Cystic Fibrosis Current Events | Cystic Fibrosis News | 3
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Cystic Fibrosis Foundation announces positive early results for phase 2 clinical trial of VX-770
The Cystic Fibrosis Foundation announced today that VX-770, an oral drug in development that targets a basic defect in CF, showed promising results in an ongoing Phase 2a clinical trial for patients who carry the G551D mutation of CF. The drug is being developed by Vertex Pharmaceuticals Incorporated. view more (2008-03-28)
Deficiency in the protein MBL2 linked to increased cystic fibrosis severity
Cystic fibrosis (CF), a hereditary disorder causing thick mucous production and frequent lung infections, is associated with a high mortality rate primarily due to lung failure. view more (2008-02-22)
Cystic fibrosis clinical study patients show less lung function decline
Although cystic fibrosis patients in clinical trials had more severe illness, worse lung function, a lower weight level and more respiratory infection than non-participants, their involvement in research studies resulted in less lung function decline over a 7-year period. view more (2006-01-03)
Research Matters at the Arizona Health Sciences Center (AHSC): UA Researchers Seek Safer Cystic Fibrosis Test
Researchers from The University of Arizona Colleges of Pharmacy and Medicine are teaming up to try to invent a novel non-invasive lung test for cystic fibrosis sufferers. view more (2009-09-10)
UF study sheds light on cystic fibrosis-related diabetes
A growing number of cystic fibrosis patients are battling a second, often deadly complication: a unique form of diabetes that shares characteristics of the type 1 and type 2 versions that strike many Americans. view more (2006-07-07)
Ibuprofen associated with slower lung function decline in children with cystic fibrosis
Treatment with ibuprofen is associated with a significantly slower rate of decline in lung function in children and adolescents with cystic fibrosis, according to a new study. view more (2007-11-30)
Newly discovered proteins associated with cystic fibrosis
Researchers have found a highly unusual distribution of two proteins in the lungs and airways of people with cystic fibrosis, a discovery that could be a step in determining how the disease progresses. view more (2006-11-03)
Mutation responsible for cystic fibrosis also involved in muscle atrophy
Patients with cystic fibrosis (CF) usually experience significant muscle loss, a symptom traditionally considered to be a secondary complication of the devastating genetic disease. view more (2009-07-31)
Researchers discover cell's 'quality control' mechanism
Researchers in Japan and Canada have discovered a key component of the quality control mechanism that operates inside human cells - sometimes too well. The breakthrough has significant implications for the development of new treatments for cystic fibrosis (CF) and some other hereditary diseases, the researchers say. Their results were published... view more... (2008-07-30)
Once-daily cystic fibrosis drug offers simpler home treatment and fewer side effects for children, study shows
Nottingham researchers have found a way to treat children with cystic fibrosis (CF), which could reduce their side effects and see more young patients treated at home. view more (2005-02-09)
Cystic fibrosis patients may breathe easier, thanks to bioengineered antimicrobials
By better understanding how antimicrobials bind and thereby get inactivated in the mucus of air passages, researchers at the University of Illinois may have found a way to help cystic fibrosis patients fight off deadly infections. view more (2007-09-25)
Bacteria in disguise cause problems for cystic fibrosis sufferers
Bacteria that cause infections in the lungs of cystic fibrosis patients avoid detection by changing their appearance according to Cardiff University researchers speaking today, Thursday 13 September 2001, at the bi-annual meeting of the Society for General Microbiology at the University of East Anglia. "Pseudomonas aeruginosa bacteria, which... view more... (2001-08-31)
Cystic Fibrosis Proteins Photographed Interacting
New microscopic pictures show the first-ever physical evidence of interaction between two proteins involved in Cystic Fibrosis (CF) disease. view more (2007-12-10)
Nanoemulsion potent against superbugs killing cystic fibrosis patients
University of Michigan scientists report highly encouraging evidence that a super-fine oil-and-water emulsion, already shown to kill many other microbes, may be able to quell the ravaging, often drug-resistant infections that cause nearly all cystic fibrosis deaths. view more (2009-02-05)
UC research discovers new way to fight antibiotic-resistant bacteria
Research by a team at the University of Cincinnati (UC) has helped in the discovery of a new way to fight antibiotic-resistant bacteria, responsible for preventing treatment of lung infections in patients with cystic fibrosis and life-threatening cases of pneumonia. view more (2007-03-19)
Rattlesnake-type poisons used by superbug bacteria to beat our defenses
Colonies of hospital superbugs can make poisons similar to those found in rattlesnake venom to attack our bodies' natural defences, scientists heard today (Monday 8 September 2008) at the Society for General Microbiology's Autumn meeting being held this week at Trinity College, Dublin. view more (2008-09-08)
Researchers identify molecule that causes destructive lung inflammation in cystic fibrosis patients
Scientists at Children's Hospital of Pittsburgh of UPMC have identified a protein that is critical to the development of inflammation during lung infection in patients with cystic fibrosis (CF). view more (2006-11-07)
Peptide discovered in scorpion venom may hold key to secretory diseases
Researchers have discovered a peptide in scorpion venom that may hold the key to understanding and controlling cystic fibrosis and other secretory diseases. view more (2008-02-15)
Newborns with respiratory distress potentially have rare genetic disease
Newborns with respiratory distress should be evaluated for primary ciliary dyskinesia, a rare genetic disease that has features similar to cystic fibrosis, says Thomas Ferkol, M.D., from Washington University School of Medicine in St. Louis. view more (2007-02-21)
Children with cystic fibrosis not well covered by guidelines for vitamin D needs
Existing recommendations for treating vitamin D deficiency in children with cystic fibrosis (CF) are too low to cover the serious need, leaving most at high risk for bone loss and rickets, according to researchers at Johns Hopkins Children's Center. view more (2008-10-10)
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