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Researchers aim to cut future need for liver transplants
University of Edinburgh scientists have identified primitive liver cells —possibly dormant from the earliest developmental stage of a human being — which have the potential to mature into different cells types and help repair a failing liver.   view more (2006-07-07)

Arterial, venous or total mesenteric ischemia/reperfusion causes different types of injury?
It is known that I/R induces an inflammatory response deleterious to the organ involved but also to the system as a whole.   view more (2009-08-27)

Cardiac arrest casualties form a valuable source of donor kidneys
A pilot study of a system for harvesting kidneys from non-heart-beating donors where attempts of resuscitation after a witnessed out-of-hospital cardiac arrest have failed (uncontrolled NHBDs) resulted in 21 successful kidney transplants - a 10% increase in the transplantation rate - over 17 months.   view more (2009-08-28)

UPMC performs first beating heart transplant procedure in the US
Protected by its own nutrients and blood supply, a beating heart supported by an investigational organ preservation device was successfully transplanted into a 47-year-old man with congestive heart failure and pulmonary hypertension on Sunday, April 8.   view more (2007-05-18)

Mechanical engineering helps research into the liver
Artificial glass livers being developed at the University of Leeds could help those suffering from liver failure, and improve understanding of how the organ works, researchers believe. Dr Peter Walker of mechanical engineering is leading Leeds' contribution to a three-year £320,000 project that aims to replicate the geometry of the liver,... view more... (2004-01-26)

New coil to make magnetic resonance (MR) imaging easier
Oxford University researchers have devised a novel coil design for magnetic resonance (MR) application, devised specifically for deep organ MR where sensitive imaging and spectroscopy have been previously difficult. Deep organ magnetic resonance requires maximised sensitivity and magnetic field homogeneity over a relatively large field of view... view more... (2003-01-24)

Harvard and U. Pittsburgh researchers explain carbon monoxide's anti-inflammatory effects
In a study appearing in the April 2007 issue of The FASEB Journal, scientists from Harvard University and the University of Pittsburgh have shown for the first time that the anti-inflammatory effects of carbon monoxide originate within cells' own molecular engines, mitochondria.   view more (2007-03-30)

Heart transplants benefit only the sickest patients
Heart transplantation improves survival only in patients with the worst heart failure and therefore at the highest risk of death while on the waiting list, according to a study in this week?s BMJ. This questions the current view in the medical community that transplantation improves the chances of survival for all patients who reach an advanced... view more... (2000-09-01)

'Killer' cells used to combat rare cancer
Scientists from the University of Edinburgh are using immune cells harvested from blood donors to help fight an unusual cancer which can affect transplant patients. And their findings, published recently in The Lancet show that the therapy has proved effective in a number of cases. The treatment proved successful last year in saving the life of a... view more... (2002-09-10)

Blood marker helps predict prognosis among those with abdominal infection
Monitoring blood levels of a compound known as procalcitonin in patients with peritonitis (a serious intra-abdominal infection) could help identify patients at increased risk of organ failure and death.   view more (2007-02-20)

World-famous cancer specialist links hormones to organ growth
New work from internationally renowned cancer specialist Dr Judah Folkman indicates that organ size can be controlled by hormones. This important new finding may have implications for the treatment of a variety of conditions, including endometriosis, abnormal menstrual bleeding, and prostate conditions.   view more (2000-03-07)

Kidney transplants generally safe for lupus patients
Individuals with a history of lupus who receive a kidney transplant rarely develop the serious inflammatory condition lupus nephritis in their new organ, according to a paper being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, CA.   view more (2009-11-02)

Cancer drug effectively treats transplant rejections
University of Cincinnati (UC) researchers have discovered a new therapy for transplant patients, targeting the antibody-producing plasma cells that can cause organ rejection.   view more (2008-12-29)

Vaccine-producing 'plant-factories'
A research team at the Consejo Superior de Investigaciones Científicas (CSIC) has discovered a new route for the transport of proteins in plant cells, a discovery that will enable the biotechnological design of plant factories. Amongst other applications, these can be used to produce oral vaccines which, upon being ingested, will be able to... view more... (2006-11-08)

A potential therapeutic agent for hepatic fibrosis
Accumulating evidence suggests that connective tissue growth factor (CCN2) plays a central role in fibrotic conditions in many organ systems.   view more (2009-08-26)

Embryonic stem cells might help reduce transplantation rejection
Researchers have shown that immune-defense cells influenced by embryonic stem cell-derived cells can help prevent the rejection of hearts transplanted into mice, all without the use of immunosuppressive drugs.   view more (2008-09-16)

New study seeks deeper understanding of bereaved families' attitudes to organ donation
Researchers at the University of Southampton are looking for people to take part in a major new study into organ donation. The national study will look at the decision-making and experiences of bereaved people who after the death of a family member chose not to donate organs or tissues of the deceased relative for transplant operations.   view more (2005-04-05)

Study recommends new tool to assess blunt abdominal trauma
Contrast-enhanced sonography compared with sonography and CT proves to be a useful tool in the assessment of blunt abdominal trauma, concludes a study conducted by the departments of emergency, internal medicine, and radiology at the University of Bologna in Bologna, Italy.   view more (2006-06-30)

Immune cells ameliorate hypertension-induced cardiac damage in mice
Researchers in Berlin, Germany have found that a specific type of immune cell, the regulatory T lymphocyte (Treg) plays an important role in hypertension-induced cardiac damage.   view more (2009-06-10)

Call for closer examination of 'brain death' as the end of life
The medical diagnosis of brain death is at odds with our traditional view of when death actually occurs.   view more (2007-09-12)
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