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Cox-2 Inhibitors Current Events | Cox-2 Inhibitors News | 3

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Electroacupuncture protects acetylsalicylic acid-induced acute gastritis in rats
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used as anti-inflammatory and analgesic agents. However, they often cause gastrointestinal injury in gastric lesions by inhibiting COX (cyclooxygenase) and detailed mechanism remains unclear. Thus, effective strategies are required to protect the gastrointestinal mucosa.   view more (2009-03-03)

Brain study may lead to improved epilepsy treatments
Using a rodent model of epilepsy, researchers found one of the body's own neurotransmitters released during seizures, glutamate, turns on a signaling pathway in the brain that increases production of a protein that could reduce medication entry into the brain.   view more (2008-04-15)

COX-2 expression is marker for cancer development in some benign breast biopsies
It's a good news, bad news situation. Some women who have a breast biopsy are told that while they don't have cancer, they do have atypical hyperplasia -- cells that aren't quite normal and might become cancerous someday. This happens to one-fourth of women undergoing breast biopsies but no one knows which individuals are at risk.   view more (2008-03-12)

Blood pressure drug shows potential as lung cancer treatment
A hormone that is important in the control of blood pressure also shrinks lung cancer tumors in mice, suggesting a new way to prevent or treat the deadly cancer, according to scientists at Wake Forest University School of Medicine.   view more (2007-03-15)

Ibuprofen puts high risk cardiac patients at risk
Doctors who treat the painful condition of osteoarthritis in patients with increased cardiovascular risk need to be cautious. A team lead by researchers at Mount Sinai School of Medicine, are the first to study outcomes in high cardiovascular risk patients with osteoarthritis.   view more (2007-04-06)

Top anti-arthritis drugs cause skin disease (embargo changed)
Members of the second most important family of drugs used to treat rheumatoid arthritis can cause serious dermatological conditions in a quarter of patients under treatment, reveals a study published today in the journal Arthritis Research and Therapy.   view more (2005-03-31)

New Manager For Europe's Leading Technology Business Angel Network
Oxfordshire Investment Opportunity Network (OION), Europe's leading technology business angel network, today announced the appointment of Jon Cox as its new Manager. Dr Cox takes over from Alastair Cavanagh who led the OION Network to its position as the pre-eminent investment forum for high growth potential technology companies, raising... view more... (2004-08-16)

Inflammation in colon may get doused before fueling cancer development
A tiny molecule found in most plant-based foods douses the flames before damaging lesions can form in the colon, according to a study by Texas AgriLife Research scientist Dr. Nancy Turner.   view more (2009-02-03)

Aromatase inhibitors: A treatment of choice for advanced breast cancer patients
Aromatase inhibitors improve the survival of advanced breast cancer patients compared to standard hormone therapies like tamoxifen.   view more (2006-09-20)

New training technique helps alcoholics in battle with the booze
A new training technique developed in the UK is proving successful in helping excessive drinkers curb their alcohol abuse. Researchers funded by the Economic and Social Research Council have experimentally tested a computer-based training programme which helps abusive drinkers pay less attention to alcohol, feel more in control of their drinking... view more... (2006-07-24)

High-energy clamp simplifies heart surgery for atrial fibrillation
Heart surgeons at Washington University School of Medicine in St. Louis have helped usher in a new era in the surgical treatment of atrial fibrillation.   view more (2006-10-11)

Antioxidants may protect against tick-borne illness
Researchers are investigating the role that antioxidants - alpha-lipoic acid and potentially others like green tea and vitamins C and E, for example - might play in preventing or treating the deadly rickettsia bacteria.   view more (2006-08-10)

Aspirin Does Not Reduce Effectiveness Of ACE Inhibitors
A systematic review in this week's issue of THE LANCET provides clarification for the debate about the use of angiotensin-converting-enzyme (ACE) inhibitors in combination with aspirin for the treatment of cardiovascular disease-combination therapy does not reduce the effect of ACE inhibition. Previous research has suggested that ACE inhibitors... view more... (2002-10-02)

Drugs may not delay onset of dementia; and more
Researchers have examined the evidence in favour of giving people considered to be close to developing dementia the drugs that are most commonly used to treat the condition itself.   view more (2007-11-27)

Combination therapy reduces tumor resistance to radiation
Radiation is used to treat a variety of tumors and the response of tumors to radiation is dependent on endothelial cell death, which in turn limits oxygen delivery to the tumor, causing hypoxia and tumor cell death.   view more (2007-06-08)

Surgeons announce advance in atrial fibrillation surgery
Heart surgeons at Washington University School of Medicine in St. Louis report that by adding a simple 10-20 second step to an operative procedure they achieved a significant improvement in the outcome for the surgical treatment of atrial fibrillation (AF).   view more (2008-04-08)

Researchers find not all drugs are equal in treating teen drivers with ADHD
Researchers at the University of Virginia Health System have found that teenage drivers with attention deficit hyper activity disorder (ADHD) drive better when they took OROS methylphenidate (OROS MPH), a controlled-release stimulant, rather than extended release amphetamine salts (se-AMPH ER).   view more (2006-09-06)

Experiments point to new treatments for PKD
A family of small molecules called CFTR inhibitors show promising effects in slowing the progression of polycystic kidney disease (PKD), the most common genetic disease of the kidneys, according to preliminary research reported in the July 2008 issue of the Journal of the American Society Nephrology.   view more (2008-04-03)

A new approach to study flu drug resistance
Researchers have created a new approach for studying resistance to Neuraminidase Inhibitors (NI) in influenza.   view more (2007-12-07)

ACE inhibitors may reduce death, heart attack and stroke in patients with coronary artery disease
ngiotension-converting enzyme (ACE) inhibitors, medications commonly used to treat hypertension (high blood pressure), may reduce cardiovascular risk and the risk of death in patients with coronary artery disease.   view more (2006-04-11)
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