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New target for HIV/AIDS drugs and vaccines discovered
Researchers from Rome, Italy, describe a finding in the August 2007 print issue of The FASEB Journal that could lead to new drugs to fight the HIV/AIDS virus, as well as new vaccines to prevent infection.   view more (2007-07-27)

Novel vaccine shows promise against early-stage breast cancer
A diagnosis of breast cancer has taken on a new meaning in the past 10 years, as research has produced a host of new therapies and detection techniques, significantly improving long-term survival for women who have been fighting the disease.   view more (2006-11-13)

New discoveries about neuron plasticity linked to learning and memory
Neurons experience large-scale changes across their dendrites during learning, say neuroscientists at The University of Texas at Austin in a new study that highlights the important role that these cell regions may play in the processes of learning and memory.   view more (2005-11-02)

UCR researchers propose minocycline as a promising drug for patients with Fragile X syndrome
A UC Riverside-led team of biomedical scientists has found that a readily available drug called minocycline, used widely to treat acne and skin infections, can be used to treat Fragile X syndrome, the most common inherited cause of mental impairment and the most common cause of autism.   view more (2008-10-03)

New vaccine protects more effectively against tuberculosis
Globally, tuberculosis remains the number one killer in adults. Moreover, multi-drug-resistant tuberculosis strains are on the rise which cannot be treated by first-line drugs.   view more (2005-08-29)

Cellular pathway yields potential new weapon in vaccine arsenal
When a cell has to destroy any of its organelles or protein aggregates, it envelopes them in a membrane, forming an autophagosome, and then moves them to another compartment, the lysosome, for digestion. Two years ago, Rockefeller University assistant professor Christian Münz showed that this... view more (2006-12-27)

RNA-associated introns guide nerve-cell channel production
Researchers at the University of Pennsylvania School of Medicine have discovered that introns, or junk DNA to some, associated with RNA are an important molecular guide to making nerve-cell electrical channels.   view more (2008-02-06)

Communication within the immune system:Immune synapses cannot function without ZAP-70
A familial form of severe combined immune deficiency (SCID) is caused by anomalies of an enzyme called ZAP-70. If ZAP-70 is lacking or does not work, the T-cells, which play a key role in the mechanisms of immune defense, are no longer functional. Affected children therefore catch infections as... view more (2002-10-24)

OHSU Cancer Institute finds that drug stimulated immune system in prostate cancer
In a multi-site study, Oregon Health & Science University Cancer Institute researchers have found that a drug called Ipilimumab, also known as MDX-010, works to stimulate the body's own immune system to fight prostate cancer. The drug was found to be effective in study participants with a... view more (2008-06-03)

Reagent under study as cancer vaccine may also help protect tumors
A bacterial mimic under study as a cancer vaccine because it signals the immune system to attack may also help some tumors hide, researchers have found.   view more (2005-11-01)

Hormonal signaling in the brain: radical shift in understanding information processing
Two University of Edinburgh professors from the Centre for Integrative Physiology describe how "our understanding of how the brain processes information is undergoing a radical shift as we begin to recognize the implications of hormonal signaling systems within the brain itself,"... view more (2005-07-20)

The road to allergy
A UK scientist has discovered the route and type of transport taken by peanut proteins through the gut to the immune system. This route favours an immune response, which helps explain why peanuts are one of the most allergenic foods.   view more (2004-11-18)

Scripps scientists studying sepsis in mice find potential drug targets for deadly disease
"We have identified a key connection of signaling pathways in the cascade of events leading to sepsis. This defines a crucial point where the immune system spirals out of control to cause severe sepsis and where there is an opportunity for therapeutic intervention," says Scripps Research... view more (2008-02-28)

Stopping a receptor called 'nogo' boosts the synapses
New findings about a protein called the nogo receptor are offering fresh ways to think about keeping the brain sharp.   view more (2008-03-19)

Rim of Crater Huygens on Mars
These images, taken by the High Resolution Stereo Camera (HRSC) on board ESA's Mars Express spacecraft, show the eastern rim of the Martian impact crater Huygens.   view more (2004-10-19)

Neuroscientists Show Insulin Receptor Signaling Regulates Structure and Function of Brain Circuits
A team of neuroscientists at Cold Spring Harbor Laboratory (CSHL) has demonstrated for the first time in living animals that insulin receptors in the brain can initiate signaling that regulates both the structure and function of neural circuits.   view more (2008-06-19)

Tiny RNA molecules fine-tune the brain's synapses
Non-coding regions of the genome - those that don't code for proteins - are now known to include important elements that regulate gene activity.   view more (2006-01-19)

Understanding the migration of cancer cells
Lamellipodia are veil-shaped protrusions of the plasma membrane, that can turn into upward-curled ruffles if they fail to adhere to the substrate.   view more (2008-06-23)

MIT researcher finds neuron growth in adult brain
Despite the prevailing belief that adult brain cells don't grow, a researcher at MIT's Picower Institute for Learning and Memory reports in the Dec. 27 issue of Public Library of Science (PLoS) Biology that structural remodeling of neurons does in fact occur in mature brains.   view more (2005-12-27)

Head and neck cancer vaccine targets proteins to create immune response
Most attempts to create therapeutic cancer vaccines are based on custom-made approaches that use a patient's own tumor cells to generate a strong immune response against cancer. However, developing these kinds of personalized vaccines is time-consuming, expensive and often impractical.   view more (2007-04-18)

Schizophrenia-linked gene keeps new adult brain cells under control
A gene with reported links to schizophrenia and other mood disorders plays a broader role in the brain than scientists had previously suspected.   view more (2007-09-07)

Specialized white blood cells coordinate first responders to viral infection
Just as fire engines arrive quickly at the scene to save people and property, the cells that fight viruses have to reach the site of an infection promptly to mount a protective response.   view more (2008-04-25)

Deficiency of immune system 'peacekeeper' pinpointed in mice as cause of ulcerative colitis
In a series of mouse experiments, researchers at the Harvard School of Public Health (HSPH) have pinpointed a specific immune deficiency as the likely fundamental cause of ulcerative colitis, a chronic, sometimes severe inflammatory disease of the colon or large intestine that afflicts half a... view more (2007-10-05)

Scientists learn role of oxidative stress in estrogen-related bone loss
Scientists have discovered new information about an immune pathway in mice that explains how oxidative stress that results from acute estrogen deficiency leads to the loss of bone.   view more (2007-09-11)

How breastfeeding affects HIV transmission
Mother to child transmission of HIV accounts for a large proportion of HIV infections in children, with many infected as a result of breastfeeding, which requires transfer of the virus across mucosal barriers.   view more (2005-10-21)
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