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Cystic Fibrosis Current Events | Cystic Fibrosis News | 6

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UCSF marks a milestone with 500th transplant in heart and lung program
UCSF marked a milestone this week with the 500th procedure in its Thoracic Transplant Program, which specializes in transplantation of the heart and lung.   view more (2008-04-25)

Are bone marrow mononuclear cells effective in reducing hepatic lesions?
Liver fibrosis occurs in the setting of chronic injury caused by different etiologies constituting a serious worldwide public health problem. In addition to schistosomiasis, hepatopathies due to alcohol, viral hepatitis, drugs, metabolic and autoimmune diseases, and congenital abnormalities are important causes of liver fibrosis.   view more (2008-10-24)

Scientists identify novel way to prevent cardiac fibrosis
In a study that points to a new strategy for preventing or possibly reversing fibrosis - the scarring that can lead to organ and tissue damage - researchers at the University of California, San Diego School of Medicine have determined that a molecule called Epac (Exchange protein activated by cAMP1), plays a key role in integrating the body's pro-... view more... (2008-04-23)

Against pulmonary fibrosis
The biotech companies Digna Biotech and Biotherapix have signed an agreement to jointly apply their patented products towards the development of a treatment for pulmonary fibrosis.   view more (2006-03-06)

Congenital heart disease increasingly more common in adults, children
The prevalence of congenital heart disease (CHD) has increased strikingly in adults and children in a new population study, researchers reported in Circulation: Journal of the American Heart Association.   view more (2007-01-09)

Cystic fibrosis research could benefit from multi-functional sensing tool
Researchers are using an innovative, multi-functional sensing tool to investigate adenosine triposphate (ATP) release and its role in cystic fibrosis.   view more (2006-03-27)

Fistula-related morbidity decreased by prompt treatment in Sierra Leone
Extent of fibrosis is the most profound factor in predicting surgical outcomes of genitourinary fistula repair, suggesting that prompt treatment could significantly improve survival.   view more (2009-04-27)

Noninvasive tests for cirrhosis may help to avoid liver biopsy
Newer ultrasound and magnetic resonance (MR) imaging tests yield encouraging initial results in diagnosing fibrosis (scarring) and cirrhosis of the liver, according to three studies in the October issue of the journal Clinical Gastroenterology and Hepatology.   view more (2007-10-02)

Viagra for alleviation of pulmonary hypertension?
Results of a preliminary study in this week's issue of THE LANCET suggest that Viagra may have a future role in the treatment of pulmonary hypertension (increased blood pressure in the pulmonary artery), a severe and potentially fatal condition causing respiratory impairment. Lung fibrosis (scarring of the lungs due to inflammation of the... view more... (2002-09-18)

Even at High Doses, Gadolinium-Based Contrast Agents Cannot by Themselves Cause Patients to Develop Nephrogenic Systemic Fibrosis
Even at very high doses, gadolinium-based contrast agents alone are not sufficient to cause nephrogenic systemic fibrosis (NSF) in patients with kidney problems.   view more (2009-07-01)

Test predicts risk of liver scarring after transplant, study shows
An estimated 20 percent of people with chronic hepatitis C who receive a liver transplant will develop advanced cirrhosis, scarring of the new organ severe enough to impair its ability to function normally within five years of transplantation.   view more (2005-10-06)

MRC mouse research centre to understand the role of genes in disease opened by Lord Sainsbury today
A new £18M Medical Research Council (MRC) facility to understand and compare the genetics of disease in mice and humans will be opened today, Wednesday 30 June, by Lord Sainsbury, Minister for Science and Technology. The Mary Lyon Centre, at Harwell, Oxfordshire, headed by professor Bob Johnson, will primarily support research carried out at... view more... (2004-06-29)

No hiding place for infecting bacteria
Scientists in Colorado have discovered a new approach to prevent bacterial infections from taking hold. Writing in the Journal of Medical Microbiology, Dr Quinn Parks and colleagues describe how they used enzymes against products of the body's own defence cells to prevent Pseudomonas aeruginosa bacteria from building a protective biofilm which... view more... (2009-03-16)

Primary care practitioners need to become genetically literate
Increasing availability of DNA based tests and demand by patients for genetic information and advice mean that primary care practitioners will need to become genetically literate. A paper in this week's BMJ discusses the implications of genetic advances for primary care. Currently, the most important elements for primary care are prediction of... view more... (2001-04-24)

Probe position may change results in liver stiffness measurements in transient elastography
A major clinical challenge is to find the best method to evaluate and to manage the increasing numbers of patients with chronic liver disease. Liver biopsy, due to its risks and limitations, is no longer considered mandatory as the first-line indicator of liver injury, and several markers have been developed as non-invasive alternatives.   view more (2009-07-29)

A potential therapeutic agent for hepatic fibrosis
Accumulating evidence suggests that connective tissue growth factor (CCN2) plays a central role in fibrotic conditions in many organ systems.   view more (2009-08-26)

Tobacco Smoke and Alcohol Harm Liver Worse as Combo
Exposure to second-hand smoke and alcohol significantly raises the risk of liver disease, according to researchers at the University of Alabama at Birmingham (UAB).   view more (2009-02-04)

Listening to chronically ill children
Chronically ill children want teachers to understand the effects of their condition on school life. They worry about keeping up with school work and being left out of school activities. These findings come from a study by Ms Suzanne Wright and Mrs Jane Lightfoot, Social Policy Research Unit, University of York and were presented today, Tuesday 15... view more... (1998-12-03)

High blood pressure causes pathological scars in the heart
Fibrosis (scar tissue formation) is the determinant lesion in the subsequent evolution of the heart in a patient with high blood pressure. This item appeared in the latest edition of Nature Clinical Practice Cardiovascular Medicine, a journal that is part of the Nature group. The article published heart research recently carried out at the... view more... (2005-05-25)

Case researcher in RNA biology makes waves by challenging current thinking
In the January 18th issue of Molecular Cell, Case Western Reserve University School of Medicine researcher Kristian E. Baker, Ph.D. challenges molecular biology's established body of evidence and widely-accepted model for nonsense-mediated messenger ribonucleic acid (mRNA) decay.   view more (2008-01-21)
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