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OHSU Cancer Institute finds that drug stimulated immune system in prostate cancer
In a multi-site study, Oregon Health & Science University Cancer Institute researchers have found that a drug called Ipilimumab, also known as MDX-010, works to stimulate the body's own immune system to fight prostate cancer. The drug was found to be effective in study participants with a serious type of prostate cancer - one where the tumor... view more... (2008-06-03)

Hormonal signaling in the brain: radical shift in understanding information processing
Two University of Edinburgh professors from the Centre for Integrative Physiology describe how "our understanding of how the brain processes information is undergoing a radical shift as we begin to recognize the implications of hormonal signaling systems within the brain itself," explained Gareth Leng.   view more (2005-07-20)

Reagent under study as cancer vaccine may also help protect tumors
A bacterial mimic under study as a cancer vaccine because it signals the immune system to attack may also help some tumors hide, researchers have found.   view more (2005-11-01)

The road to allergy
A UK scientist has discovered the route and type of transport taken by peanut proteins through the gut to the immune system. This route favours an immune response, which helps explain why peanuts are one of the most allergenic foods.   view more (2004-11-18)

CSHL researchers unravel how a protein helps nerve cells recycle synaptic vesicles
Brain cells, or neurons, transmit electrical signals efficiently only when they recycle tiny cellular sacs that store signaling chemicals called neurotransmitters.   view more (2009-06-03)

Study reveals current multi-component vaccines may need reworking
Current strategies for designing vaccines against HIV and cancers, for instance, may enable some components in multi-component vaccines to cancel the effect of others on the immune system, eliminating their ability to provide protection, according to an article to be published shortly in the Proceedings of the National Academy of Sciences (PNAS).   view more (2009-05-08)

Rim of Crater Huygens on Mars
These images, taken by the High Resolution Stereo Camera (HRSC) on board ESA's Mars Express spacecraft, show the eastern rim of the Martian impact crater Huygens.   view more (2004-10-19)

Scripps scientists studying sepsis in mice find potential drug targets for deadly disease
"We have identified a key connection of signaling pathways in the cascade of events leading to sepsis. This defines a crucial point where the immune system spirals out of control to cause severe sepsis and where there is an opportunity for therapeutic intervention," says Scripps Research Professor Wolfram Ruf, who led the research with... view more... (2008-02-28)

Stopping a receptor called 'nogo' boosts the synapses
New findings about a protein called the nogo receptor are offering fresh ways to think about keeping the brain sharp.   view more (2008-03-19)

Team develops DNA compounds that could help treat lupus
A research team led by a University of Iowa investigator has generated DNA-like compounds that effectively inhibit the cells responsible for systemic lupus erythematosus -- the most common and serious form of lupus.   view more (2009-05-28)

Neuroscientists Show Insulin Receptor Signaling Regulates Structure and Function of Brain Circuits
A team of neuroscientists at Cold Spring Harbor Laboratory (CSHL) has demonstrated for the first time in living animals that insulin receptors in the brain can initiate signaling that regulates both the structure and function of neural circuits.   view more (2008-06-19)

Sperm may play leading role in spreading HIV
Sperm, and not just the fluid it bathes in, can transmit HIV to macrophages, T cells, and dendritic cells (DCs), report a team led by Ana Ceballos at the University of Buenos Aires in Argentina.   view more (2009-10-26)

Computer simulation captures immune response to flu
Researchers have successfully tested first the first time a computer simulation of major portions of the body's immune reaction to influenza type A, with implications for treatment design and preparation ahead of future pandemics, according to work accepted for publication, and posted online, by the Journal of Virology.   view more (2009-05-19)

Tiny RNA molecules fine-tune the brain's synapses
Non-coding regions of the genome - those that don't code for proteins - are now known to include important elements that regulate gene activity.   view more (2006-01-19)

Scientists learn why even treated genital herpes sores boost the risk of HIV infection
New research helps explain why infection with herpes simplex virus-2 (HSV-2), which causes genital herpes, increases the risk for HIV infection even after successful treatment heals the genital skin sores and breaks that often result from HSV-2.   view more (2009-08-03)

Neurons found to be similar to Electoral College
A tiny neuron is a very complicated structure. Its complex network of dendrites, axons and synapses is constantly dealing with information, deciding whether or not to send a nerve impulse, to drive a certain action.   view more (2009-09-15)

Understanding the migration of cancer cells
Lamellipodia are veil-shaped protrusions of the plasma membrane, that can turn into upward-curled ruffles if they fail to adhere to the substrate.   view more (2008-06-23)

APP -- Good, bad or both?
New data about amyloid precursor protein, or APP, a protein implicated in development of Alzheimer's disease, suggests it also may have a positive role -- directly affecting learning and memory during brain development.   view more (2009-10-19)

MIT researcher finds neuron growth in adult brain
Despite the prevailing belief that adult brain cells don't grow, a researcher at MIT's Picower Institute for Learning and Memory reports in the Dec. 27 issue of Public Library of Science (PLoS) Biology that structural remodeling of neurons does in fact occur in mature brains.   view more (2005-12-27)

Scientists show how a neuron gets its shape
Ask a simple question, get a simple answer: When Abraham Lincoln was asked how long a man's legs should be, he absurdly replied, "Long enough to reach the ground." Now, by using a new microscopy technique to watch the growth of individual neurons in the microscopic roundworm Caenorhabditis elegans, Rockefeller University researchers are... view more... (2009-04-06)
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