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Potential therapy for congenital muscular dystrophy
Current research suggests laminin, a protein that helps cells stick together, may lead to enhanced muscle repair in muscular dystrophy. view more (2008-12-30)
Gene regulation in humans is closer than expected to simple organisms
Gene networks are some of the most basic features of a living organism. An external or internal stimulus activates some genes, which in turn control others genes whose activity turns on or off various biological processes (such as the cell cycle, energy production, DNA repair, cellular suicide etc). view more (2007-08-30)
Fistula-related morbidity decreased by prompt treatment in Sierra Leone
Extent of fibrosis is the most profound factor in predicting surgical outcomes of genitourinary fistula repair, suggesting that prompt treatment could significantly improve survival. view more (2009-04-27)
EMSY: a new gene for breast/ovarian cancer
A new human breast and ovarian cancer gene has just been described by investigators in the last issue of the journal Cell. The gene, called EMSY, also characterises a subset of breast cancer with poorer survival, which makes it a potentially important diagnostic tool. view more (2003-12-10)
Can brain-injured, partially-blind stroke patients regain some of their lost vision?
Is it possible to offer hope for stroke patients who've lose part of their vision? A study published by SAGE in the journal Neurorehabilitation & Neural Repair explores that question. view more (2007-09-05)
MRI better than MDCT in detecting endoleaks, study says
Contrast-enhanced MR imaging is significantly superior to 16 slice multidetector CT in the detection of endoleaks after endovascular repair of abdominal aortic aneurisms (EVAR), according to a recent study conducted by researchers at Ospedale San Giovanni in Bellinzona, Switzerland. view more (2008-04-14)
Electronic structure of DNA revealed for 1st time by Hebrew University and collaborating researchers
Utilizing a technique that combines low temperature measurements and theoretical calculations, Hebrew University of Jerusalem scientists and others have revealed for the first time the electronic structure of single DNA molecules. view more (2008-02-29)
Researchers identify gene as protector of DNA, enemy of tumors
A single gene plays a pivotal role launching two DNA damage detection and repair pathways in the human genome, suggesting that it functions as a previously unidentified tumor suppressor gene. view more (2006-08-07)
Evolution of human genome's 'guardian' gives people unique protections from DNA damage
Human evolution has created enhancements in key genes connected to the p53 regulatory network - the so-called guardian of the genome - by creating additional safeguards in human genes to boost the network's ability to guard against DNA damage that could cause cancer or a variety of genetic diseases. view more (2008-01-17)
The world's oldest bacteria
A research team has for the first time ever discovered DNA from living bacteria that are more than half a million years old. Never before has traces of still living organisms that old been found. view more (2007-08-28)
Precision biochemistry tracks DNA damage in fish
Like coal-mine canaries, fish DNA can serve as a measure of the biological impact of water and sediment pollution-or pollution clean-up. view more (2006-05-15)
Study identifies 5 genetic themes key to keeping stem cells in a primitive, flexible state
For more than 25 years, stem cells have been defined based on what they can become: more of themselves, as well as multiple different specialized cell types. view more (2007-06-20)
Hot Paper in the Biochemical Journal
DNA DAMAGE INSIGHT An exciting new paper from the Biochemical Journal regarding the phosphorylation state of LKB1 in response to ionising radiation can be viewed online as an Immediate Publication at www.BiochemJ.org (DOI: 10.1042/BJ20021284). Researchers at the University of Dundee, the University of Calgary and Tel Aviv University collaborated... view more... (2002-09-20)
Less-invasive technique has improved outcomes of aortic aneurysm repair
A shift toward a less-invasive endovascular procedure as an alternative to conventional surgery has reduced the risk of death for patients undergoing repair of dangerous abdominal aortic aneurysms (AAAs), reports a study in the March Journal of Vascular Surgery. view more (2006-03-08)
Damage to sperm DNA affects older men's chances of fathering children
Damage to DNA in sperm is significantly higher in older men than in those who are younger, according to research presented today (Tuesday 21 June 2005) at the 21st annual conference of the European Society of Human Reproduction and Embryology. view more (2005-06-21)
Cornell researchers identify a weak link in cancer cell armor
The seeming invincibility of cancerous tumors may be crumbling, thanks to a promising new gene therapy that eliminates the ability of certain cells to repair themselves. view more (2009-11-13)
Diabetes linked to male infertility; excess sugars in the body have direct effect on sperm quality
Diabetes in men has a direct effect on fertility, a scientist told the 24th annual conference of the European Society of Human Reproduction and Embryology today. view more (2008-07-09)
Photonic crystal biosensors detect protein-DNA interactions
Scientists at the University of Illinois have developed a new class of disposable, microplate-based optical biosensors capable of detecting protein-DNA interactions. Based on the properties of photonic crystals, the biosensors are suitable for the rapid identification of inhibitors of protein-nucleic acid and protein-protein interactions. view more (2008-09-24)
DNA editing tool flips its target
Imagine having to copy an entire book by hand without missing a comma. Our cells face a similar task every time they divide. They must duplicate both their DNA and a subtle pattern of punctuation-like modifications on the DNA known as methylation. view more (2008-09-04)
Change in gene may be underlying molecular defect in some colorectal cancers, study suggests
Inactivation of a DNA repair gene may be an early step in the development of sporadic colorectal tumors, and detection of the molecular basis for this inactivation may ultimately be useful in risk assessment for colorectal cancer. view more (2005-09-21)
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