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Defects Current Events | Defects News | 11
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Penn Researchers Identify First Sex Chromosome Gene Involved in Meiosis and Male Infertility A team of scientists led by University of Pennsylvania veterinary researchers have identified a gene, TEX11, located on the X chromosome, which when disrupted in mice renders the males sterile and reduces female fecundity. This is the first study of the genetic causes of infertility that links a... view more (2008-03-17)
Link between assisted reproduction techniques and genetic disruption Evidence that assisted reproduction techniques may carry a risk of genetic 'imprinting disorders' in the resulting babies, emerges in a study published in the Journal of Medical Genetics. To assess the likely risk of genetic disruption, geneticists from the University of Birmingham and the West... view more (2003-01-14)
Lower IQ found in children of women who took epilepsy drug Children of women who took the epilepsy drug valproate during pregnancy appear to be at a greater risk for lower IQ. view more (2007-05-04)
Early cardiac screening necessary for muscular dystrophy patients Early diagnosis and treatment of heart disease may lead to longer life in Duchenne and Becker muscular dystrophy patients. view more (2005-10-31)
June Issue Lasform - building aircraft parts from powder A new process for producing high-tech titanium components for the aerospace industry, using laser forming technology and powdered titanium, could help to reduce production costs for prototype parts. p.328 view more (1999-06-01)
Scientists at Low Temperature Laboratory planning to model a black hole Academy Professor Matti Krusius and Antti Finne, M.Sc. (Eng.), were invited to a recent science breakfast, hosted by the Academy of Finland, to talk about their ongoing work to produce a first-ever laboratory simulation of a black hole. A black hole is created as a result of the most extreme... view more (2003-04-16)
Study shows that genetic quality of sperm deteriorates as men age New research indicates that the genetic quality of sperm worsens as men get older, increasing a man's risk of being infertile, fathering unsuccessful pregnancies and passing along dwarfism and possibly other genetic diseases to his children. view more (2006-06-06)
Neurons find their place in the developing nervous system with the help of a sticky molecule The brain, that exquisite network of billions of communicating cells, starts to take form with the genesis of nerve cells. Most newborn nerve cells, also called neurons, must travel from their birthplace to the position they will occupy in the adult brain. view more (2006-04-26)
Researchers figure out how hearts fail Researchers have determined how metabolic pathways differ between healthy and failing hearts. Normally, a heart derives its energy from a balance of fatty acids and carbohydrates, specifically glucose. view more (2005-07-25)
Girls fare better than boys following heart surgery A recent study published in Critical Care examined the role of molecules, known as cytokines, in the recovery of children following heart surgery. The study found that girls had higher levels of cytokine IL-10, which meant that they recovered more easily from their operations than boys. In order... view more (2002-01-16)
Proteins are key to cell death in heart disease, stroke and degenerative conditions Researchers at Yale School of Medicine have gained deeper understanding of two members of a family of proteins called caspases that play a key role in promoting apoptosis, a process in which the cell responds to external signals by essentially committing suicide. view more (2006-02-23)
Safe vaccine to combat herpes infections The unpleasant and painful sores, and infection of newborn babies caused by the genital herpes virus could soon be a thing of the past according to Dr Julian Hickling, who is presenting results from Xenova Research Ltd today, Tuesday 8 April 2003, to the Society for General Microbiology's Spring... view more (2003-04-02)
Human RecQ helicases, homologous recombination and genomic instability Two independent papers in the December 1st issue of G&D detail how human RecQ helicases regulate homologous recombination and protect genome stability. view more (2007-11-15)
UCLA chemists' study of protein may provide insights into heart disease and cancer UCLA chemists studying a protein associated with a rare genetic disease may also be gaining insights into cancer and heart disease. view more (2006-08-11)
Do high dietary intakes of trans fats really promote cardiovascular disease? From his assessment of the studies, Dr John Stanley says the conclusion that trans fatty acids promote cardiovascular disease is premature for the following reasons. First, although prospective cohort studies show an association with cardiovascular disease, trans fatty acids are estimated rather... view more (1999-11-18)
New technique improves purity of medicines Dutch researcher Roelof Mol has investigated possibilities for more accurately determining the composition of medicines. He came up with a combination of two techniques that were previously considered to be incompatible: the separation technique electrokinetic chromatography (EKC) and the detection... view more (2007-10-25)
Workman Lab characterizes novel regulator of chromosome function The Stowers Institute's Workman Lab has shed new light on a novel histone acetyltransferase protein complex called ATAC. Acetyltransferases are enzymes that introduce a new acetyl functional group into histone proteins, a process by which all chromosome functions are controlled. view more (2008-03-11)
Closing holes in heart important treatment for young stroke patients, study says Placement of devices to close holes in the heart is a successful treatment for young stroke patients, finds a study involving three medical centers. view more (2006-05-18)
Sensorial evaluation of the freshness of fish AZTI has drawn up some 40 tables for freshness specific for the most important commercial species in southern Europe, including fish and shellfish. The sensorial method, known as QIM (Quality Index Method) and introduced into Europe some years ago, is being applied to a greater number of species,... view more (2005-04-18)
Lung damage in babies with congenital heart disease under study Trying to understand and stop the collateral lung damage that can occur in babies with congenital heart disease is the focus of a new study. view more (2008-03-11)
EURYI project to understand how the brain wires during embryogenesis One of the great questions of neurobiology, how the brain is built up during embryonic development, could be resolved by a young French scientist in an award winning project organised by the European Science Foundation (ESF) and the European Heads of Research Councils (EuroHORCS). view more (2007-09-24)
Swimming pool chlorine risk to pregnant women Research by Dr Mark Nieuwenhuijsen published in the journal Occupational and Environmental Medicine today (4 April) highlights an area of potential risk to pregnant women through exposure to the by-products of chlorination in swimming pools. The following statement clarifies the potential risk:... view more (2002-04-04)
Heart derived stem cells develop into heart muscle Dutch researchers at University Medical Center Utrecht and the Hubrecht Institute have succeeded in growing large numbers of stem cells from adult human hearts into new heart muscle cells. view more (2008-04-24)
Breakthrough in unravelling the causes of sudden cardiac death in young people Scientists at the Wales Heart Research Institute, Cardiff University have made a breakthrough in our understanding of the causes of sudden cardiac death (SCD) in young people. view more (2005-12-09)
Rong Li Lab probes mechanism of asymmetry in meiotic cell division The Stowers Institute's Rong Li Lab has characterized a mechanism that allows for asymmetrical cell division during meiosis in oocytes. By tracking chromosome movement in live mouse oocytes, the team discovered that chromosomes can recruit to their vicinity a protein called formin-2. view more (2008-10-08)
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