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Popular Arthritis Drug May Disrupt Heart Rhythm, UB Research Finds
Celebrex, a popular arthritis drug that blocks pain by inhibiting an enzyme known as COX-2, has been shown in laboratory studies to induce arrhythmia, or irregular beating of the heart, via a novel pathway unrelated to its COX-2 inhibition. view more (2008-01-25)
Anti-inflammatory effects of omega 3 fatty acid in fish oil linked to lowering of prostaglandin
Omega 3 fatty acids in dietary fish oil are reported to have anti-inflammatory and anti-thrombogenic and anti-arrhythmic effects in humans, but the biochemical basis for these beneficial health effects is not well understood. view more (2006-04-04)
K-State researcher examining why common anti-inflammatory drugs harm intestines
New versions of drugs like buffered aspirin and Vioxx could produce fewer harmful side effects thanks to research being done at Kansas State University's College of Veterinary Medicine. view more (2007-06-25)
New Weapon for Fighting Antibiotic Drug Resistance
The most important antibiotics in general use today are the b-lactam family of products, but the medical community faces a serious problem with these antibiotics: the increasing development of drug resistance. The resistance is caused by hydrolysis of the b-lactam by a bacterial lactamase enzyme, but fortunately it can often be overcome by the use... view more... (2003-08-11)
Looking for privacy in the clouds
Millions of Internet users have been enjoying the fun -- and free -- services provided by advertiser-supported online social networks like Facebook. But Landon Cox, a Duke University assistant professor of computer science, worries about the possible down side -- privacy problems. view more (2009-10-14)
Benefits Of Anti-Clotting Drug Class For People With Acute Coronary Syndromes - But For Men Only? (p 189)
Results of a meta-analysis in this week's issue of THE LANCET lend further support to the benefits of the anti-clotting drugs glycoprotein IIb/IIIa inhibitors for the treatment of patients with acute coronary syndromes. However, an unexpected finding of the study suggests that men might be more likely to benefit from therapy with this class of... view more... (2002-01-17)
Opiates and cannaboids: the fight against pain
Opiates and cannaboids, apart from being drugs, have curative properties. Thus, opiates (morphine, methadone, etc.) have been used for some time as a pain-reducer and many cannaboids have also analgesic properties. Regarding their curative aspects, it is very important to know the effects produced after a prolonged period of treatment. Carrying... view more... (2003-03-18)
Mayo Clinic study finds heart transplant patients benefit from new approach to immunosuppression
A new immunosuppression regimen for heart transplant patients can improve kidney function and prevent transplant coronary artery disease, according to two new Mayo Clinic studies. view more (2007-04-26)
Mayo Clinic study finds heart transplant patients benefit from new approach to immunosuppression
A new immunosuppression regimen for heart transplant patients can improve kidney function and prevent transplant coronary artery disease, according to two new Mayo Clinic studies. view more (2007-04-27)
Mutation database helps personalized treatment of lung cancer
A groundbreaking free tool to help oncologists choose the best therapies for patients with non-small-cell lung cancer has been launched this week by scientists at the 1st European Lung Cancer Conference jointly organized by the European Society for Medical Oncology (ESMO) and the International Association for the Study of Lung Cancer (IASLC) in... view more... (2008-04-25)
Commonly used ulcer drugs may offer treatment potential in Alzheimer's disease
In a new study, published in the May issue of Elsevier's Experimental Neurology, scientists at the University of British Columbia have discovered that drugs commonly used to treat ulcers have significant neuroprotective properties, which appear to be enhanced when used in combination with ibuprofen, a widely used anti-inflammatory drug. view more (2009-04-22)
UCLA study shows altering fatty acid levels in diet may reduce prostate cancer growth rate
UCLA researchers found that altering the fatty acid ratio found in the typical Western diet to include more omega-3 fatty acids and decrease the amount of omega-6 fatty acids may reduce prostate cancer tumor growth rates and PSA levels. view more (2006-08-01)
Zebrafish to shed light on human mitochondrial diseases
Zebrafish can now be used to study COX deficiencies in humans, a discovery that gives scientists an unprecedented window to view the earliest stages of mitochondrial impairments that lead to potentially fatal metabolic disorders. view more (2007-09-14)
Specific Genotype Could Increase Resistance To HIV Drug Therapy (p 383)
A specific mutation of a gene which influences the expression of a glycoprotein transporter protein involved in the body's resistance to drugs and other toxins is detailed in a research letter in this week's issue of THE LANCET. Results of the study suggest that drug therapies used in treating HIV-1 infection (notably protease inhibitors ) may not... view more... (2001-08-01)
Ace Inhibitors Could Slow Muscle Decline (p 926)
Angiotensin-converting enzyme (ACE) inhibitors, a class of drugs used to lower blood pressure, could also be protective against the decline in muscle strength in elderly women suggest authors of a study in this week's issue of THE LANCET. ACE inhibitors are known to prevent the decline in physical function in patients with congestive heart failure... view more... (2002-03-13)
Nasal polyps from analgesics
If a patient develops respiratory problems after taking analgesics, this indicates that the active substances are poorly tolerated. view more (2008-03-11)
Future therapies for stroke may block cell death
A new therapy to re-activate silenced genes in patients who suffer from neurodegenerative diseases or stroke is being developed by researchers at the University of Illinois at Chicago and Cornell University. view more (2007-06-14)
Gains in the fight against acid aspiration lung injury
Doctors are gaining new leverage in the fight against lung injury caused by acid reflux. The paper by Bonnans et al., "Lipoxin A4 regulates bronchial epithelial cell responses to acid injury," appears in the April issue of The American Journal of Pathology and is accompanied by a commentary. view more (2006-05-03)
Researchers find potential celebrex target in lung cancer
A product produced by lung cancer tumors fuels the cells that suppress immune function in patients and may be a target for Celebrex therapy, giving oncologists another weapon to fight cancer, according to a study by researchers at UCLA's Jonsson Cancer Center. view more (2005-07-15)
First trimester use of ACE inhibitors implicated in birth defects
The Food and Drug Administration is examining study data from Vanderbilt University Medical Center researchers, published this week in the New England Journal of Medicine, to determine if new warnings should be placed on common blood pressure medications indicating an increased risk of birth defects for babies whose mothers take these medications... view more... (2006-06-08)
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