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Researchers find brain cell transplants help repair neural damage
A Swiss research team has found that using an animal's own brain cells (autologous transplant) to replace degenerated neurons in select brain areas of donor primates with simulated but asymptomatic Parkinson's disease and previously in a motor cortex lesion model, provides a degree of brain protection and may be useful in repairing brain lesions... view more... (2009-10-29)
Adult brain cells rediscover their inner child
You may not be able to relive your youth, but part of your brain can. Johns Hopkins researchers have found that newly made nerves in an adult brain's learning center experience a one-month period when they are just as active as the nerves in a developing child. view more (2007-05-24)
Gains in the fight against acid aspiration lung injury
Doctors are gaining new leverage in the fight against lung injury caused by acid reflux. The paper by Bonnans et al., "Lipoxin A4 regulates bronchial epithelial cell responses to acid injury," appears in the April issue of The American Journal of Pathology and is accompanied by a commentary. view more (2006-05-03)
CELL TRANSPLANTATION COULD RESTORE CARDIAC FUNCTION AFTER HEART ATTACK (p 491)
Issue 8 February 2003 Embargoed 0001 h (London time) 7 February 2003 French authors of a research letter in this week's issue of THE LANCET describe the preliminary success of transplanting muscle stem-cells from the thigh to the heart to restore damaged cardiac tissue after heart attack. The procedure was done in a 72-year-old man and resulted... view more... (2003-02-05)
Study details regulation of vital tumor suppressor gene p53
So vital is the p53 tumor suppressor gene in controlling cancer that its dysfunction is linked to more than half of human cancers. view more (2007-09-06)
U-M team identifies gene that regulates blood-forming fetal stem cells
In the rancorous public debate over federal research funding, stem cells are generally assigned to one of two categories: embryonic or adult. view more (2007-07-27)
Cell division studies hint at future cancer therapy
When a cell's assets get divided between daughter cells, Dr. Quansheng Du wants to make sure both offspring do well. view more (2008-01-23)
Fibroblasts
Where should stem cells be taken for transplantation in case of deep burns - from embryos or from the marrow? Russian transplantologists have determined that the skin restores quicker when the cell from mesenchyme of the marrow are used. Within a month, the rat's burn wound area would decrease by 10 times, if its surface is covered by the... view more... (2003-11-06)
Severed nerves can be made to grow again
IT IS being hailed as one of the most significant advances in nerve regeneration in a decade. After severing an optic nerve in rats, neurologists have found a way to reconnect it to the brain so that it once again transmits normal electrical signals. The achievement is a first in mammals, and may... view more... (2001-12-05)
New pathway provides more clues about BRCA1 role in breast cancer
A breast cancer gene's newly discovered role in repairing damaged DNA may help explain why women who inherit a mutated copy of the gene are at increased risk for developing both breast and ovarian cancer. view more (2008-01-16)
Injection of 'skin filler' material appears to stimulate collagen production
Injections with "dermal fillers" containing hyaluronic acid appear to stimulate production of collagen, a primary protein in the skin, and may partially restore the structure of sun-damaged skin, according to an article in the February issue of Archives of Dermatology, one of the JAMA/Archives journals. view more (2007-02-20)
Matrix fragments trigger fatal excitement
Shredded extracellular matrix (ECM) is toxic to neurons. Chen et al. reveal a new mechanism for how ECM demolition causes brain damage. The study will appear in the December 29, 2008 issue of The Journal of Cell Biology (www.jcb.org). view more (2008-12-30)
Stanford researchers find culprit in aging muscles that heal poorly
Communication is critical. Garbled in, garbled out, so to (mis-)speak. Workers who get incomplete instructions produce an incomplete product, and that's exactly what happens with the stem cells in our aging muscles. view more (2007-08-10)
Studies Suggest New Targets for Tuberculosis Treatments
With the hope of designing more effective treatments for tuberculosis (TB), scientists from the U.S. Department of Energy's Brookhaven National Laboratory and collaborating institutions have published the first detailed reports on the biochemistry and structure of a protein-cleaving complex that is essential to the TB bacterium's survival. view more (2006-03-07)
A twist of fate -- Reprogrammed fibroblasts resemble embryonic stem cells
Stem cell biology takes another exciting leap forward as scientists report that normal tissue cells can be reprogrammed to exhibit many of the properties that are characteristic of embryonic stem cells, including the ability to give rise to multiple cell types and contribute to the germline. view more (2007-06-07)
Scientists ask whether microscaffolding can help stem cells rebuild brain after stroke damage
Inserting tiny scaffolding into the brain could dramatically reduce damage caused by strokes the UK National Stem Cell Network Annual Science Meeting will hear today (10 April). view more (2008-04-10)
Protein in human hair shows promise for regenerating nerves
A protein found in human hair shows promise for promoting the regeneration of nerve tissue and could lead to a new treatment option when nerves are cut or crushed from trauma. view more (2008-01-11)
Overexcited neurons not good for cell health
Neurotransmitters have consequences. They initiate events that are critical to a healthy life, giving us the ability to move, to talk, to breathe, to think. But that's if the neurotransmitters are getting it right and sending proper signals downstream to muscle cells, neurons or other cells. view more (2007-12-18)
MRI detects early heart damage in patients with sarcoidosis
To detect heart damage early in patients with the immune system disorder sarcoidosis, who are at elevated risk of dieing from heart problems, magnetic resonance imaging is twice as sensitive as conventional methods. view more (2006-11-13)
3 proteins may play important role in nerve-cell repair
Some mature brain cells can grow new extensions when the amount of three particular proteins on their surface increases, a new study shows. view more (2007-04-12)
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