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DNA repair Current Events | DNA repair News | 9

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Weizmann Institute scientists discover a molecular security mechanism for keeping mutations in check
Everyone knows mutations - genetic mistakes in DNA, the material of heredity - are bad: The more mutations in the cell's DNA, the higher the risk of cancer developing.   view more (2006-05-05)

Continuous Stiching Method Reduces Pain For Women With Perineal Damage After Childbirth
Authors of a study in this week's issue of THE LANCET suggest that a simple, continuous stitching technique to repair tears to the perineum after vaginal delivery can prevent one woman in six from having pain ten days after childbirth. The study also highlights how the use of more rapidly absorbed suture material can avoid the need for the removal... view more... (2002-06-26)

Brain cells help neighboring nerves regenerate
Researchers have uncovered a completely unexpected way that the brain repairs nerve damage, wherein cells known as astrocytes deliver a protective protein to nearby neurons.   view more (2008-05-28)

Trial shows which brain cancer patients benefit from temozolomide
Genetic predictive test clears way for targeted drug treatment   view more (2004-09-26)

New gene associated with Fanconi anemia 'explains' hallmark chromosomal instability
Surprising findings from just five patients has led to the first proof of how the rare disorder Fanconi anemia causes chromosomal instability.   view more (2005-08-22)

Evalve MitraClip: Clinical trial of nonsurgical repair for severe mitral valve regurgitation
The Cedars-Sinai Heart Institute is the lead enroller in the world for the Everest II Clinical Trial - a study comparing non-surgical repair for severe mitral valve regurgitation with conventional surgery.   view more (2008-06-19)

Scientists discover a genetic code for organizing DNA within the nucleus
DNA - the long, thin molecule that carries our hereditary material - is compressed around protein scaffolding in the cell nucleus into tiny spheres called nucleosomes.   view more (2006-07-20)

Antitumor agent under the microscope
Mechanical stabilization of DNA keeps tumor cells in check Cisplatin is one of the most widely employed cancer medications. As with many other chemotherapy agents, the mechanism by which it works has not been fully researched. Now, thanks to Munich physicists Hermann E. Gaub, Rupert Krautbauer, and Hauke Clausen-Schaumann, an important step toward... view more... (2000-10-30)

Gladstone scientists identify key factors in heart cell creation
Scientists at the Gladstone Institute of Cardiovascular Disease have identified for the first time key genetic factors that drive the process of generating new heart cells.   view more (2009-04-27)

'Smart scaffolds' may help heal broken hearts
Imagine new treatments for heart disease or muscle loss that direct the body to repair damaged tissue rather than helping it cope with a weakened condition.   view more (2009-01-13)

Newly found DNA catalysts cleave DNA with water molecule
Better tools for manipulating DNA in the laboratory may soon be possible with newly discovered deoxyribozymes (catalytic DNA) capable of cleaving single-stranded DNA, researchers at the University of Illinois say.   view more (2009-08-17)

Baylor researchers unravel mystery of DNA conformation
An iconic photograph of Nobel laureates Drs. Francis Crick and James Watson show the pair discussing with a rigid model of the famous double helix.   view more (2009-07-14)

Enzyme necessary for DNA synthesis can also erase DNA
In this week's edition of Proceedings of the National Academy of Sciences, PNAS, Uppsala University scientists describe a new mechanism behind an important process that causes a rapid reduction of DNA in the chromosomes of bacteria.   view more (2009-06-09)

DNA constraints control structure of attached macromolecules
A new method for manipulating macromolecules has been developed by researchers at the University of Illinois at Urbana-Champaign. The technique uses double-stranded DNA to direct the behavior of other molecules.   view more (2005-06-29)

Have The Police Hijacked Our DNA? (p 927)
Creating a DNA database of all UK men to assist in criminal investigations may sound extreme; however this week's editorial proposes that there has been no more rational option to date in an attempt to use DNA profiling to assist in the identification of violent offenders in the UK, 80% of whom are men. The over-reliance by police and governments... view more... (2003-09-17)

Layered approach may yield stronger, more successful bone implants
Researchers from the American Dental Association Foundation (ADAF) and the National Institute of Standards and Technology (NIST) have developed a new method for layering two kinds of biomaterials into one strong, yet porous unit that may lead to improved reconstruction or repair of bones.   view more (2007-08-20)

Liposuctioned fat stem cells to repair bodies
Expanding waistlines, unsightly bulges: people will gladly remove excess body fat to improve their looks. But unwanted fat also contains stem cells with the potential to repair defects and heal injuries in the body.   view more (2007-02-23)

Standard chemo works better against metastatic BRCA1/2 breast cancer than against sporadic tumors
The first study to investigate the effects of chemotherapy on metastatic breast cancer in women with the BRCA1 or BRCA2 gene mutation has shown that standard chemotherapy works better in these patients than in women without the BRCA1/2 mutation.   view more (2008-04-17)

Skin care: new research into scar-free healing
New research from the University of Bristol shows that by suppressing one of the genes that normally switches on in wound cells, wounds can heal faster and reduce scarring. This has major implications not just for wound victims but also for people who suffer organ tissue damage through illness or abdominal surgery.   view more (2008-01-21)

Why missing out on a good night's sleep could give you ulcers
Missing out on a good night's sleep through long haul travel, shift work, or partying could increase the risk of ulcers. Research in Gut shows that levels of a chemical, produced by the stomach and small intestine to repair tissue damage, are highest at night, and are suppressed after a meal. Twelve healthy, 20 to 24 year old non-smokers were... view more... (2001-04-10)
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