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A potential approach to treatment of hepatitis B virus infection
Eukaryotic cells employ multiple strategies of checkpoint signaling and DNA repair mechanisms to monitor and repair damaged DNA. view more (2008-09-10)
New step in DNA damage response in neurons discovered
Researchers have identified a biochemical switch required for nerve cells to respond to DNA damage. view more (2009-01-20)
Assessment model gauges lung cancer risk based on medical history and genetics
Physicians have little to help them predict development of lung cancer in their patients-even a history of heavy smoking doesn't really help, since only a small fraction of lifetime smokers develops the cancer. view more (2006-04-05)
Researchers probe a DNA repair enzyme
U. of I. researchers have taken the first steps toward understanding how an enzyme repairs DNA. Enzymes called helicases play a key role in human health, according to Maria Spies, a University of Illinois biochemistry professor. view more (2008-02-19)
University of Minnesota researchers take new look at cellular suicide
Like a bodyguard turned traitor, a protein whose regular job is to help repair severed DNA molecules will, in some cases, join forces with another protein to do the opposite and chop the DNA to bits. view more (2006-07-07)
Seemingly suicidal stunt is normal rite of passage for immune cells
Researchers have shown that self-induced breaks in the DNA of immune cells known as lymphocytes activate genes that cause the cells to travel from where they're made to where they help the body fight invaders. view more (2008-10-21)
Cell survival depends on chromosome integrity
As part of a large National Institutes of Health-funded Technology Centers for Networks and Pathways project, Johns Hopkins researchers have discovered protein machinery important for cells to keep chromosomes intact. view more (2006-07-10)
Discovery may result in new test to determine predisposition to cancer
Researchers at UCLA's Jonsson Comprehensive Cancer Center have developed an assay that may be used to help identify new genes that can predict a predisposition to cancer. view more (2009-03-25)
New information about DNA repair mechanism could lead to better cancer drugs
Researchers at Washington University School of Medicine in St. Louis have shed new light on a process that fixes breaks in the genetic material of the body's cells. view more (2009-07-17)
Lithium may help radiation target cancer, spare healthy tissue
Vanderbilt-Ingram Cancer Center investigators have uncovered a mechanism that helps explain how lithium, a drug widely used to treat bipolar mood disorder, also protects the brain from damage that occurs during radiation treatments. view more (2009-05-05)
Sunburn alert: UVB does more damage to DNA than UVA
As bombs burst in air this July 4, chances are that sunburn will be the red glare that most folks see - and feel. But unfortunately, even when there is no burn, the effects of the sun's ultraviolet (UV) rays can have deadly consequences. view more (2008-07-01)
Scientists reveal DNA-enzyme interaction with first ever real time footage
For the first time scientists have been able to film, in real-time, the nanoscale interaction of an enzyme and a DNA strand from an attacking virus. view more (2007-09-18)
Nanoscale microscope sheds first light on gene repair
Proteins called H2AX act as "first aid" to DNA, among other roles. For the first time, scientists using the world's most powerful light microscope (the only one of its kind in the Americas) have seen how H2AX is distributed in the cell nucleus: in clusters, directing the first aid/repair after DNA injuries to the region where it is... view more... (2006-11-14)
Study supports DNA repair-blocker research in cancer therapy
Scientists at Dana-Farber Cancer Institute have uncovered the mechanism behind a promising new approach to cancer treatment: damaging cancer cells' DNA with potent drugs while simultaneously preventing the cells from repairing themselves. view more (2009-08-18)
Mayo Clinic research collaboration discovers why some DNA repair fails
Mayo Clinic researchers have discovered the inner workings of a defective DNA repair process and are first to explain why certain mutations are not corrected in cells. view more (2005-10-04)
Press Briefing - Leading scientists explore the next 50 years of DNA related research
Leading international scientists in the field of molecular biology will be attending a scientific discussion meeting entitled 'Replicating and reshaping DNA: a celebration of the jubilee of the double helix' at the Royal Society on 23rd and 24th April 2003. The meeting will look at the cutting edge of today's science of DNA and how the intricate... view more... (2003-04-16)
Researchers uncover protection mechanism of radiation-resistant bacterium
Recent discoveries by researchers at the Uniformed Services University of the Health Sciences (USU) could lead to new avenues of exploration for radioprotection in diverse settings. Michael J. Daly, Ph.D., an associate professor in USU's Department of Pathology, and his colleagues have uncovered evidence pointing to the mechanism through which the... view more... (2007-03-21)
Mayo-led study finds smoking related to subset of colorectal cancers
Smoking puts older women at significant risk for loss of DNA repair proteins that are critical for defending against development of some colorectal cancers, according to research from a team led by Mayo Clinic scientists. view more (2008-04-14)
Study links faulty DNA repair to Huntington's disease onset
Huntington's disease, an inherited neurodegenerative disorder that affects roughly 30,000 Americans, is incurable and fatal. view more (2007-04-23)
DNA’s oscillating double helix hinders electrical conduction
DNA has an oscillating double-helix structure. This oscillating means that the DNA molecules conduct electricity much less well than was previously thought. Ultrafast cameras were one of the devices the researchers from Amsterdam used to demonstrate this. It turns out the DNA does not have a rigid regular structure as stated in textbooks. In... view more... (2002-09-11)
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