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Cox-2 Inhibitors Current Events | Cox-2 Inhibitors News
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Regular use of selective COX-2 inhibitors decreases risk of breast cancer
Regular use of selective COX-2 inhibitors significantly reduces the risk of breast cancer. view more (2006-01-30)
'Vioxx like' drugs may still be best option for arthritis, write scientists
Scientists believe that despite the current concerns around anti-inflammatory drugs like Vioxx, they may still be the best option for treating some forms of arthritis. view more (2006-01-19)
Safety claims of new arthritis drugs may be misleading
Popular arthritis drugs, known as selective COX 2 inhibitors, may not be superior to traditional non-steroidal anti-inflammatory drugs, conclude researchers in this week’s BMJ. view more (2002-05-28)
New arthritis drugs less likely to cause side effects
A new group of arthritis drugs recommended by NICE for patients at risk of gastrointestinal complications may be safer than traditional drugs, research in this week's BMJ suggests. Claims that the drugs, known as selective COX2 inhibitors, caused fewer gastrointestinal problems than traditional arthritis drugs led to an increase in their use, but... view more... (2002-09-18)
Researchers resolve how COX inhibitors cause heart hazards, and offer alternative treatment strategy
Inhibitors of cyclooxygenase-2 (COX-2) were developed to relieve inflammatory pain as effectively as nonsteroidal anti-inflammatory drugs (NSAIDS), but without one of their major side effects, gastrointestinal bleeding. view more (2006-04-14)
Is short-term Celecoxib intervention a effective method for preventing gastric carcinogenesis?
Since the isolation and culture of Helicobacter pylori (H. pylori) in 1983, this bacterium has become accepted as an important human pathogen for the development of gastritis, peptic ulcer, and gastric cancer. view more (2009-10-29)
New study re-evaluates cardiovascular risks of anti-inflammatory drugs
High doses of some traditional non-steroidal anti-inflammatory drugs (NSAIDS) are associated with similar cardiovascular risks as the new generation of anti-inflammatory drugs known as COX 2 inhibitors (like Vioxx ®), finds a study in this week's BMJ. view more (2006-06-02)
New understanding of COX-1 and COX-2 enzymes could lead to revised classification of pain meds, Queen's study shows
COX-1 and COX-2 enzymes may be blocked by pain medications such as Advil and Vioxx in a more complex manner than was previously understood, a Queen's University study has found. view more (2006-05-30)
COX-2 inhibitor could be safest anti-inflammatory drug for older people (p 1751)
A Canadian study involving over 130,000 older people in this week's issue of THE LANCET shows how the anti-inflammatory cyclo-oxygenase-2 (COX-2) inhibitor celecoxib may have a lower risk of congestive heart failure compared with other non-steroidal anti-inflammatory drugs. Non-selective, non-steroidal anti-inflammatory drugs (NSAIDs) are... view more... (2004-05-26)
COX-2 inhibitors delay pancreatic cancer precursors in mice
Nimesulide, a cyclooxygenase-2 (COX-2) inhibitor, delays the progression of precancerous pancreatic lesions in mice, according to researchers at David Geffen School of Medicine at UCLA. view more (2007-08-02)
Most NSAIDs raise risk of death after heart attack
Taking either COX-2 inhibitors or other non-steroidal anti-inflammatory drugs (NSAIDs) after a heart attack, especially in high doses, increases the risk of death, researchers reported at the American Heart Association's Scientific Sessions 2005. view more (2005-11-14)
USC researchers develop new drug to target tumor cells and blood vessels
Researchers at the University of Southern California have identified a new drug compound that appears to target tumor cells and surrounding blood vessels without the negative side effects typically associated with Cox-2 inhibitors. view more (2009-04-20)
New study may explain Vioxx side effects
Vioxx and related pain medications were taken off the market in 2004 because they caused dangerous heart problems in some people. view more (2007-08-28)
Therapeutic prospects beyond Vioxx
Researchers at the University of Pennsylvania School of Medicine have clarified the mechanism by which drugs like Celebrex and Vioxx cause heart problems, in multiple animal models. view more (2006-04-14)
Pick your COX partners
Researchers at the University of Pennsylvania School of Medicine and Queen's University, Ontario, Canada report in the online edition of Nature Medicine this week that the COX enzymes — well-known for their contrasting role in cardiovascular biology — interact physically to form a previously unrecognized biochemical partnership and... view more... (2006-06-08)
COX-2 Inhibitors Significantly Reduce Risk of Cancer
Results from a new, five-year study show that regular use of popular prescription pain relievers may reduce the risk of breast cancer by up to 71 percent and may offer similar benefit in the prevention of prostate, colon and lung cancers. view more (2006-04-04)
MUHC study reveals Vioxx related heart attacks can occur within the first two weeks of use
A quarter of patients who suffered a heart attack while taking Vioxx did so within the first two weeks of taking the drug, a new study published by MUHC investigators reveals. view more (2006-05-03)
Penn study points to how COX-2 inhibitors can eventually lead to heart disease
University of Pennsylvania School of Medicine researchers have found additional evidence that may help explain how selective inhibitors of COX-2 might predispose individuals to heart disease and stroke. view more (2005-05-25)
Blocking previously unrecognized links between inflammatory systems could make COX-2 inhibitors safe
A recently identified path of inflammation once thought to be wholly independent of other inflammatory systems has now been linked to another major pathway. view more (2005-12-23)
Study first: Over-expression of Cox-2 can predict prostate cancer outcome
Researchers say an over-expression of COX-2 in men with prostate cancer is associated with an increase in PSA after radiation treatment and the spread of the cancer outside of the prostate. view more (2006-11-09)
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