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Ebola DNA vaccine produces immune responses in all fully vaccinated volunteers in Phase 1 trial
Vical Incorporated (Nasdaq:VICL) announced today that an Ebola vaccine candidate administered using Vical's proprietary DNA delivery technology was safe and well tolerated, and produced both antibody and T-cell Ebola-specific responses in all healthy volunteers who received the full 3 doses of vaccine. view more (2006-02-22)
Links between DNA damage and breast cancer studied
Researchers from the Pacific Northwest Research Institute (PNRI) and the National Institute of Standards and Technology (NIST) have uncovered a pattern of DNA damage in connective tissues in the human breast that could shed light on the early stages of breast cancer and possibly serve as an early warning of a heightened risk of cancer. view more (2006-08-07)
Cancer is a stem cell issue
There is an urgent reason to study stem cells: stem cells are at the heart of some, if not all, cancers. view more (2007-02-20)
Probability Controls The Molecule Of Life
Thanks to biophysicists, statistics has reached the most intimate aspect of life - regulation of genes' activity. Investigation on probabilistic aspects of molecular biology has been supported by the Russian Foundation for Basic Research and the INTAS Foundation. Regulation of genes' activity is one of the most important biological problems which... view more... (2004-05-24)
Insignia -- A new way to identify viruses and bacteria
Now that the genome sequences of hundreds of bacteria and viruses are known, we can design tests that will rapidly detect the presence of these species based solely on their DNA. view more (2007-05-18)
NIAID DNA vaccine for H5N1 avian influenza enters human trial
The first human trial of a DNA vaccine designed to prevent H5N1 avian influenza infection began on December 21, 2006, when the vaccine was administered to the first volunteer at the National Institutes of Health (NIH) Clinical Center in Bethesda, MD. view more (2007-01-05)
Scientists identify specific enzymes that make meningitis hard to fight
Two enzymes in meningitis bacteria which prevent the body from successfully fighting off the disease, and make the infection extremely virulent, have been identified in new research published today. view more (2007-02-23)
Gene-bender proteins may sway to DNA
Among the many genes packed into each cell of our body, those that get turned on, or expressed, are the ones that make us who we are. Certain proteins do the job of regulating gene expression by clasping onto key spots of DNA - the nucleic acid that contains the genetic instructions. view more (2006-12-05)
HPV testing a cost-effective strategy for women with equivocal cervical screening results
A new study has found that using human papillomavirus (HPV) DNA testing to determine who should receive a cervical examination called colposcopy is a cost-effective management strategy for women with equivocal Pap test results known as ASCUS (atypical squamous cells of undetermined significance). view more (2006-01-18)
Researchers identify gene as protector of DNA, enemy of tumors
A single gene plays a pivotal role launching two DNA damage detection and repair pathways in the human genome, suggesting that it functions as a previously unidentified tumor suppressor gene. view more (2006-08-07)
DNA replication behavior in complex organisms may foreshadow leaps in genomic discoveries
For the first time, findings by scientists at the Genome Institute of Singapore (GIS) may be paving the way for more efficient analyses and tests related to the replication of cells, and ultimately, to the better understanding of human biology, such as in stem cell research. view more (2007-08-16)
Cancer related gene p53 not regulated as indicated by previous tissue culture research
The cellular cascade of molecular signals that instructs cells with fatally damaged DNA to self-destruct pivots on the p53 tumor suppressor gene. view more (2005-06-28)
New role for gene that counteracts formation of tumors
The researchers, connected to Ghent University, have discovered the function of an important mediator involved in suppressing the development of tumors. view more (2005-08-26)
Johns Hopkins researchers find link between cell's energy use and genome health
While studying how a cell keeps its genetic material intact, scientists at Johns Hopkins got busy alternately knocking out two catalysts vital to managing a yeast cell's energy. view more (2006-07-24)
Two More Potential HIV Vaccines
Despite long-term researchers' efforts, efficient human immunodeficienct virus (HIV) vaccine has not been created yet. However, researchers are not giving up their attempts. Russian biologists are now proposing two more vaccine options based on DNA that encodes human immunodeficienct virus proteins. Experience proves that traditional ways of... view more... (2004-05-17)
Neandertals, humans share key changes to 'language gene'
A new study published online on October 18th in Current Biology reveals that adaptive changes in a human gene involved in speech and language were shared by our closest extinct relatives, the Neandertals. view more (2007-10-19)
Brown Engineers Use DNA to Direct Nanowire Assembly and Growth
A research team led by Brown University engineers has harnessed the coding power of DNA to create zinc oxide nanowires on top of carbon nanotube tips. The feat, detailed in the journal Nanotechnology, marks the first time that DNA has been used to direct the assembly and growth of complex nanowires. view more (2006-07-17)
New 'litmus test' could aid discovery of anti-cancer drugs
Using the unusual color properties of gold at the nanoscale, scientists at Northwestern University have developed a "litmus test" for DNA and small molecule binding that eventually could be used by pharmaceutical companies to rapidly identify promising candidates for new anti-cancer drugs. view more (2006-03-29)
Computational model simulates AZT metabolism in mitochondria
Researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech have developed a computational model that allows scientists to better understand the metabolism and toxicity of the HIV/AIDS drug zidovudine (azidothymidine, AZT). view more (2006-07-25)
Scientists sequence DNA of woolly mammoth
Experts in ancient DNA from McMaster University (Canada) have teamed up with genome researchers from Penn State University (USA) for the investigation of permafrost bone samples from Siberia. view more (2005-12-20)
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