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SSRI antidepressants do not pose major birth defect risk
Researchers from Boston University's Slone Epidemiology Center have found that certain selective serotonin reuptake inhibitors antidepressants do not appear to increase the risk for most kinds of birth defects.   view more (2007-06-28)

Mother's vitamin D status during pregnancy will affect her baby's dental health
Low maternal vitamin D levels during pregnancy may affect primary tooth calcification, leading to enamel defects, which are a risk factor for early-childhood tooth decay.   view more (2008-07-07)

European folic acid policies are not effective enough
The prevalence of neural tube defects in Europe has not declined substantially in the past decade, despite national policies of folic acid supplementation in half the countries, finds a study in this week's BMJ.   view more (2005-03-09)

Genomic imprinting in disruptive spermatogenesis (p 1700)
Low sperm counts could be associated with genomic imprinting disease and could carry a raised risk of transmitting imprinting defects following assisted reproductive technologies, claim researchers in this week's issue of THE LANCET. Genomic imprinting is a gene regulatory mechanism based on... view more (2004-05-19)

Epilepsy drug causes eye problems in over 40 per cent of cases
Vigabatrin, a drug used to treat epilepsy, causes eye problems in over 40 per cent of those prescribed it, shows a study in the Journal of Neurology Neurosurgery and Psychiatry. Vigabatrin was licensed in the UK in 1989 and was the first anti-epileptic drug to come on to the marked since the 1970s.... view more (2002-08-20)

Food Supplementation With Folic Acid Could Substantially Reduce Neural-Tube Defects (p 2047)
A public-health initiative to enrich cereal grain foods in Canada with folic acid has halved the prevalence of neural-tube defects among both unborn and newborn children, report authors of a research letter in this week's issue of THE LANCET. Folic acid tablet supplementation around the time of... view more (2002-12-18)

Analysis of millions of US births shows association between birth defects and preterm birth
Babies born preterm were more than twice as likely to have major birth defects as full-term infants, according to a new analysis of nearly 7 million U.S. live births published online this week in the Springer journal Maternal and Child Health Journal.   view more (2008-05-21)

Is tap water safe for expectant mothers?
Drinking water disinfected by chlorine while pregnant may increase the risk of having children with heart problems, cleft palate or major brain defects, according to a study published today in BioMed Central's open access journal Environmental Health.   view more (2008-06-03)

Surgery to improve academic ability in children with congenital heart disease may not work
Surgery to correct congenital heart disease in children may not result in the hoped for improvements in intellectual and academic ability, suggests research in Heart. It is generally believed that congenital heart disease may impair intellectual and academic performance either because of the... view more (2001-05-17)

National statistics for 18 major birth defects released
Cleft lip is a treatable birth defect, but for the families of the estimated 6,800 U.S. infants born with one, it's a heartbreaking experience - not only because of the associated health problems, but because friends and family may ignore the condition or because of social stigma associated with... view more (2006-01-06)

Stress management: X-rays reveal Si thin-film defects
Pile-ups, bad on the freeway, also are a hazard for the makers of high-performance strained-silicon (Si) semiconductor devices.   view more (2006-07-10)

NO ASSOCIATION BETWEEN AGEING GAMETES AND BIRTH DEFECTS
Authors of a research letter in this week's issue of THE LANCET conclude that there is no evidence to support the belief that sexual intercourse too soon or two long after ovulation is associated with an increased risk of birth defects and Down's syndrome. For many years, the ageing of gametes as a... view more (2002-05-08)

Family history is a poor predictor of venous clotting
Family history of venous thromboembolism (blood clotting) is an unsatisfactory predictor for identifying common thrombophilic defects in women without thrombosis before taking oral contraceptives, finds a study in this week's BMJ. A total of 324 women (mean age 34 years) with no personal history of... view more (2001-04-24)

Fortifying food with folic acid benefits babies
Adding folic acid to food can dramatically reduce the incidence of spina bifida and other birth defects. A study, published today in BMC Pregnancy and Childbirth, shows that the proportion of babies born with neural tube defects in the province of Newfoundland and Labrador dropped by 78% after the... view more (2004-09-23)

Pregnant Women with Epilepsy Face Dilemma: Continue Treatment and Risk Birth Defects?
An article in the journal Epilepsia reviewed recent data on the risks associated with continuation of medical treatment of women with epilepsy during their pregnancies. While the general consensus is that use of antiepileptic drugs is associated with increased risk for birth defects, physicians... view more (2005-04-22)

Multivitamins with 0.4 - 0.8 mg of folic acid are best in birth defect prevention
Periconceptional use of folic acid supplements is effective for the primary prevention of neural-tube defects and is recommended by reproductive health researchers. Recent research in this area, however, centres on two main debated questions. The first one is whether the use of folic acid alone or... view more (2004-05-27)

Norwegian torpedo boat service associated with increased risk of birth defects
Military service aboard a Norwegian missile torpedo boat was associated with a signficantly increased risk of having children with birth defects or who were stillborn, reveals research in Occupational and Environmental Medicine.   view more (2006-01-17)

New insights into neural tube defects
Environmental and genetic factors lead to neural tube defects in 1 in every 1,000 births and cause 1 in 20 of every spontaneous abortion. One cause of these defects is the failure of cells within the neural tube to migrate to the middle of the developing neural tube.   view more (2006-01-12)

New data reveal pregnancies exposed to accutane despite risk management program
Despite a mandatory program designed to prevent pregnant women from being exposed to the anti-acne medication Accutane and similar medications containing isotretinoin (a known teratogen or birth defect-causing agent), 122 pregnancies were exposed during the first year of the program, known as... view more (2007-08-01)

Only one-third of women take vitamin to help prevent serious birth defects, survey finds
Only one-third of childbearing age women are taking a multivitamin containing the B vitamin folic acid daily to prevent serious birth defects of the brain and spine in their future babies, according to a decade of March of Dimes surveys.   view more (2005-09-30)

Kids with autism may have gene that causes muscle weakness
Some kids with autism may have a genetic defect that affects the muscles, according to research that will be presented at the American Academy of Neurology 60th Anniversary Annual Meeting in Chicago, April 12-19, 2008.   view more (2008-04-14)

Fertility drugs given 'all-clear' in new study
Concerns about the use of letrozole, an easy-to-use and inexpensive drug for the treatment of infertility, appear to be unfounded.   view more (2006-04-24)

Candidate genes found which may play a role in cancer progressing from non-invasive to invasive
Scientists in America have made the first steps in identifying a group of genes which may be involved in the progression of breast cancer from non-invasive to invasive, the 3rd European Breast Cancer Conference in Barcelona heard today (Thursday 21 March).   view more (2002-03-19)

UC Santa Barbara researchers light up 'dark' spins in diamond
Researchers at UC Santa Barbara have potentially opened up a new avenue toward room temperature quantum information processing. By demonstrating the ability to image and control single isolated electron spins in diamond, they unexpectedly discovered a new channel for transferring information to... view more (2005-10-27)

Researchers provide study of early heart development and underlying cause of congenital heart defects
Congenital heart defects involve the malformation in one or more structures of the heart or blood vessels while the fetus is developing in the uterus.   view more (2005-12-21)

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