Cox-2 Enzyme Current Events | Cox-2 Enzyme News
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New understanding of COX-1 and COX-2 enzymes could lead to revised classification of pain meds, Queen's study shows COX-1 and COX-2 enzymes may be blocked by pain medications such as Advil and Vioxx in a more complex manner than was previously understood, a Queen's University study has found. view more (2006-05-30)
New study may explain Vioxx side effects Vioxx and related pain medications were taken off the market in 2004 because they caused dangerous heart problems in some people. view more (2007-08-28)
Blocking previously unrecognized links between inflammatory systems could make COX-2 inhibitors safe A recently identified path of inflammation once thought to be wholly independent of other inflammatory systems has now been linked to another major pathway. view more (2005-12-23)
Regular use of selective COX-2 inhibitors decreases risk of breast cancer Regular use of selective COX-2 inhibitors significantly reduces the risk of breast cancer. view more (2006-01-30)
'Vioxx like' drugs may still be best option for arthritis, write scientists Scientists believe that despite the current concerns around anti-inflammatory drugs like Vioxx, they may still be the best option for treating some forms of arthritis. view more (2006-01-19)
Is short-term Celecoxib intervention a effective method for preventing gastric carcinogenesis? Since the isolation and culture of Helicobacter pylori (H. pylori) in 1983, this bacterium has become accepted as an important human pathogen for the development of gastritis, peptic ulcer, and gastric cancer. view more (2009-10-29)
Study demonstrates the anti-inflammatory properties of pine bark extract A recent study published in International Immunopharmacology, reveals why Pycnogenol (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree, is effective for reducing inflammation and soothing pain associated with various health problems. view more (2009-07-15)
More fish oil, less vegetable oil, better for your health Scientists have provided new evidence that using more fish oil than vegetable oil in the diet decreases the formation of chemicals called prostanoids, which, when produced in excess, increase inflammation in various tissues and organs. view more (2007-07-27)
Blood cells linked to heart attacks, other inflammatory diseases Two human blood cells that help fight blood loss, infection, and inflammation are responsible as well for starting a series of molecular events that results in overproduction of Cox-2, an enzyme involved in heart attack, stroke, atherosclerosis, and other inflammatory diseases. view more (2006-10-09)
Pick your COX partners Researchers at the University of Pennsylvania School of Medicine and Queen's University, Ontario, Canada report in the online edition of Nature Medicine this week that the COX enzymes — well-known for their contrasting role in cardiovascular biology — interact physically to form a previously unrecognized biochemical partnership and... view more... (2006-06-08)
Study first: Over-expression of Cox-2 can predict prostate cancer outcome Researchers say an over-expression of COX-2 in men with prostate cancer is associated with an increase in PSA after radiation treatment and the spread of the cancer outside of the prostate. view more (2006-11-09)
Therapeutic prospects beyond Vioxx Researchers at the University of Pennsylvania School of Medicine have clarified the mechanism by which drugs like Celebrex and Vioxx cause heart problems, in multiple animal models. view more (2006-04-14)
Licorice compound offers new cancer prevention strategy A chemical component of licorice may offer a new approach to preventing colorectal cancer without the adverse side effects of other preventive therapies, Vanderbilt University Medical Center researchers report. view more (2009-03-24)
Safety claims of new arthritis drugs may be misleading Popular arthritis drugs, known as selective COX 2 inhibitors, may not be superior to traditional non-steroidal anti-inflammatory drugs, conclude researchers in this week’s BMJ. view more (2002-05-28)
COX-2 inhibitors delay pancreatic cancer precursors in mice Nimesulide, a cyclooxygenase-2 (COX-2) inhibitor, delays the progression of precancerous pancreatic lesions in mice, according to researchers at David Geffen School of Medicine at UCLA. view more (2007-08-02)
Penn study suggests a new type of pain reliever that may benefit the heart Building on previous work, researchers at the University of Pennsylvania School of Medicine have found that deleting an inflammation enzyme in a mouse model of heart disease slowed the development of atherosclerosis. view more (2006-09-13)
Ireland Cancer Center researcher lays out benefits of aspirin to prevent colon cancer A colon cancer researcher at the Ireland Cancer Center of University Hospitals Case Medical Center (UHCMC) has laid out the roadmap for how medical science should employ aspirin and new aspirin-like drugs for use in preventing colon cancer in certain high-risk individuals. view more (2007-05-24)
Researchers resolve how COX inhibitors cause heart hazards, and offer alternative treatment strategy Inhibitors of cyclooxygenase-2 (COX-2) were developed to relieve inflammatory pain as effectively as nonsteroidal anti-inflammatory drugs (NSAIDS), but without one of their major side effects, gastrointestinal bleeding. view more (2006-04-14)
COX-2 expression is marker for cancer development in some benign breast biopsies It's a good news, bad news situation. Some women who have a breast biopsy are told that while they don't have cancer, they do have atypical hyperplasia -- cells that aren't quite normal and might become cancerous someday. This happens to one-fourth of women undergoing breast biopsies but no one knows which individuals are at risk. view more (2008-03-12)
Anti-inflammatory effects of omega 3 fatty acid in fish oil linked to lowering of prostaglandin Omega 3 fatty acids in dietary fish oil are reported to have anti-inflammatory and anti-thrombogenic and anti-arrhythmic effects in humans, but the biochemical basis for these beneficial health effects is not well understood. view more (2006-04-04)
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