DNA repair Current Events | DNA repair News | 4
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Scientists track impact of DNA damage in the developing brain Switching off a key DNA repair system in the developing nervous system is linked to smaller brain size as well as problems in brain structures vital to movement, memory and emotion. view more (2009-07-28)
Raising the alarm when DNA goes bad Our genome is constantly under attack from things like UV light and toxins, which can damage or even break DNA strands and ultimately lead to cancer and other diseases. view more (2009-08-14)
DNA repair in mammal embryos is a matter of timing Investigators at St. Jude Children's Research Hospital have discovered that the cells of the developing nervous system of the mammalian embryo have an exquisite sense of timing when it comes to fixing broken chromosomes: the cells use one type of repair mechanism during the first half of development and another during the second half. view more (2006-06-20)
Cancer stem cells linked to radiation resistance Certain types of brain cancer cells, called cancer stem cells, help brain tumors to buffer themselves against radiation treatment by activating a "repair switch" that enables them to continue to grow unchecked. view more (2006-10-19)
UVA researchers explain cell response to skin-damaging UV rays It's well known that overexposure to ultraviolet rays from the sun can cause major skin problems, ranging from skin cancer to sunburns and premature wrinkles. A tan, for example, is nature's own UV protection and an unhealthy sign that your skin is damaged. view more (2007-10-02)
DNA: Bacteria's survival ration The ubiquitous bacteria E. coli rank among nature's most successful species for lots of reasons, to which biologists at the University of Southern California have added another: in a pinch, E. coli can feast on the DNA of their dead competitors. view more (2006-05-30)
Scientists Discover Role of Enzyme in DNA Repair Scientists from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Cancer Institute (NCI), and Integrative Bioinformatics Inc. have made an important discovery about the role of an enzyme called ataxia telangiectasia mutated protein (ATM) in the body's ability to repair damaged DNA. NIAMS and NCI are part... view more... (2007-06-28)
Researchers reveal structure of protein that repairs damage to cancer cells A team of University of Chicago scientists has shown how two proteins locate and repair damaged genetic material inside cells. view more (2008-04-24)
Cigarette smoke blocks cell repair mechanism, University of Florida study shows Cigarette smoke can turn normal breast cells cancerous by blocking their ability to repair themselves, eventually triggering tumor development, University of Florida scientists report. view more (2006-08-23)
Timing of radiation treatments for colon cancer may need adjusting, Jefferson researchers say Scientists have unexpectedly discovered that mice with the gene defect that causes colon cancer in humans can differ from normal mice in how they respond to radiation treatments. view more (2006-04-10)
UNC study supports role of circadian clock in response to chemotherapy For years, research has hinted that the time of day that cancer patients receive chemotherapy can impact their chances of survival. But the lack of a clear scientific explanation for this finding has kept clinicians from considering timing as a factor in treatment. view more (2009-01-13)
Human RecQ helicases, homologous recombination and genomic instability Two independent papers in the December 1st issue of G&D detail how human RecQ helicases regulate homologous recombination and protect genome stability. view more (2007-11-15)
Baumann Lab Defines Proteins that Distinguish Chromosome Ends from DNA Double-Strand Breaks Peter Baumann, Ph.D., Assistant Investigator, and Nancy Bae, Ph.D., Postdoctoral Research Associate in the Baumann Lab, have published a paper offering insight into the way cells protect chromosome ends from misguided repair. view more (2007-05-11)
Researchers find the mechanism by which cells resist chemotherapy In his paper, to be published in The EMBO Jorunal, Dr Surrallés describes how proteins of the Fanconi/BRCA pathway recognise the presence of genetic mutations in order to repair them. view more (2007-03-05)
New mechanism discovered for DNA recombination and repair A biochemistry research team led by Dr. Andrew H.-J. Wang and Dr. Ting-Fang Wang at the Institute of Biological Chemistry, Academia Sinica(IBCAS), has discovered that the RecA family recombinases function as a new type of rotary motor proteins to repair DNA damages. view more (2007-09-12)
Scientists decipher missing piece of first-responder DNA repair machine Scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory and the Scripps Research Institute have uncovered the role played by the least-understood part of a first-responder molecule that rushes in to bind and repair breaks in DNA strands, a process that helps people avoid cancer. view more (2009-10-02)
Analysis reveals extent of DNA repair army Cells have the remarkable ability to keep track of their genetic contents and -- when things go wrong " to step in and repair the damage before cancer or another life-threatening condition develops. view more (2007-05-25)
NICE guidance must be applied more effectively Guidance from the National Institute for Clinical Excellence (NICE) must be implemented more effectively to improve NHS practice, suggest researchers in this week's BMJ. They describe patterns of surgical repair for hernias before and after NICE guidance that recommended the open mesh technique over laparoscopic repair. They also assessed the... view more... (2003-03-12)
Removing DNA repair gene causes metabolic syndrome Removing a gene involved in repairing damaged DNA causes mice to develop the metabolic syndrome, researchers at Oregon Health & Science University have discovered. view more (2006-02-09)
Ultraviolet B light exposure associated with increased risk of skin cancer A decreased ability to repair chromosomal damage caused by exposure to ultraviolet B (UV-B) radiation in test tubes may be associated with an increased risk of the common skin cancers basal cell carcinoma and squamous cell carcinoma, but not of melanoma. view more (2005-12-21)
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