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Large DNA microarray dataset is made publicly available by LGC and the European Bioinformatics Institute (EBI)
As the next phase of DTI's Measurements for Biotechnology (MfB) programme to 2007 gets underway, a large DNA microarray dataset generated by an LGC-led consortium during the first phase is now freely available online at ArrayExpress, a leading public repository managed by the European Bioinformatics Institute (EBI). The sharing of well-annotated... view more... (2005-02-17)
Heme controls antioxidants and iron in ferritin
More than one million Americans have abnormal iron levels in their bodies. For example, iron excess can lead to a long list of health problems including diabetes, heart failure, liver cancer, arthritis and severe fatigue. view more (2005-10-11)
Nanotechnology innovation may revolutionize gene detection in a single cell
Scientists at Arizona State University's Biodesign Institute have developed the world's first gene detection platform made up entirely from self-assembled DNA nanostructures. view more (2008-01-11)
DOE JGI sequences DNA from extinct cave bear
The genomic DNA sequencing of an extinct Pleistocene cave bear species-the kind of stuff once reserved for science fiction-has been logged into scientific literature thanks to investigators from the U.S. Department of Energy (DOE) Joint Genome Institute (JGI). view more (2005-06-03)
UNC scientists discover cellular 'SOS' signal in response to UV skin damage
New research from the University of North Carolina at Chapel Hill School of Medicine has identified two proteins that may help protect against skin cancer. view more (2007-03-19)
FISH-ing for links between cancer and aging
Wielding a palette of chromosome paints, scientists at the Salk Institute for Biological Studies have taken a step closer to understanding the relationship between aging and cancer by visualizing chromosomes of cells from patients with a heritable premature aging disease known as Werner Syndrome. view more (2007-02-06)
Investigating the invisible life in our environment
Microorganisms make up more than a third of the Earth's biomass. They are found in water, on land and even in our bodies, recycling nutrients, influencing the planet's climate or causing diseases. view more (2007-02-02)
FSU chemists using light-activated molecules to kill cancer cells
A key challenge facing doctors as they treat patients suffering from cancer or other diseases resulting from genetic mutations is that the drugs at their disposal often don't discriminate between healthy cells and dangerous ones -- think of the brute-force approach of chemotherapy, for instance. view more (2007-08-09)
Search for the 'on' switches may reveal genetic role in development and disease
A new resource that identifies regions of the human genome that regulate gene expression may help scientists learn about and develop treatments for a number of human diseases, according to researchers at Duke's Institute for Genome Sciences & Policy (IGSP). view more (2008-01-25)
2 heads are better than 1: 2 dysfunctional DNA repair pathways kill tumor cells
Individuals who inherit two mutant copies of any one of about 12 genes that make the proteins of the Fanconi Anemia (FA) pathway develop FA, which is characterized by increased incidence of cancer and bone marrow failure, among other things. view more (2007-04-13)
New gene associated with Fanconi anemia 'explains' hallmark chromosomal instability
Surprising findings from just five patients has led to the first proof of how the rare disorder Fanconi anemia causes chromosomal instability. view more (2005-08-22)
Epigenetics to shape stem cell future
Everyone hopes that one day stem cell-based regenerative medicine will help repair diseased tissue. view more (2007-02-20)
New Bacteria Test Could Improve Quality of Fruit and Vegetable Juice
Increasingly, consumer products, especially food and beverage products, are being scrutinized for better quality. view more (2007-05-10)
New study shows how genetic repair mechanism helps seal DNA breaks
As the genetic material, DNA is surprisingly reactive and under continuous assault from environmental toxins and reactive cellular metabolites, so a means of repairing DNA damage is essential to maintaining the integrity of our genetic blueprint for future generations. view more (2006-10-23)
Environmental triggers may promote human genetic variation
In this month's issue of the leading scientific journal Genome Research, scientists from Kyushu University report how environmentally damaged DNA may contribute to human genetic diversity. view more (2006-05-01)
Researchers make synthetic DNA 'barcodes' to tag pathogens, providing an inexpensive, off-the-shelf monitoring system
A supermarket checkout computer can identify thousands of different items by scanning the tiny barcode printed on the package. New technology developed at Cornell University could make it just as easy to identify genes, pathogens, illegal drugs and other chemicals of interest by tagging them with color-coded probes made out of synthetic... view more... (2005-06-14)
Ancient Etruscans unlikely ancestors of modern Tuscans, statistical testing reveals
For the first time, Stanford researchers have used novel statistical computer modeling to simulate demographic processes affecting the population of Tuscany over a 2,500-year time span. Rigorous tests used by the researchers have ruled out a genetic link between ancient Etruscans, the early inhabitants of central Italy, and the region's modern day... view more... (2006-05-26)
Cigarette smoke alters DNA in sperm, genetic damage could pass to offspring
The science has long been clear that smoking causes cancer, but new research shows that children could inherit genetic damage from a father who smokes. view more (2007-06-01)
High-throughput oncogene mutation detection in human cancers by mass spectrometry-based genotyping
Researchers have devised a new method to detect a spectrum of known gene mutations in a variety of cancer genes that they say is both sensitive and cost-effective. view more (2006-09-14)
The muskox suffered a loss of genetic diversity at the Pleistocene/Holocene transition
The tundra muskox, one of the few large northern mammals to have survived to the present day, saw its genetic diversity decrease greatly at the end of the Pleistocene period, around 10,000 years ago. view more (2005-10-06)
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