Cystic Fibrosis Current Events | Cystic Fibrosis News | 11
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First mouse lung transplants lay groundwork for new ways to prevent transplant rejection in humans
Lung transplants have been performed successfully for more than 20 years in humans but never before in mice - until now. view more (2007-07-12)
Is endotoxin receptor CD14 rs2569190/C-159T gene correlated with chronic hepatitis C?
It is still unknown why the natural history of chronic disease caused by hepatitis C virus (HCV), which currently infects 3% of the world's population, varies from mild in some patients to rapidly progressing in others. view more (2009-08-27)
Consortium develops new method to manipulate genetic material
A multi-institutional team of researchers, including scientists at the University of Minnesota Medical School, have developed a powerful tool for genomic research and medicine. view more (2008-07-25)
Jefferson scientists uncover new clues to how crucial molecular gatekeepers work
One of the biggest mysteries in molecular biology is exactly how ion channels - tiny protein pores through which molecules such as calcium and potassium flow in and out of cells - operate. view more (2005-10-12)
Bioinformatics technology developed at Argonne provides new insight into microbial activities
Scientists may gain a new insight into the relationship between viruses and their environments thanks to a new computational technology developed by researchers at the U.S. Department of Energy's (DOE) Argonne National Laboratory. This technology has already been used to identify subtle differences in the metabolic processes of microbial... view more... (2008-03-17)
Nanoparticle treatment for burns curbs infection, reduces inflammation
Treating second-degree burns with a nanoemulsion lotion sharply curbs bacterial growth and reduces inflammation that otherwise can jeopardize recovery, University of Michigan scientists have shown in initial laboratory studies. view more (2009-09-15)
Gene therapy accelerates healing of damaged skeletal muscle
University of Pittsburgh School of Medicine researchers have successfully used gene therapy to accelerate muscle regeneration in experimental animals with muscle damage, suggesting this technique may be a novel and effective approach for improving skeletal muscle healing, particularly for serious sports-related injuries. view more (2006-06-05)
Attention: Extra-hepatic manifestation of hepatitis C virus infection
In 1994, the team of Tchernev and Petrova from Alexandrovska Hospital in Sofia examined a female patient with liver cirrhosis caused by chronic Hepatitis C virus (HCV). view more (2008-01-17)
First high-res 3D structures of mammalian HSP90 protein solved
Dr. Dan Gewirth, Hauptman-Woodward senior research scientist, has just solved the structure of the first mammalian GRP94 protein implicated in immune diseases such as sepsis, AIDS and certain cancers. view more (2007-10-15)
Is transforming growth factor-beta involved in intestinal wound healing?
Migration of colonic lamina propria fibroblasts (CLPF) plays an important role during the progression of fibrosis and fistulae in Crohn's disease. Transforming growth factor- beta (TGF- beta) is involved in the regulation of cell migration, cell differentiation, extracellular matrix deposition, and immune responses. view more (2009-03-31)
Scientists reveal fine detail of cell`s energy machinery
A molecular pump that helps to keep cells flush with energy has been visualised by scientists at Imperial College, London. The structure of the pump, a key enzyme in bacterial respiration, reveals for the first time one of the molecular mechanisms that underpins cellular respiration, and confirms a Nobel Prize-winning theory proposed over 40... view more... (2002-03-05)
ISU researchers find possible treatment for Spinal Muscular Atrophy
Spinal Muscular Atrophy is the second-leading cause of infant mortality in the world. view more (2009-07-28)
Bacterial toxin closes gate on immune response, Penn researchers discover
Researchers at the University of Pennsylvania School of Medicine have demonstrated that a bacterial toxin from the common bacterium Staphylococcus aureus shuts down the control mechanism of the tunnel, called an ion channel, in immune cell membranes. view more (2008-02-14)
The importance of gene regulation for common human disease
A new study published in Nature Genetics on Sunday 16 September 2007 show that common, complex diseases are more likely to be due to genetic variation in regions that control activity of genes, rather than in the regions that specify the protein code. view more (2007-09-17)
'Conversation stoppers' fight deadly bacterial infections
Bacterial infections are becoming more deadly worldwide due to increased resistance to antibiotics. Now, chemists at the University of Wisconsin-Madison have developed a powerful strategy to fight these deadly infections: Instead of killing the bacteria directly, the scientists designed a group of compounds that can block the chemical signals that... view more... (2006-09-11)
Causative gene of a rare disorder discovered by sequencing only protein-coding regions of genome
For the first time, scientists have successfully used a method called exome sequencing to quickly discover a previously unknown gene responsible for a mendelian disorder. view more (2009-11-20)
Skin care: new research into scar-free healing
New research from the University of Bristol shows that by suppressing one of the genes that normally switches on in wound cells, wounds can heal faster and reduce scarring. This has major implications not just for wound victims but also for people who suffer organ tissue damage through illness or abdominal surgery. view more (2008-01-21)
U study shows MRI-based method holds promise for predicting treatment outcomes in patients with AF
University of Utah researchers have found that delayed-enhancement magnetic resonance imaging (DE-MRI) holds promise for predicting treatment outcomes and measuring disease progression for patients with atrial fibrillation (AF), a little known heart rhythm disorder that affects more than 3.5 million Americans and causes more than 66,000 deaths a... view more... (2009-04-08)
Smoking belies milder disease but worse prognosis for IPF patients
Smokers and ex-smokers with idiopathic pulmonary fibrosis (IPF), an untreatable progressive lung disease that usually leads to death within a few years of diagnosis, have a worse prognosis than non-smokers, according to research from London. view more (2008-01-15)
White blood cells in lung produce histamine seen in allergies
In a surprise finding, scientists have discovered that histamine, the inflammatory compound released during allergic reactions that causes runny nose, watery eyes, and wheezing, can be produced in large amounts in the lung by neutrophils, the white blood cells that are the major component of pus. view more (2007-01-15)
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