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Gene-bender proteins may sway to DNA
Among the many genes packed into each cell of our body, those that get turned on, or expressed, are the ones that make us who we are. Certain proteins do the job of regulating gene expression by clasping onto key spots of DNA - the nucleic acid that contains the genetic instructions. view more (2006-12-05)
DNA gets new twist: Carnegie Mellon scientists develop unique 'DNA nanotags'
Carnegie Mellon University scientists have married bright fluorescent dye molecules with DNA nanostructure templates to make nanosized fluorescent labels that hold considerable promise for studying fundamental chemical and biochemical reactions in single molecules or cells. view more (2007-01-29)
Cancer is a stem cell issue
There is an urgent reason to study stem cells: stem cells are at the heart of some, if not all, cancers. view more (2007-02-20)
Probability Controls The Molecule Of Life
Thanks to biophysicists, statistics has reached the most intimate aspect of life - regulation of genes' activity. Investigation on probabilistic aspects of molecular biology has been supported by the Russian Foundation for Basic Research and the INTAS Foundation. Regulation of genes' activity is one of the most important biological problems which... view more... (2004-05-24)
NIAID DNA vaccine for H5N1 avian influenza enters human trial
The first human trial of a DNA vaccine designed to prevent H5N1 avian influenza infection began on December 21, 2006, when the vaccine was administered to the first volunteer at the National Institutes of Health (NIH) Clinical Center in Bethesda, MD. view more (2007-01-05)
DNA self-assembly used to mass-produce patterned nanostructures
Duke University scientists have used the self-assembling properties of DNA to mass-produce nanometer-scale structures in the shape of a 4x4 grids, on which patterns of molecules can be specified. view more (2005-12-23)
Researchers identify gene as protector of DNA, enemy of tumors
A single gene plays a pivotal role launching two DNA damage detection and repair pathways in the human genome, suggesting that it functions as a previously unidentified tumor suppressor gene. view more (2006-08-07)
HPV testing a cost-effective strategy for women with equivocal cervical screening results
A new study has found that using human papillomavirus (HPV) DNA testing to determine who should receive a cervical examination called colposcopy is a cost-effective management strategy for women with equivocal Pap test results known as ASCUS (atypical squamous cells of undetermined significance). view more (2006-01-18)
Ebola DNA vaccine produces immune responses in all fully vaccinated volunteers in Phase 1 trial
Vical Incorporated (Nasdaq:VICL) announced today that an Ebola vaccine candidate administered using Vical's proprietary DNA delivery technology was safe and well tolerated, and produced both antibody and T-cell Ebola-specific responses in all healthy volunteers who received the full 3 doses of vaccine. view more (2006-02-22)
Boston University scientists develop new application to characterize structure of DNA molecules
A team of researchers from Boston University has developed a new application to enable more precise measurement of the location of a fluorescent label in a DNA layer. view more (2006-03-01)
Johns Hopkins researchers find link between cell's energy use and genome health
While studying how a cell keeps its genetic material intact, scientists at Johns Hopkins got busy alternately knocking out two catalysts vital to managing a yeast cell's energy. view more (2006-07-24)
Links between DNA damage and breast cancer studied
Researchers from the Pacific Northwest Research Institute (PNRI) and the National Institute of Standards and Technology (NIST) have uncovered a pattern of DNA damage in connective tissues in the human breast that could shed light on the early stages of breast cancer and possibly serve as an early warning of a heightened risk of cancer. view more (2006-08-07)
Insignia -- A new way to identify viruses and bacteria
Now that the genome sequences of hundreds of bacteria and viruses are known, we can design tests that will rapidly detect the presence of these species based solely on their DNA. view more (2007-05-18)
Computational model simulates AZT metabolism in mitochondria
Researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech have developed a computational model that allows scientists to better understand the metabolism and toxicity of the HIV/AIDS drug zidovudine (azidothymidine, AZT). view more (2006-07-25)
New role for gene that counteracts formation of tumors
The researchers, connected to Ghent University, have discovered the function of an important mediator involved in suppressing the development of tumors. view more (2005-08-26)
Neandertals, humans share key changes to 'language gene'
A new study published online on October 18th in Current Biology reveals that adaptive changes in a human gene involved in speech and language were shared by our closest extinct relatives, the Neandertals. view more (2007-10-19)
Brown Engineers Use DNA to Direct Nanowire Assembly and Growth
A research team led by Brown University engineers has harnessed the coding power of DNA to create zinc oxide nanowires on top of carbon nanotube tips. The feat, detailed in the journal Nanotechnology, marks the first time that DNA has been used to direct the assembly and growth of complex nanowires. view more (2006-07-17)
Two More Potential HIV Vaccines
Despite long-term researchers' efforts, efficient human immunodeficienct virus (HIV) vaccine has not been created yet. However, researchers are not giving up their attempts. Russian biologists are now proposing two more vaccine options based on DNA that encodes human immunodeficienct virus proteins. Experience proves that traditional ways of... view more... (2004-05-17)
Nanoparticle Assembly Enters the Fast Lane
The speed of nanoparticle assembly can be accelerated with the assistance of the molecule that carries life's genetic instructions, DNA, a team of researchers at the U.S. Department of Energy's Brookhaven National Laboratory recently found. view more (2006-10-12)
Phoenix rising: Scientists resuscitate a 5 million-year-old retrovirus
A team of scientists has reconstructed the DNA sequence of a 5-million-year-old retrovirus and shown that it is able to produce infectious particles. view more (2006-10-31)
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