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New approach to vaccine development provides potent, long-lasting immunity
The field of vaccine development is getting a boost from new research that has identified a promising vaccine delivery approach, which in animal studies produced long-term immune protection after just one immunization.   view more (2006-05-24)

Old mystery solved, revealing origin of regulatory T cells that 'police' and protect the body
More than 150 years after the discovery of Hassall's corpuscles in 1849, the function of these round blobs of cells in the human thymus gland has now been explained. The answer, in turn, ends an intense hunt for the origin of regulatory T cells that has been under way for years.   view more (2005-10-13)

A chemotherapy drug packs a one-two punch
Cancer can be wily, and those who treat the disease have amassed a wide array of weapons with which to fight it and kill tumors.   view more (2007-02-21)

Chemical guidance of T cells leads to immunologic memory and long-term immunity
In the latest issue of the journal Nature, scientists at the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) describe a new understanding about how long-term immunity works-findings that may lead to new ways of thinking about how to enhance... view more (2006-04-18)

Therapeutic vaccine for ovarian cancer in clinical trials
Prima BioMed (ASX: PRR) announced today at the "Thank You" Day celebration at Sydney Children's Hospital that it has completed initial recruitment of its Phase IIa clinical trial in ovarian cancer at the Austin Hospital.   view more (2005-10-12)

Mayo researchers lead team that discovers role of dendritic cells in childhood autoimmune disease
Mayo Clinic researchers, working with colleagues at the University of Minnesota and University of Pittsburgh, are the first to describe a new role for a specialized cell of the immune system in children suffering from a rare muscle-damaging disease known as juvenile dermatomyositis (JDM).   view more (2005-11-14)

Clinical trial evaluating brain cancer vaccine is underway at NYU
A clinical trial evaluating a brain cancer vaccine in patients with newly diagnosed brain cancer has begun at NYU Medical Center.   view more (2007-10-22)

Scripps research scientists devise approach that stops HIV at earliest stage of infection
Researchers at The Scripps Research Institute have developed a new two-punch strategy against HIV and they have already successfully tested aspects of it in the laboratory.   view more (2008-02-28)

A new understanding of how immune system targets disease
Scientists have taken a major step toward the goal of altering viruses, bacteria and tumor cells so that they demand attention from immune cells designed to destroy them.   view more (2005-07-27)

HIV vaccine takes different tack to boosting immune response
esearchers at Baylor College of Medicine (BCM) in Houston have reason to believe their unorthodox vaccine could one day help to prevent or control HIV infection.   view more (2006-01-03)

Researchers reverse juvenile diabetes in animal model; Clinical trial FDA approved
Groundbreaking human clinical trial for type 1 diabetes to start this spring in Pittsburgh - Children's Hospital of Pittsburgh of UPMC researchers reverse juvenile diabetes in animal model; Phase 1 clinical trial approved by FDA.   view more (2006-03-28)

Scientists directly view immune cells interacting to avert autoimmunity
Using a new form of microscopy to penetrate living lymph nodes, UCSF scientists have for the first time viewed immune cells at work, helping clarify how T cells control autoimmunity.   view more (2005-12-05)

Researchers use 'trickery' to create immune response against melanoma
A new type of immunotherapy in which dendritic cells are tricked into action against cancer when they are exposed to harmless pieces of viruses and bacteria is described in the November issue of Cancer Research.   view more (2005-11-02)

Proteins anchor memories in our brain
A University of Utah study suggests that memories are held in our brains because certain proteins serve as anchors, holding other proteins in place to strengthen synapses, which are connections between nerve cells.   view more (2006-11-22)

How the Neuron Sprouts Its Branches
Neurobiologists have gained new insights into how neurons control growth of the intricate tracery of branches called dendrites that enable them to connect with their neighbors.   view more (2005-12-12)

'Underground' tunnels discovered as means for communication between immune system cells
Immune system cells are connected to each other by an extensive network of tiny tunnels that, like a building's hidden pneumatic tube system, are used to shoot signals to distant cells.   view more (2005-09-21)

New nano device detects immune system cell signaling
Scientists have detected previously unnoticed chemical signals that individual cells in the immune system use to communicate with each other over short distances.   view more (2008-09-04)

Commonly used antidepressants may also affect human immune system
Drugs that treat depression by manipulating the neurotransmitter serotonin in the brain may also affect the user's immune system in ways that are not yet understood, say scientists from Georgetown University Medical Center and a Canadian research institute.   view more (2006-01-20)

Sounding the alarm for infections: EMBL researchers discover rapid-response, interferon-producing cells
Nearly fifty years ago, researchers discovered that when cells in laboratory cultures are infected by a virus, they secrete a substance that protects other cells from infection. In 1957 Alick Issaks and Jean-Jacques Lindenmann traced this effect to a protein called interferon, a molecule now known... view more (2002-02-15)

The multi-tasking reovirus
In the past couple of years, researchers at Oncolytics Biotech have been developing a harmless virus as a potent cancer killer, but they have also been accumulating data that suggests in addition to directly killing tumor cells, the reovirus may prime the immune system to mount a separate, powerful... view more (2007-02-08)

Meth Promotes Spread of Virus in HIV-Infected Users
Researchers at the University at Buffalo have presented the first evidence that the addictive drug methamphetamine, or meth, also commonly known as "speed" or "crystal," increases production of a docking protein that promotes the spread of the HIV-1 virus in infected users.   view more (2006-08-07)

Pancreatic cancer vaccine halts progression of disease in some patients
A dendritic cell-based therapeutic vaccine for pancreatic cancer developed by researchers at the University of Pittsburgh School of Medicine has successfully stalled the disease from progressing in a handful of patients three years post-vaccination.   view more (2007-04-18)

Lymph nodes harbor information on whether breast cancer will recur
Breast cancer often spreads through the lymph nodes in the arm pits (so-called axillary lymph nodes), and whether these lymph nodes are tumor-free or contain small metastases is an important factor in the decision of how aggressively to treat a patient.   view more (2005-09-06)

A new view of drugs used to treat rheumatoid arthritis
Powerful drugs used to treat patients with rheumatoid arthritis have a profound, previously unrecognized effect on the immune system, breaking up molecular "training camps" for rogue cells that play an increasingly recognized role in autoimmune diseases like rheumatoid arthritis and lupus.   view more (2008-01-21)

New target for HIV/AIDS drugs and vaccines discovered
Researchers from Rome, Italy, describe a finding in the August 2007 print issue of The FASEB Journal that could lead to new drugs to fight the HIV/AIDS virus, as well as new vaccines to prevent infection.   view more (2007-07-27)
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