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Crystallography Current Events | Crystallography News | 3
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Scripps Research scientists find early evolution maximized the 'spellchecking' of protein sequences
As letters of the alphabet spell out words, when amino acids are linked to one another in a particular order they "spell out" proteins. view more (2009-08-07)
Scripps scientists find structure of a protein that makes cancer cells resistant to chemotherapy
A research team at the Scripps Research Institute has obtained the first glimpse of a protein that keeps certain substances, including many drugs, out of cells. The protein, called P-glycoprotein or P-gp for short, is one of the main reasons cancer cells are resistant to chemotherapy drugs. Understanding its structure may help scientists design... view more... (2009-03-27)
Progress toward a new remedy for chronic urinary tract infections?
Researchers from the Flanders Interuniversity Institute for Biotechnology (VIB) at the Free University of Brussels have recently published results that show promise in the quest for a new remedy for chronic urinary tract infections. The researchers have shown that administration of the sugar Heptyl-a-D-mannoside can prevent E. coli bacteria from... view more... (2005-02-10)
First Look at an Enzyme Target for Antibacterial and Cancer Drugs
The veil has finally been lifted on an enzyme that is critical to the process of DNA transcription and replication, and is a prime target of antibacterial and anticancer drugs. view more (2007-12-21)
Work of Nobel-prize winning scientist Dorothy Hodgkin to be Celebrated with a Landmark Event at Oxford University
The work of the Nobel-prize winning crystallographer, Dorothy Hodgkin (1910-1994), which led to the synthesis of penicillin, vitamin B12 and insulin will be honoured by the Royal Society of Chemistry (RSC) at the University of Oxford on Monday 14 May 2001 through the designation of a National Historical Chemical Landmark. Dorothy Crowfoot Hodgkin... view more... (2001-05-10)
Media Invitation: 20 years of excellence - Catch-up on the latest news from ISIS and tour the facility
ISIS celebrates 20 years of excellence view more (2004-12-06)
Crystallography reveals the 3-D structure of mammalian sperm receptor
Scientists at the Swedish medical university Karolinska Institutet have determined the first 3D structure of ZP3, a protein essential for the interaction between the mammalian egg coat and sperm. view more (2008-12-05)
Structure of key enzyme in plague bacterium found
Researchers at the National Institute of Standards and Technology (NIST) have solved the structure of a key enzyme from the bacterium responsible for plague, finding that it has a highly unusual configuration. The results may shed light both on how the bacterium kills and on fundamental cell signaling processes. view more (2006-08-21)
CCLRC to play pivotal role in e-science
CCLRC (Council for the Central Laboratory of the Research Councils) welcomes the government's announcement today that offers extra funding for e-science. The extra £5 million over three years awarded to CCLRC will enable it to drive the development of e-science as a key technology for the next generation of major scientific facilities at the... view more... (2000-11-22)
Science news from BBSRC
These are just some of the research stories featured in the July 2001 issue of BBSRC business, the community magazine of the Biotechnology and Biological Sciences Research Council. Articles are available in full online at: www.bbsrc.ac.uk/news/features/current.html New chicken vaccine eliminates need for drug intake for broiler chickens A new... view more... (2001-07-02)
Mammoth project reveals frozen secrets
Which way does a mammoth skeleton point in Siberia? No, it’s not a Christmas cracker joke. To find the answer you have to look in a rather surprising place – the Institute of Physics’ new online archive. In an article published in the first edition of Proceedings of the Physical Society in 1874, John Rae writes about the... view more... (2003-01-08)
Researchers Create Model of Cancer-Preventing Enzyme, Study How It Works
Proline dehydrogenase is important because it plays a role in apoptosis, the process of cell death, by enabling the creation of superoxide, a highly reactive electron-rich oxygen species. view more (2007-05-14)
Structural polymorphism of 441-residue Tau at single residue resolution
Worldwide almost 30 million suffer from Alzheimer's disease, an irreversible, neurodegenerative condition that is eventually fatal. view more (2009-02-17)
Metal-containing compounds show promise as HIV weapon
A molecule consisting of two "cages" of metallic atoms bound to carbon has shown great promise in preliminary tests of becoming a new weapon in the anti-HIV arsenal, researchers at UT Southwestern Medical Center report. view more (2005-11-01)
Scientists learn structure of enzyme in unusual virus
Biologists have determined the three-dimensional structure of an unusual viral enzyme that is required in the assembly of new viruses. view more (2007-09-18)
Improved technique determines structure in membrane proteins
Understanding the form and function of certain proteins in the human body is becoming faster and easier, thanks to the work of researchers at the University of Illinois. view more (2008-08-18)
Iowa State University researchers discover structure of key Ebola protein
Research led by Iowa State University scientists has them a step closer to finding a way to counter the Ebola virus. view more (2009-01-13)
Discovery of the cell's water gate may lead to new cancer drugs
The flow of water into and out from the cell may play a crucial role in several types of cancer. Scientists at the University of Gothenburg have now found the gate that regulates the flow of water into yeast cells. view more (2009-06-17)
Newly described 'dragon' protein could be key to bird flu cure
Scientists and researchers have taken a big step closer to a cure for the most common strain of avian influenza, or "bird flu," the potential pandemic that has claimed more than 200 lives and infected nearly 400 people in 14 countries since it was identified in 2003. view more (2008-07-16)
Findings reveal how dengue virus matures, becomes infectious
Biologists at Purdue University have determined why dengue virus particles undergo structural changes as they mature in host cells and how the changes are critical for enabling the virus to infect new host cells. view more (2008-03-28)
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