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U of M Sets Course For Cure of Fatal Childhood Skin Disease
Physicians at the University of Minnesota and University of Minnesota Children's Hospital, Fairview have set the path to a cure for a young boy's fatal genetic skin disease, recessive dystrophic epidermolysis bullosa (RDEB), by using a cord blood and bone marrow transplant. Nate Liao, a 25-month-old from Clarksburg, N.J., underwent the... view more... (2008-06-04)
Novel stem cell technology leads to better spinal cord repair
Researchers believe they have identified a new way, using an advance in stem-cell technology, to promote recovery after spinal cord injury of rats, according to a study published in today's Journal of Biology. view more (2006-04-28)
Pregnancy hormone increases nerve cells' insulation, restores damage
A hormone produced during pregnancy spontaneously increases myelin, which enhances signaling within the nervous system, and helps repair damage in the brain and spinal cord. view more (2007-02-21)
Drug studied as possible treatment for spinal injuries
Researchers have shown how an experimental drug might restore the function of nerves damaged in spinal cord injuries by preventing short circuits caused when tiny "potassium channels" in the fibers are exposed. view more (2009-11-20)
A protein fragment called 12.5 kda cystatin may generate first simple test for multiple sclerosis
Johns Hopkins scientists report the discovery of a protein found only in cerebrospinal fluid that they say might be useful in identifying a subgroup of patients with multiple sclerosis (MS) or identifying those at risk for the debilitating autoimmune disorder. view more (2006-03-03)
Growth factor stimulates rapid extension of key motor neurons in brain
A growth factor known to be important for the survival of many types of cells stimulates rapid extension of corticospinal motor neurons - critical brain cells that connect the cerebral cortex with the spinal cord and that die in motor neuron diseases like amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease). view more (2006-11-06)
Trimming the fat boosts blood recovery after marrow transplant
Seeking ways to improve blood recovery after chemotherapy or bone marrow transplant, researchers at Children's Hospital Boston have discovered that fat cells, which accumulate in bone marrow as people age, inhibit the marrow's ability to produce new blood cells. view more (2009-06-11)
Rutgers University Scientist's Research Reveals Critical Knowledge About the Nervous System
Uncover the neural communication links involved in myelination, the process of protecting a nerve's axon, and it may become possible to reverse the breakdown of the nervous system's electrical transmissions in such disorders as multiple sclerosis, spinal cord injuries, diabetes and cancers of the nervous system. view more (2007-11-07)
Spinal cord bridge bypasses injury to restore mobility
The body's spinal cord is like a super highway of nerves. When an injury occurs, the body's policing defenses put up a roadblock in the form of a scar to prevent further injury, but it stops all neural traffic from moving forward. view more (2006-08-21)
Possible biological explanation for C-Section-linked allergies and asthma found
Scientists believe they may have identified a biological explanation for the link between cesarean-section delivery and risk of allergy and asthma in childhood. view more (2008-05-21)
Powerful technique for multiplying adult stem cells may aid therapies
Adult stem cells may be free of the ethical concerns that hamper embryonic stem cell research, but they still pose formidable scientific challenges. Chief among these is the doggedness with which adult stem cells differentiate into mature tissue the moment they're isolated from the body. view more (2006-01-23)
Columbia University researchers discover on-off switch for chronic pain
Chronic pain affects approximately 48 million people in the U.S. and current medications are either largely ineffective or have serious side effects. view more (2006-07-20)
Spinal fluid proteins signal Lou Gehrig's disease
High levels of certain proteins in the spinal fluid could signal the onset of Lou Gehrig's disease, according to researchers. The discovery of these biomarkers may lead to diagnostic kits for early diagnosis, accurately measuring the progression of the disease and monitoring the effects of treatment. view more (2009-01-29)
Morning people and night owls show different brain function: University of Alberta study
Are you a "morning person" or a "night owl?" Scientists at the University of Alberta have found that there are significant differences in the way our brains function depending on whether we're early risers or night owls. view more (2009-06-24)
Study Suggests Link Between Down's Syndrome And Neural-tube Defects (pp 1316, 1331)
Authors of a study in this week's issue of THE LANCET highlight how infants born within families who have a high risk of neural-tube defects (NTD) could also be at an increased risk of Down's syndrome-and vice versa, suggesting an association between Down's syndrome and NTD. NTD are birth defects of the brain or spinal cord caused by abnormal... view more... (2003-04-16)
Low vitamin D during pregnancy linked to preeclampsia
Vitamin D deficiency early in pregnancy is associated with a five-fold increased risk of preeclampsia. view more (2007-09-10)
Breakthrough gives spinal injury sufferers a standing start
For the first time, engineers have enabled paralysed people to stand up and balance for significant periods without holding an external support. This is an important breakthrough in helping individuals with spinal cord injuries to start standing again for useful lengths of time - up to seven minutes have been achieved in experiments. The... view more... (2003-01-16)
Advance helps explain stem cell behavior
Biochemists at Oregon State University have developed a new method to identify the "DNA-binding transcription factors" that help steer stem cells into forming the wide variety of cells that ultimately make up all the organs and parts of a living vertebrate animal. view more (2006-11-21)
Human stem cells delay start of Lou Gehrig's disease in rats
Researchers at Johns Hopkins have shown that transplanting human stem cells into spinal cords of rats bred to duplicate Lou Gehrig's disease delays the start of nerve cell damage typical of the disease and slightly prolongs life. view more (2006-10-16)
Promising therapy for ALS delivers antisense drug directly to nervous system
Researchers from the University of California, San Diego (UCSD) School of Medicine, the Center for Neurologic Study and Isis Pharmaceutical Corporation have designed and tested a molecular therapy in animals that they hope will be a major development in the fight to treat amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease. view more (2006-07-27)
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