Demethylation Current Events | Demethylation News
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Growth of new brain cells requires 'epigenetic' switch
New cells are born every day in the brain's hippocampus, but what controls this birth has remained a mystery. Reporting in the January 1 issue of Science, neuroscientists at the Johns Hopkins University School of Medicine have discovered that the birth of new cells, which depends on brain activity, also depends on a protein that is involved in... view more... (2009-01-09)
Genetic Changes Outside Nuclear DNA Suspected to Trigger More Than Half of All Cancers
A buildup of chemical bonds on certain cancer-promoting genes, a process known as hypermethylation, is widely known to render cells cancerous by disrupting biological brakes on runaway growth. Now, Johns Hopkins scientists say the reverse process - demethylation - which wipes off those chemical bonds may also trigger more than half of all cancers. view more (2009-03-24)
Newly found enzymes may play early role in cancer
Researchers have discovered two enzymes that, when combined, could be involved in the earliest stages of cancer. Manipulating these enzymes genetically might lead to targeted therapies aimed at slowing or preventing the onset of tumors. view more (2008-12-29)
Researchers reveal structure of protein that repairs damage to cancer cells
A team of University of Chicago scientists has shown how two proteins locate and repair damaged genetic material inside cells. view more (2008-04-24)
Stowers Institute's Workman Lab discovers novel histone demethylase protein complex
The Stowers Institute's Workman Lab has discovered a novel histone demethylase protein complex characterized in work published today in Molecular Cell. view more (2008-12-08)
Genetic double-agents unmasked
Babraham Institute and Cancer Research UK scientists have discovered that certain enzymes with a key activity in the immune system may be important in stem-cell development, but may also work against us by contributing to the occurrence of cancer. view more (2004-10-26)
A miR boost enables acute leukemia cells to mature
A new study by Ohio State University cancer researchers shows that boosting the level of a molecule called miR-29b in acute myeloid leukemia (AML) cells can reverse gene changes that trap the cells in an immature, fast growing state of development. view more (2009-04-03)
Study finds genomic changes in the brains of people who commit suicide
Are genes destiny? Alternatively, are we simply the products of our environment? There is a growing sense that neither of these two possibilities fully captures the essence of the risk for psychiatric disorders. view more (2008-10-23)
Study finds 231 new genes associated with head and neck cancer
A Henry Ford Hospital study has identified 231 new genes associated with head and neck cancer, one of the most deadly cancers responsible for 2.1 percent of all cancer deaths in the United States. view more (2009-10-05)
Human embryonic stem cells display a unique pattern of chemical modification to DNA
Scientists from the Burnham Institute for Medical Research (BIMR) and Illumina Inc., in collaboration with stem cell researchers around the world, have found that the DNA of human embryonic stem cells is chemically modified in a characteristic, predictable pattern. view more (2006-08-07)
Novel enzyme offers new look at male hormone regulation
For the second time in less than a year, University of North Carolina at Chapel Hill scientists have purified a novel protein and have shown it can alter gene activity by reversing a molecular modification previously thought permanent. view more (2006-05-08)
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