Cox-2 Inhibitors Current Events | Cox-2 Inhibitors News | 10
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Possible New Cure for Psoriasis
Cell biologists of the University of Bonn, in cooperation with the University of Leeds (U.K.) and industry may have discovered a new effective therapy for psoriasis: a specific group of what are known as metalloproteinase inhibitors can normalise the increased tendency of epidermis cells (keratinocytes) to divide, which is the cause of this... view more... (2004-08-16)
Transplants In HIV Patients Should Proceed But Drug Interactions Can Be Concern, Concludes Research At International Congress Of The Transplantation Society
While historically surgeons have been reluctant to transplant patients with the human immunodeficiency virus (HIV), in recent years, some centers have begun to accept patients with well-controlled HIV as candidates for liver or kidney transplantation. Based on results of three studies from the United States and one from France, which collectively... view more... (2002-08-20)
Focus on lung cancer: How to prevent and treat it
Since smoking became popular in America in the 1930s, lung cancer rates have continued to climb. view more (2005-11-02)
The dietary supplement genistein can undermine breast cancer treatment
Women taking aromatase inhibitors to treat breast cancer or prevent its recurrence should think twice before also taking a soy-based dietary supplement, researchers report. view more (2008-09-24)
New cancer drug hope
Scientists helping to develop the next generation of cancer-beating drugs say they have had a major breakthrough with their latest results. view more (2006-10-27)
NEW APPROACH TO LUNG TRANSPLANTATION FROM A DONOR WITH A NON-BEATING HEART (pp 819, 825)
The shortage of lungs for transplantation could be overcome by a new ethical and surgical approach detailed in this week's issue of THE LANCET. Organ transplantation usually occurs when a donor's heart is still beating; however, lungs that are cooled can be preserved for 12-24 hours after the heart has stopped beating. Stig Steen and colleagues... view more... (2001-03-15)
Enzyme may hold key to new treatment of diabetic kidney disease
Northwestern University Feinberg School of Medicine researchers have found that an enzyme called ACE2 may hold the potential to treat diabetic kidney disease, the most common form of kidney disease. view more (2006-11-08)
Is esomeprazole the best choice for reflux esophagitis patients?
In patients with gastroesophageal reflux disease (GERD), esomeprazole, has demonstrated pharmacological and clinical benefits beyond those seen with the other proton pump inhibitors( PPIs ). view more (2009-03-03)
Researchers restore missing protein in rare genetic brain disorder
UCSF researchers have successfully used protease inhibitors to restore to normal levels a key protein involved in early brain development. Reduced levels of that protein have been shown to cause the rare brain disorder lissencephaly, which is characterized by brain malformations, seizures, severe mental retardation and very early death in human... view more... (2009-09-08)
Novel strategy under study for aggressive leukemia
A novel strategy to hopefully beat into oblivion one of the most aggressive forms of acute myelogenous leukemia combines the strengths of some of the newest leukemia agents, researchers say. view more (2007-09-25)
First high-res 3D structures of mammalian HSP90 protein solved
Dr. Dan Gewirth, Hauptman-Woodward senior research scientist, has just solved the structure of the first mammalian GRP94 protein implicated in immune diseases such as sepsis, AIDS and certain cancers. view more (2007-10-15)
Study provides clues to prevent spread of ovarian cancer
A drug that blocks production of an enzyme that enables ovarian cancer to gain a foothold in a new site can slow the spread of the disease and prolong survival in mice, according to a study by researchers from the University of Chicago Medical Center, but only if the drug is given early in the disease process. view more (2008-03-14)
Combination therapy shows promising results in patients with advanced lung cancer
An early phase study pairing an experimental targeted therapy with a common anti-inflammatory produced promising results in patients with advanced lung cancer, researchers at UCLA's Jonsson Cancer Center reported. view more (2006-06-01)
Study suggests brain tumors need treatment with multiple 'targeted' drugs
Researchers at Dana-Farber Cancer Institute have shown that several, rather than just one, cell-growth switches are simultaneously overactive in many brain tumors and other solid tumors, explaining why treatment with just a single "targeted" switch-blocking drug often yields disappointing results. view more (2007-09-14)
Critical link in cell death pathway revealed
The role of a protein called XIAP in the regulation of cell death has been identified by Walter and Eliza Hall Institute researchers and has led them to recommend caution when drugs called IAP inhibitors are used to treat cancer patients with underlying liver conditions. view more (2009-07-23)
Breast cancer drugs may slow growth of lung cancer
A few years ago researchers discovered that, much like breast tumors, some lung tumors also thrive on estrogen. Now a medical student conducting research on a Howard Hughes Medical Institute (HHMI) fellowship and colleagues have managed to stop the growth of human lung cancer cells in mice with a class of breast cancer drugs called aromatase... view more... (2005-12-15)
Effectiveness of certain antidepressants may be influenced by gene variations of individuals
Whether specific types of antidepressants are effective for patients with late-life major depression may depend if they have certain genetic variations. view more (2006-10-04)
Mutation of the COX2 gene can double or treble a woman's risk of ovarian cancer
Researchers in Portugal have discovered that a specific mutation of the COX2 gene seems to play a role in the onset of ovarian cancer, increasing women's susceptibility to developing the disease. view more (2007-09-26)
Invititation to the Media - Soils as carbon sinks-a breathing space in the race against global warming?
Can we use land carbon sinks as a way to buy time for the restructuring of our energy generation? "We estimate soil carbon sinks could mitigate 8% of the EU`s emissions if major changes were made in land use and agricultural management ," says Professor David Powlson of IACR Rothamsted. However; How many of the land-use options are practicable?... view more... (2002-06-26)
NSAIDs: Painkillers, inflammation inhibitors, anti-cancer drugs and new de-methylating agents
Researchers at the National Sun Yat-Sen University and Kaohsiung Medical University, Kaohsiung, Taiwan have revealed a new mechanism by which nonsteroidal anti-inflammatory drugs (NSAIDs) attenuate tumor invasion and metastasis. view more (2008-03-27)
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