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Stress could damage DNA
A ground-breaking experiment has suggested that a certain type of stress could actually damage humans' DNA.   view more (2004-08-23)

Cash boost for research into leukaemia
Scientists from the University of Sussex in Brighton have been awarded £147,000 by the Leukaemia Research Fund (LRF) to look at abnormalities in DNA damage and repair that occur in some leukaemias and lymphomas. The research team ¾ led by Dr Penny Jeggo at the Genome Damage and Stability Centre ¾ will look at Seckel Syndrome, a rare... view more... (2002-09-11)

Clemson chemists discover new way antioxidants fight debilitating diseases
Cancer, cardiovascular diseases, Parkinson's and Alzheimer's are often linked to DNA damage that occurs when metal ions in the body such as iron and copper produce reactive oxygen compounds that damage human cells.   view more (2007-08-20)

U of Alberta study discovers how proteins help repair DNA
A person's DNA is often damaged by a number of different chemical contaminants, and if not repaired properly, it can lead to the development of cancer and other diseases.   view more (2009-06-16)

DNA repair mechanisms relocate in response to stress
Like doctors making house calls, some DNA repair enzymes can relocate to the part of the cell that needs their help, a collaborative team of scientists at Emory University School of Medicine has found.   view more (2009-03-27)

Hot Paper in the Biochemical Journal
DNA DAMAGE INSIGHT An exciting new paper from the Biochemical Journal regarding the phosphorylation state of LKB1 in response to ionising radiation can be viewed online as an Immediate Publication at www.BiochemJ.org (DOI: 10.1042/BJ20021284). Researchers at the University of Dundee, the University of Calgary and Tel Aviv University collaborated... view more... (2002-09-20)

New step in DNA damage response in neurons discovered
Researchers have identified a biochemical switch required for nerve cells to respond to DNA damage.   view more (2009-01-20)

UNC scientists discover cellular 'SOS' signal in response to UV skin damage
New research from the University of North Carolina at Chapel Hill School of Medicine has identified two proteins that may help protect against skin cancer.   view more (2007-03-19)

A potential approach to treatment of hepatitis B virus infection
Eukaryotic cells employ multiple strategies of checkpoint signaling and DNA repair mechanisms to monitor and repair damaged DNA.   view more (2008-09-10)

Damage to sperm DNA affects older men's chances of fathering children
Damage to DNA in sperm is significantly higher in older men than in those who are younger, according to research presented today (Tuesday 21 June 2005) at the 21st annual conference of the European Society of Human Reproduction and Embryology.   view more (2005-06-21)

Study links high levels of nitric oxide to infertility and sperm DNA damage
Iranian scientists have linked a chemical that plays an essential role in many bodily functions to sperm DNA damage and male infertility.   view more (2006-06-19)

Finding that 1-in-a-billion that could lead to disease
Errors in the genetic code can give rise to cancer and a host of other diseases, but finding these errors can be more difficult than looking for the proverbial needle in the haystack.   view more (2007-08-20)

UVA researchers explain cell response to skin-damaging UV rays
It's well known that overexposure to ultraviolet rays from the sun can cause major skin problems, ranging from skin cancer to sunburns and premature wrinkles. A tan, for example, is nature's own UV protection and an unhealthy sign that your skin is damaged.   view more (2007-10-02)

DNA differences may influence risk of Hodgkin disease
A new analysis has found that certain variations in genes that repair DNA can affect a person's risk of developing Hodgkin disease.   view more (2009-03-09)

Daily sex helps to reduce sperm DNA damage and improve fertility
Daily sex (or ejaculating daily) for seven days improves men's sperm quality by reducing the amount of DNA damage.   view more (2009-06-30)

A cancer gene causing tumours by a 'double-whammy' mechanism also reveals the key to a cure
Scientists at the Babraham Institute have discovered that a tiny change in a protein involved in cell survival is responsible for abnormal cell activity in the early stages of cancer. The protein, known as Bcl-xL, normally protects cells from dying; and when the DNA in cells becomes damaged, Bcl-xL is modified so that it no longer keeps the cells... view more... (2004-01-21)

Seemingly suicidal stunt is normal rite of passage for immune cells
Researchers have shown that self-induced breaks in the DNA of immune cells known as lymphocytes activate genes that cause the cells to travel from where they're made to where they help the body fight invaders.   view more (2008-10-21)

Precision biochemistry tracks DNA damage in fish
Like coal-mine canaries, fish DNA can serve as a measure of the biological impact of water and sediment pollution-or pollution clean-up.   view more (2006-05-15)

Surprising new insights into the repair strategies of DNA
A microscopic single-celled organism, adapted to survive in some of the harshest environments on earth, could help scientists gain a better understanding of how cancer cells behave.   view more (2009-07-16)

Chromatin remodeling complex connected to DNA damage control
When molecular disaster strikes, causing structural damage to DNA, players in two important pathways talk to each other to help contain the wreckage, scientists at The University of Texas M. D. Anderson Cancer Center report in the August edition of Cell.   view more (2007-08-10)
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