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Carbon nanotubes that detect disease-causing mutations developed by Pitt researcher
University of Pittsburgh researcher Alexander Star and colleagues at California-based company Nanomix, Inc., have developed devices made of carbon nanotubes that can find mutations in genes causing hereditary diseases.   view more (2006-01-26)

DNA repair in mammal embryos is a matter of timing
Investigators at St. Jude Children's Research Hospital have discovered that the cells of the developing nervous system of the mammalian embryo have an exquisite sense of timing when it comes to fixing broken chromosomes: the cells use one type of repair mechanism during the first half of development and another during the second half.   view more (2006-06-20)

Targeting the dosage compensation complex
Three independent research papers in the April 1 issue of G&D detail the chromosome-wide binding of the Drosophila dosage compensation complex (DCC) to the single male X chromosome, shedding new light on the mechanism of DCC targeting.   view more (2006-03-17)

Public collections of DNA and RNA sequence reach 100 gigabases
The world's three leading public repositories for DNA and RNA sequence information have reached 100 gigabases [100,000,000,000 bases; the 'letters' of the genetic code] of sequence.   view more (2005-08-23)

Using the genomic shortcut to predict bacterial behavior
How do you study a pathogen that can't survive outside its host's cells? In a new study published in the open access journal PLoS Biology, Hiroyuki Ogata and colleagues show that sequencing and analyzing the genome of the bacteria Rickettsia felis provide valuable insights into the biology and behavior of this intracellular pathogen.   view more (2005-07-05)

Normal chromosome ends elicit a limited DNA damage response
Researchers at the Salk Institute for Biological Studies discovered that cells co-opted the machinery that usually repairs broken strands of DNA to protect the integrity of chromosomes.   view more (2005-11-28)

Enzyme crystal structure reveals 'unexpected' genome repair functions
The research looked at XPB helicase from an archaea, a single cell organism similar to bacteria. Helicases are enzymes that unwind or separate the strands of the nucleic acid double helix, an action that is critical to transcription and nucleotide excision repair (NER), as well as other cell processes.   view more (2006-04-07)

Cancer cells suppress large regions of DNA by a reversible process that can be tackled
Cancer researchers at Sydney's Garvan Institute, in collaboration with Spanish scientists, have formulated a new concept for how cancer cells can escape normal growth controls, which may have far-reaching implications for the new generation of cancer therapies.   view more (2006-04-24)

DNA 'tattoos' link adult, daughter stem cells in planarians
Unlike some parents, adult stem cells don't seem to mind when their daughters get a tattoo. In fact, they're willing to pass them along.   view more (2008-09-11)

Rules to Target RNA Are Focus of Research
Once described as DNA's less-famous chemical cousin, RNA, or ribonucleic acid, recently has moved to center stage.   view more (2005-12-19)

Scientists Uncover Rules for Gene Amplification
Gene amplification plays an important role in causing cancers via activation of oncogenes.   view more (2006-06-30)

MIT's nanoprinter could mass-produce nano-devices
Just as the printing press revolutionized the creation of reading matter, a "nano-printing" technique developed at MIT could enable the mass production of nano-devices currently built one at a time.   view more (2005-06-08)

Nano machine switches between biological and silicon worlds
Scientists have created a molecular switch that could play a key role in thousands of nanotech applications. The Mol-Switch project successfully developed a demonstrator to prove the principle, despite deep scepticism from specialist colleagues in biotechnology and biophysics.   view more (2006-04-25)

Innocuous intestinal bacteria may be reservoir for resistance
"Harmless" bacteria in the digestive tracts of dairy cows, may not be so harmless after all. They may be a reservoir for antibiotic resistance genes that can be transferred to more harmful, disease-causing bacteria.   view more (2006-05-25)

Researchers Identify Human DNA on the Fast Track
Since completing the sequencing of the chimpanzee genome last year, geneticists have spent many hours comparing human DNA sequences to those of our closest evolutionary relative, looking for the differences that distinguish the two species.   view more (2006-08-17)

Faulty gene linked to prostate cancer risk
Missing sections of a gene, which programmes the manufacture of a chemical to alert the body to DNA damage.   view more (2006-10-31)

Researchers test reliability of forensic DNA technology in fight against crime
Researchers from Barts and The London, Queen Mary`s School of Medicine and Dentistry are to team up with colleagues from universities in Germany, Spain and Denmark in a £1m European research collaboration to test DNA techniques used to solve crime. DNA is often used by forensic scientists to identify persons from physical evidence left... view more... (2002-07-26)

DNA gets new twist: Carnegie Mellon scientists develop unique 'DNA nanotags'
Carnegie Mellon University scientists have married bright fluorescent dye molecules with DNA nanostructure templates to make nanosized fluorescent labels that hold considerable promise for studying fundamental chemical and biochemical reactions in single molecules or cells.   view more (2007-01-29)

DNA self-assembly used to mass-produce patterned nanostructures
Duke University scientists have used the self-assembling properties of DNA to mass-produce nanometer-scale structures in the shape of a 4x4 grids, on which patterns of molecules can be specified.   view more (2005-12-23)

Boston University scientists develop new application to characterize structure of DNA molecules
A team of researchers from Boston University has developed a new application to enable more precise measurement of the location of a fluorescent label in a DNA layer.   view more (2006-03-01)
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