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How vitamin C stops the big 'C'
Nearly 30 years after Nobel laureate Linus Pauling famously and controversially suggested that vitamin C supplements can prevent cancer, a team of Johns Hopkins scientists have shown that in mice at least, vitamin C - and potentially other antioxidants - can indeed inhibit the growth of some tumors - just not in the manner suggested by years of... view more... (2007-09-11)
UCLA cancer researchers first to link intestinal inflammation with systemic chromosome damage
UCLA scientists have linked for the first time intestinal inflammation with systemic chromosome damage in mice, a finding that may lead to the early identification and treatment of human inflammatory disorders. view more (2009-06-01)
Linking DNA and histone methylation
In the May 15th issue of G&D, Dr. Michael Carey (UCLA's Jonsson Comprehensive Cancer Center) and colleagues lend new insight into the mechanism of epigenetic silencing of euchromatic genes. view more (2007-04-30)
Junk DNA may prove invaluable in quest for gene therapies
Scientists have identified how a protein enables sections of so-called junk DNA to be cut and pasted within genetic code - a finding which could speed development of gene therapies. view more (2009-09-22)
Gene-bender proteins may sway to DNA
Among the many genes packed into each cell of our body, those that get turned on, or expressed, are the ones that make us who we are. Certain proteins do the job of regulating gene expression by clasping onto key spots of DNA - the nucleic acid that contains the genetic instructions. view more (2006-12-05)
Ultraviolet B light exposure associated with increased risk of skin cancer
A decreased ability to repair chromosomal damage caused by exposure to ultraviolet B (UV-B) radiation in test tubes may be associated with an increased risk of the common skin cancers basal cell carcinoma and squamous cell carcinoma, but not of melanoma. view more (2005-12-21)
Stability of mRNA/DNA and DNA/DNA duplexes modulates mRNA transcription
The distribution of the four nucleotides along the DNA sequence encodes the genetic information in living systems. However, do nucleic acids possess other attributes that contribute to their biological functions? view more (2007-03-14)
FISH-ing for links between cancer and aging
Wielding a palette of chromosome paints, scientists at the Salk Institute for Biological Studies have taken a step closer to understanding the relationship between aging and cancer by visualizing chromosomes of cells from patients with a heritable premature aging disease known as Werner Syndrome. view more (2007-02-06)
Boston University scientists develop new application to characterize structure of DNA molecules
A team of researchers from Boston University has developed a new application to enable more precise measurement of the location of a fluorescent label in a DNA layer. view more (2006-03-01)
Study shows Chronix technology using serum DNA can identify early presence of disease
Chronix Biomedical today reported that a new study in a peer-reviewed journal further confirms the potential diagnostic and prognostic utility of using circulating fragments of DNA to detect early stage disease. view more (2009-06-23)
UIC researchers show how cancer-preventing foods work
Researchers at the University of Illinois at Chicago are unraveling the biochemical mechanism by which functional foods combat cancer. view more (2005-07-11)
Blood test to predict diabetes in children
The researchers found that four out of five patients with juvenile diabetes have the so-called islet antibodies directed against GAD and IA2 in their blood before the condition manifests itself and that these proteins occur exclusively in cases of juvenile diabetes. The test measures the concentration of the islet antibodies in the child's blood.... view more... (2000-01-18)
Scientists Discover Role of Enzyme in DNA Repair
Scientists from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Cancer Institute (NCI), and Integrative Bioinformatics Inc. have made an important discovery about the role of an enzyme called ataxia telangiectasia mutated protein (ATM) in the body's ability to repair damaged DNA. NIAMS and NCI are part... view more... (2007-06-28)
Seeing the damage helps prevent dangerous UV exposure
The best way to persuade people not to risk sun tan damage is to actually show them the current state of their skins, rather than simply describing it. This is the finding reported in a paper given by Dr Frederick Gibbons, of Iowa State University, USA, in a symposium on risk perception today, Tuesday 3 July, at the European Congress of... view more... (2001-06-25)
Centromeres cross over, a lot
Recombination at centromeres is higher than anywhere else on the chromosome, even though methyltransferases do their best to prevent it, say Jaco et al., as published in the June 16 issue of the Journal of Cell Biology. view more (2008-06-13)
Researchers test reliability of forensic DNA technology in fight against crime
Researchers from Barts and The London, Queen Mary`s School of Medicine and Dentistry are to team up with colleagues from universities in Germany, Spain and Denmark in a £1m European research collaboration to test DNA techniques used to solve crime. DNA is often used by forensic scientists to identify persons from physical evidence left... view more... (2002-07-26)
OHSU Cancer Institute researchers pinpoint how smoking causes cancer
Oregon Health & Science University Cancer Institute researchers have pinpointed the protein that can lead to genetic changes that cause lung cancer. view more (2008-05-14)
Genetic double-agents unmasked
Babraham Institute and Cancer Research UK scientists have discovered that certain enzymes with a key activity in the immune system may be important in stem-cell development, but may also work against us by contributing to the occurrence of cancer. view more (2004-10-26)
Mouse to man: The story of chromosomes
The complete sequencing of human chromosome 17 and mouse chromosome 11 offers unique insights into the evolution of the genome of higher mammals. view more (2006-04-20)
MRI is Better Than SPECT in Assessing Heart Damage in Patients with Hypertrophic Cardiomyopathy
Contrast-enhanced MRI is better than SPECT in detecting heart damage in patients with hypertrophic cardiomyopathy, a disease that can lead to sudden death in young patients. view more (2005-08-08)
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