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Nanoparticle Assembly Enters the Fast Lane The speed of nanoparticle assembly can be accelerated with the assistance of the molecule that carries life's genetic instructions, DNA, a team of researchers at the U.S. Department of Energy's Brookhaven National Laboratory recently found. view more (2006-10-12)
Gladstone investigators identify a new protective action for the powerful anti-HIV factor, APOBEC3G Scientists at the Gladstone Institute of Virology and Immunology (GIVI) have identified a previously unknown function of APOBEC3G (A3G), a protein that acts against HIV, a finding that may lead to new approaches for controlling HIV infection. view more (2006-10-03)
First molecular simulation of a long DNA strand shows unexpected flexibility It turns out that sequencing the human genome - determining the order of DNA building blocks - has not completely cracked the code of how DNA directs various cellular processes. In addition to the sequence of the base pairs, the instructions are in the packaging - how DNA is folded within a cell. view more (2006-12-07)
Viral marker of human migration suspect A benign virus previously used as a marker in tracing human migration may be unreliable. view more (2006-10-25)
Phoenix rising: Scientists resuscitate a 5 million-year-old retrovirus A team of scientists has reconstructed the DNA sequence of a 5-million-year-old retrovirus and shown that it is able to produce infectious particles. view more (2006-10-31)
Low-cost Parkinson's disease diagnostic test a world first Scientists at Melbourne 's Howard Florey Institute have developed a cost-effective diagnostic test for Parkinson's disease (PD), which will also assist researchers to understand the genetic basis of PD and to undertake large-scale studies to identify the genes that cause this debilitating condition. view more (2007-02-26)
DNA computing targets West Nile Virus, other deadly diseases Researchers say that they have developed a DNA-based computer that could lead to faster, more accurate tests for diagnosing West Nile Virus and bird flu. view more (2006-10-17)
In a technical tour de force, Salk scientists take a global view of the epigenome A collaboration between researchers at the Salk Institute for Biological Studies and the University of California at Los Angeles captured the genome-wide DNA methylation pattern of the plant Arabidopsis thaliana-the "laboratory rat" of the plant world-in one big sweep. view more (2006-09-01)
Ring-like formations in drying DNA drops could affect hybridization studies Coffee drinkers are familiar with the ring-shaped stains that result from spilled drops that have dried, in which the brown stain is not evenly distributed, but instead concentrated at the edge. view more (2006-05-12)
Molecular markers signal early metastases from ocular melanoma Patients with melanoma of the eye are at risk for liver metastases, which are often not detected until they have turned into large, lethal tumors. view more (2006-09-14)
Few clues about African ancestry to be found in mitochondrial DNA Mitochondrial DNA may not hold the key to your origins after all. A study published today in the open access journal BMC Biology reveals that fewer than 10% of African American mitochondrial DNA sequences analysed can be matched to mitochondrial DNA from one single African ethnic group. view more (2006-10-12)
From a lowly yeast, researchers divine a clue to human disease Working with a common form of brewer's yeast, University of Wisconsin-Madison researchers have uncovered novel functions of a key protein that allow it to act as a master regulatory switch - a control that determines gene activity and that, when malfunctioning in humans, may contribute to serious neurological disorders. view more (2006-12-08)
Nanotech tools yield DNA transcription breakthrough Rutgers researcher Richard H. Ebright and his collaborators have resolved key questions regarding transcription, the fundamental life process that was the subject of the 2006 Nobel Prize in Chemistry. view more (2006-11-17)
Powerful genome ID method extended to humans A mathematical discovery has extended the reach of a novel genome mapping method to humans, potentially giving cancer biology a faster and more cost-effective tool than traditional DNA sequencing. view more (2006-10-10)
Novel regulatory mechanism identified for key tumor suppressor p53 Collaborating scientists from The Wistar Institute in Philadelphia and The Vienna Biocenter in Austria have identified a novel mechanism involved in normal repression of the p53 protein, perhaps the single most important molecule for the control of cancer in humans. view more (2006-11-16)
Researchers shed light on shrinking of chromosomes A human cell contains an enormous 1.8 metres of DNA partitioned into 46 chromosomes. view more (2007-06-12)
Child abuse may 'mark' genes in the brains of suicide victims A team of McGill University scientists has discovered important differences between the brains of suicide victims and so-called normal brains. Although the genetic sequence was identical in the suicide and non-suicide brains, there were differences in their epigenetic marking - a chemical coating influenced by environmental factors. view more (2008-05-07)
Single molecular 'mark' seen as pivotal for genome compaction in spores and sperm In higher order animals, genetic information is passed from parents to offspring via sperm or eggs, also known as gametes. In some single-celled organisms, such as yeast, the genes can be passed to the next generation in spores. view more (2006-09-18)
Fungi can tell us about the origin of sex chromosomes Fungi do not have sexes, just so-called mating types. A new study being published today in the prestigious journal PLoS shows that there are great similarities between the parts of DNA that determine the sex of plants and animals and the parts of DNA that determine mating types in certain fungi. view more (2008-03-18)
Bioportfolio: Life-long persistence of erythrovirus DNA genomes in human tissue The researchers at the University of Helsinki, Finland, and University Hospital of Bonn, Germany, have coined the novel term "Bioportfolio" to describe viral genomic material remaining in the human body after infection. view more (2006-04-26)
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