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Long-term antibiotics reduce COPD exacerbations, raise questions
Long-term use of a macrolide antibiotic may reduce the frequency of exacerbations in patients with moderate to severe chronic obstructive pulmonary disease (COPD) by as much as 35 percent, according to a London-based study. view more (2008-11-21)
New therapy reduces mortality in patients with severe COPD
Patients with severe COPD may benefit more from therapy that combines salmeterol and fluticasone [SFC] than treatment with tiotropium, according to results from a long-term, multi-center study, "Investigating New Standards for Prophylaxis in Reducing Exacerbations" (INSPIRE) that directly compared the two therapies. view more (2007-12-28)
Clinical trials nebulized formoterol fumarate: Long-term and cardiovascular safety COPD
Data from two Phase III clinical trials were presented today in Chicago at CHEST 2007, the annual scientific assembly of the American College of Chest Physicians (ACCP), supporting the use of Perforomist (formoterol fumarate) Inhalation Solution as a safe and effective maintenance treatment for COPD patients. view more (2007-10-25)
High-dose inhaled corticosteroid use for COPD could cut risk of lung cancer
Among a group of mostly older male veterans suffering from chronic obstructive pulmonary disease (COPD), an illness that offers a greater susceptibility to lung cancer, researchers found that regular use of high dose inhaled corticosteroids (ICS) lowered the risk of developing lung cancer. view more (2007-04-02)
Top notch decisions in the developing airways bring insights into lung disease
In the normal lung, the airways are lined by a balanced mixture of ciliated, secretory and neuroendocrine cells which perform functions as diverse as air humidification, detoxification, and clearance of environmental particles. view more (2009-06-09)
Changes in gene may stunt lung development in children
Mutations in a gene may cause poor lung development in children, making them more vulnerable to diseases such as chronic obstructive pulmonary disease (COPD) later in life, say researchers at the University of Pittsburgh Graduate School of Public Health and the German Research Center for Environmental Health. view more (2009-03-27)
LSUHSC shows for first time infant inhalation of ultrafine air pollution linked to adult lung disease
Stephania Cormier, Ph.D., Associate Professor of Pharmacology at LSU Health Sciences Center New Orleans, has shown for the first time that early exposure to environmentally persistent free radicals (present in airborne ultrafine particulate matter) affects long-term lung function. view more (2009-07-23)
Combination therapy reduces exacerbations in severe COPD
For patients with severe chronic obstructive pulmonary disease (COPD), combining a long-acting bronchodilator with an inhaled corticosteroid reduced the number of exacerbations by 35 percent. view more (2007-01-15)
Personalized therapy for asthma and COPD could soon be here
Researchers at Washington University School of Medicine in St. Louis have defined a new type of immune response that is activated in patients with severe asthma and COPD (chronic obstructive pulmonary disease). Their discovery could dramatically improve diagnosis and treatment of patients with chronic inflammatory lung disease. view more (2008-05-19)
Yale study shows why cigarette smoke makes flu, other viral infections worse
A new study by researchers at Yale School of Medicine could explain why the cold and flu virus symptoms that are often mild and transient in non-smokers can seriously sicken smokers. Published in the Journal of Clinical Investigation, the study also identified the mechanism by which viruses and cigarette smoke interact to increase lung... view more... (2008-07-25)
Henry Ford Hospital to study effectiveness of a new procedure that may help emphysema suffers
Researchers at Henry Ford Hospital today announced the start of the EASE (Exhale Airway Stents for Emphysema) Trial, an international, multi-center clinical trial to explore an investigational treatment that may offer a significant new option for those suffering with advanced emphysema. view more (2008-03-13)
Cigarettes leave deadly path by purging protective genes
A University of Rochester scientist discovered that the toxins in cigarette smoke wipe out a gene that plays a vital role in protecting the body from the effects of premature aging. view more (2008-01-24)
UCSF Fresno leading-edge study lends hope to emphysema patients
Patients in the Valley with emphysema might soon be breathing a little easier thanks to a new airway bypass study called the Exhale Airways Stents for Emphysema (EASE) trial. view more (2008-10-22)
Researchers to test if cannabis ingredient can help COPD patients
Researchers from Imperial College London are looking for volunteers to test whether cannabinoids, the active ingredient of cannabis, can be used to alleviate the sensation of breathlessness caused by illnesses such as chronic obstructive pulmonary disease (COPD). view more (2005-09-06)
Lung cancer screening encouraged for smokers with a strong family history of the disease
To detect invasive lung cancer in its early stages, researchers urge current and former smokers who have a strong family history of the disease to take a lung function test and undergo screening with spiral computed tomography. view more (2006-01-03)
Blood test could avoid inappropriate use of antibiotics for respiratory infections (pp 600)
A rapid blood test to help distinguish between bacterial and other (predominantly viral) infections could substantially reduce the inappropriate use of antibiotics for common infections, conclude authors of a study in this week's issue of THE LANCET. Lower respiratory tract infections are often treated with antibiotics-even though there is often... view more... (2004-02-18)
Infection Blocks Lung's Protective Response Against Tobacco Smoke
An infection that often goes undetected can block the lung's natural protective response against tobacco smoke, according to researchers at National Jewish Health. view more (2008-08-20)
Lifestyle program for patients with COPD is health and cost effective
Patients with moderate COPD were randomized to receive "usual care" or to undergo an interdisciplinary, community-based program (INTERCOM) that offered an intensive lifestyle moderation phase of four months, during which patients were instructed in detail to perform two 15-minute intervals of pleasurable walking or cycling, and offered... view more... (2009-05-20)
Study reveals trends in US death rate, leading causes of death over 30 years
The death rate from all causes of death combined decreased by 32 percent between 1970 and 2002, with the largest decreases for heart disease and stroke, but with an increase in death rates for diabetes and COPD. view more (2005-09-14)
Vitamin D may halt lung function decline in asthma and COPD
Vitamin D may slow the progressive decline in the ability to breathe that can occur in people with asthma as a result of human airway smooth muscle (HASM) proliferation, according to researchers at the University of Pennsylvania. view more (2009-05-21)
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