal women who have had a hysterectomy, according to an article in the May 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. view more (2006-05-09)
Higher risks for women with diabetes using HRT
Women with diabetes who use hormone replacement therapy are at an increased risk of death from all causes and heart disease, finds a study in this week’s BMJ. view more (2003-02-19)
Combination of aspirin and an anti-clotting drug reduces risk of dialysis access failure
For the first time, a combination of aspirin and the anti-platelet drug dipyridamole has been shown to significantly reduce blockages and extend the useful life of new artery-vein access grafts used for hemodialysis, according to a study by the Dialysis Access Consortium (DAC). view more (2009-05-21)
Has HIV Become More Virulent?
Damage to patients' immune systems is happening sooner now than it did at the beginning of the HIV epidemic, suggesting the virus has become more virulent. view more (2009-04-08)
Post-stent maintenance therapies questioned
Patients admitted to the hospital with an acute coronary syndrome (ACS) are often treated with a catheter-based procedure known as percutaneous coronary intervention, or PCI. But doctors are unclear about the optimal antithrombotic therapy to prescribe after procedure to prevent clotting. view more (2006-03-15)
Study identifies biomarker that safely monitors tumor response to new brain cancer treatment
A specific biomarker, a protein released by dying tumor cells, has been identified as an effective tool in an animal model to gauge the response to a novel gene therapy treatment for glioblastoma mulitforme. view more (2009-07-01)
Multiple myeloma clinical trial closes early
Mayo Clinic Cancer Center announced today that a multiple myeloma clinical trial has shown a significant improvement in survival with lenalidomide plus low-dose dexamethasone therapy compared to lenalidomide plus high-dose dexamethasone. view more (2007-04-05)
Postmenopausal hormone therapy appears to increase risk of blood clots in veins
Estrogen therapy may increase the risk of venous thrombosis, the formation of blood clots in the veins, among postmenopausal women who have had their uterus removed. view more (2006-04-11)
Brain imaging links chronic insomnia to reversible cognitive deficits without changes in behavior
A neuroimaging study in the Sept. 1 issue of the journal Sleep is the first to find that cognitive processes related to verbal fluency are compromised in people with insomnia despite the absence of a behavioral deficit. view more (2008-09-02)
Switching medications, adding psychotherapy may help teens with ineffective depression medication
For adolescents with depression not responding to an initial treatment with a selective serotonin reuptake inhibitor (SSRI; a class of antidepressant drugs), switching medications and adding cognitive behavioral therapy resulted in an improvement in symptoms, compared to just changing medications. view more (2008-02-27)
LA BioMed study finds hormone therapy increases frequency of abnormal mammograms, breast biopsies
Combined hormone therapy appears to increase the risk that women will have abnormal mammograms and breast biopsies, and it may decrease the effectiveness of both methods for detecting breast cancer. view more (2008-02-26)
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