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Duke team finds compounds that prevent nerve damage
Duke University Medical Center scientists have made a significant finding that could lead to better drugs for several degenerative diseases including Huntington's disease and Alzheimer's disease. view more (2008-09-24)
'Shock and kill' research gives new hope for HIV-1 eradication
Latent HIV genes can be 'smoked out' of human cells. The so-called 'shock and kill' technique, described in a preclinical study in BioMed Central's open access journal Retrovirology, might represent a new milestone along the way to the discovery of a cure for HIV/AIDS. view more (2009-06-04)
13 percent of women stop taking breast cancer drug because of side effects, U-M study finds
More than 10 percent of women with breast cancer stopped taking a commonly prescribed drug because of joint and muscle pain, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center. view more (2007-09-06)
Research suggests that immune response protects against brain tumor development
In their quest to determine whether immune system surveillance guards against brain tumor development, researchers at The University of Texas M. D. Anderson Cancer Center have found that allergies and asthma that stimulate inflammation may be protective, but use of antihistamines to control the inflammation could eliminate that protection. view more (2006-04-03)
Potent Peptides Inhibit HIV Entry Into Cells
Based in part on protein structures determined at the National Synchrotron Light Source (NSLS) at the U.S. Department of Energy's Brookhaven National Laboratory, scientists at the University of Utah have developed new peptides that appear to be significantly more effective at blocking HIV's entry into cells than other drugs in their class. view more (2007-10-11)
Drug-eluting stents better than bare-metal stents for heart attack patients
Late-breaking data from the landmark HORIZONS-AMI clinical trial, presented at the 21st annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium, demonstrated that after two years, in heart attack patients, the use of a drug-eluting stent (paclitaxel) was safer and more effective than a bare-metal stent; and that the... view more... (2009-09-28)
Study finds blocking angiogenesis signaling from inside cell may lead to serious health problems
Angiogenesis inhibitors that block a tumor's development of an independent blood supply have been touted as effective cancer fighters that result in fewer side effects than traditional chemotherapy. view more (2007-08-24)
The good and bad side of anti-cancer compounds
Compounds known as "HDAC inhibitors" exhibit cancer-killing activities in cultured cells. While they are currently being tested as anti-cancer agents in clinical trials, just how they execute their effects is unclear. view more (2008-04-11)
Enzyme inhibitors block replication Of SARS virus
Researchers have known since 2003 that a site on the virus is responsible for mediating proteases that allow the virus to replicate. Since then researchers have been testing protease inhibitors to lock up this site, known as SARS 3CLpro, and effectively stop the virus from infecting additional cells in the body. view more (2006-03-28)
Study reveals how some molecules inhibit growth of lung cancer cells
By mapping the interlocking structures of small molecules and mutated protein "receptors" in non-small cell lung cancer (NSCLC) cells, scientists at Dana-Farber Cancer Institute and their colleagues have energized efforts to design molecules that mesh with these receptors, potentially interfering with cancer cell growth and survival. view more (2007-03-13)
Use of mon-COX-2-specific NSAIDs halves odds for oral cancer: doubles cardiovascular death risk
An analysis of 20 years of data on the health of over 900 adults has found that long-term use of traditional nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, cuts the risk for oral cancer in smokers by half. view more (2005-10-10)
Compounds could be new class of cancer drugs
A team of Vanderbilt University Medical Center investigators has developed a group of chemical compounds that could represent a new class of drugs for treating cancer. view more (2009-02-04)
Study Highlights Need For Improved Care Of Diabetes Patients In UK General Practice
Results of a UK study in this week's issue of THE LANCET highlight how people with diabetes controlled by diet alone have significant rates of complications and are less likely than patients on medication to be adequately monitored. Authors of the study conclude that there is great scope for the improved care of diabetic patients within UK general... view more... (2004-07-28)
Study identifies potential drug target for Huntington's disease
An enzyme known to be critical for the repair of damaged cells and the maintenance of cellular energy may be a useful target for new strategies to treat Huntington's disease (HD) and other disorders characterized by low cellular energy levels. view more (2006-07-31)
Switching immunosuppressants reduces cancer risk in kidney
Switching to a newer type of immunosuppressant drug may reduce the high rate of skin cancer after kidney transplantation, according to research being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, CA. view more (2009-11-02)
New research into the art of expression
New research, which could have far reaching implications for the teaching of art in schools, is set to be carried out at Staffordshire University. The Leverhulme Trust has awarded Staffordshire University £31,723 to examine what develops and why in British children`s expressive drawing. The research project is being undertaken by Dr Richard... view more... (2002-07-26)
Safety of antithrombotic treatment in acute coronary syndromes
The management of acute coronary syndromes (with or without ST segment elevation) requires the use of anticoagulants, antiplatelet agents (aspirin, clopidogrel and/or glycoprotein (GP) IIb/IIIa inhibitors), beta-blockers, thrombolytics in some cases, and revascularization / reperfusion. view more (2008-09-03)
U of I scientist develops enzyme inhibitor that may slow cancer growth
University of Illinois scientist Tim Garrow, in collaboration with Jiri Jiracek of the Czech Academy of Sciences, has applied for a provisional patent on a class of chemicals that has future therapeutic uses in medicine, specifically cancer treatment. view more (2006-07-07)
Weekly dose of osteoporosis drug prevents bone loss after breast cancer treatment
Breast cancer survivors who took a weekly dose of risedronate, sold as Actonel, lost significantly less bone than those who did not take the drug. view more (2007-09-19)
Homing in on blood pressure genes may lead to targeted therapy
For the first time, researchers have mapped a genetic location that explains why certain blood pressure-lowering drugs aren't effective for some people, according to researchers at the 2005 American Heart Association High Blood Pressure Research meeting. view more (2005-09-26)
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