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Genome circularization and RNA virus replication
As featured on the cover of the August 15th issue of G&D, an Argentinian research team, led by Dr. Andrea Gamarnik, report on their recent discovery of a novel mechanism of dengue virus replication.   view more (2006-08-01)

Gene expression profiling of dengue virus infection in cell lines and patients
Researchers at the Novartis Institute for Tropical Diseases and the Genome Institute of Singapore have identified new host genes associated with dengue virus infection, which may open new avenues to developing a drug to treat the disease.   view more (2007-11-07)

Computer Models Aid Understanding of Antibody-Dependent Enhancement in Spread of Dengue Fever
Some viruses' ability to exploit the human body's own defenses to increase their replication may be both a blessing and curse, according to the findings of a study conducted by researchers at the Johns Hopkins Bloomberg School of Public Health.   view more (2005-10-17)

Lower transmission increases dengue deaths
A pair of researchers has answered a puzzle about why efforts to lower the transmission of dengue virus in Thailand have not resulted in decreases in the severe, life-threatening, form of the infection. In fact, it seems to have had just the opposite effect.   view more (2008-02-05)

Smaller mosquitoes are more likey to be infected with viruses causing human diseases
An entomologist at the Illinois Natural History Survey, a division of the new UI Institute for Natural Resource Sustainability, says smaller mosquitoes are more likely to be infected with viruses that cause diseases in humans.   view more (2008-11-04)

The cost of dengue fever challenges public health and national economies
A new study of the disease burden of dengue fever in Malaysia strengthens the case for development of a vaccine against the mosquito-borne illness.   view more (2005-07-07)

Substantial costs and underreporting of dengue fever, concerns about blood supply face US
Dengue fever, known as "breakbone fever" because of the excruciating back and joint pain that accompanies this infectious disease, is a growing public health threat for people living in tropical countries, as well as travelers to destinations such as Thailand, Brazil and Puerto Rico.   view more (2007-10-17)

Severe dengue infections may go unrecognized in international travelers
Severe cases of a common travelers' infection may not be recognized if doctors rely on the World Health Organization's (WHO) guidelines for identifying it.   view more (2007-03-27)

New Mosquito Control Strategy Proves Successful Against Dengue Fever
Over 380,000 people have been protected from dengue fever in Vietnam thanks to the implementation of a novel strategy to control mosquitoes in the country, concludes a report in this week's issue of THE LANCET.   view more (2005-02-09)

Genetically engineered mosquitoes show resistance to dengue fever virus
Researchers have successfully created a genetically engineered mosquito that shows a high level of resistance against the most prevalent type of dengue fever virus, providing a powerful weapon against a disease that infects 50 million people each year.   view more (2006-03-09)

Biologists visualize protein interaction that may initiate viral infection
Biologists at Purdue University have taken a "snapshot" of a Velcro-like protein on a cell's surface just after it attached to the dengue virus, a linkup thought to initiate the early stages of infection.   view more (2006-02-10)

Dengue Virus Reveals Its Circular Secret
The first step in the transmission of mosquito-borne viruses is no mystery: it's the pesky insect's bite that allows the virus to enter its victim's bloodstream. But for some of the most dangerous insect-borne viruses, details of what happens next have been unclear.   view more (2006-08-02)

Simple idea to dramatically improve dengue vaccinations
An innovative new study explains, for the first time, the failure of previous attempts to vaccinate against the four known Dengue viruses, and it suggests a very simple solution - injecting the four vaccines simultaneously at different locations on the body.   view more (2006-03-30)

DENGUE FEVER IN THAILAND: HOW TO SPOT EPIDEMICOUTBREAKS AGAINST THE ENDEMIC BACKGROUND
Dengue is a viral disease which is prevalent in a hundred or so tropical countries. Up to 50 million cases have been recorded each year in the world according to WHO. It is in fact induced by four viruses (Dengue serotypes 1, 2, 3 and 4) belonging to the flavivirus family. The mosquito Aedes... view more (1999-09-13)

NIAID experts see dengue as potential threat to US public health
A disease most Americans have never heard of could soon become more prevalent if dengue, a flu-like illness that can turn deadly, continues to expand into temperate climates and increase in severity, according to a new commentary by Anthony S. Fauci, M.D., director of the National Institute of... view more (2008-01-09)

UGA study explains peaks and troughs of dengue epidemics
Scientists have long known that epidemics of dengue fever wax and wane over a period of several years, but they've never been quite sure why.   view more (2006-07-31)

Dengue and other hemorrhagic fevers: Towards a first potential treatment
Globally, 60 to 100 million people are hit by Dengue, a viral disease transmitted by mosquitoes of the genus Aedes. The most severe form of this disease, which causes blood loss, can lead to a fatal shock-like state (Dengue Shock Syndrome) with or without associated haemorrhage, and is currently... view more (2006-12-26)

Secrets to antibody's success against West Nile Virus surprise scientists
A monoclonal antibody that can effectively treat mice infected with West Nile virus has an intriguing secret: Contrary to scientists' expectations, it does not block the virus's ability to attach to host cells.   view more (2005-09-29)

Discovery may help defang viruses
Researchers may be able to tinker with a single amino acid of an enzyme that helps viruses multiply to render them harmless, according to molecular biologists who say the discovery could pave the way for a fast and cheap method of making vaccines.   view more (2007-08-29)

Disease-free mosquito bred to disease-carrier can have all disease-free progeny
A decade ago, scientists announced the ability to introduce foreign genes into the mosquito genome. A year ago, scientists announced the successful use of an artificial gene that prevented a virus from replicating within mosquitoes.   view more (2007-07-18)

Ayurvedic nightshade deadly for dengue mosquito
Mosquitoes responsible for spreading disease are increasingly becoming resistant to synthetic insecticides. Now research published in the online open access journal BMC Complementary and Alternative Medicine suggests that the berries of a weed common to India, Solanum villosum (S villosum), have... view more (2008-04-03)

Findings reveal how dengue virus matures, becomes infectious
Biologists at Purdue University have determined why dengue virus particles undergo structural changes as they mature in host cells and how the changes are critical for enabling the virus to infect new host cells.   view more (2008-03-28)

West Nile virus antibodies sought in birds in England
Scientists at the Centre for Ecology and Hydrology at Oxford are investigating live birds to see whether or not West Nile virus is present and being actively transmitted between resident and migratory birds. No infectious virus has as yet been detected. The birds sampled were healthy, implying... view more (2002-10-31)

New West Nile and Japanese encephalitis vaccines produced
University of Texas Medical Branch at Galveston researchers have developed new vaccines to protect against West Nile and Japanese encephalitis viruses. The investigators created the vaccines using an innovative technique that they believe could also enable the development of new vaccines against... view more (2008-05-30)

Rotavirus can spread beyond the intestine
A new study in PLoS Medicine has shown that children who have rotavirus, a very common cause of diarrhea in children, and who have antigens (protein fragments from the surface of the virus) in their blood, also have infectious virus in their blood.   view more (2007-04-17)
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