Dexamethasone Current Events | Dexamethasone News
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Multiple myeloma clinical trial closes early
Mayo Clinic Cancer Center announced today that a multiple myeloma clinical trial has shown a significant improvement in survival with lenalidomide plus low-dose dexamethasone therapy compared to lenalidomide plus high-dose dexamethasone. view more (2007-04-05)
Large dose dexamethasone plays important roles in severe acute pancreatitis
Severe acute pancreatitis (SAP) is a fatal systemic disease featuring acute onset, serious conditions, high incidence of complications and 20 - 30% mortality, mainly due to multiple organ failure at its early stage. view more (2007-11-05)
REVLIMID improves overall survival and delays disease progression in multiple myeloma patients
Celgene Corporation (NASDAQ: CELG) announced updated clinical data from two Phase III pivotal studies evaluating REVLIMID (lenalidomide) plus dexamethasone in previously treated multiple myeloma patients. view more (2005-12-13)
Prenatal exposure to glucocorticoids has long-term deleterious effects on newborns
Researchers at the University of Edinburgh in the United Kingdom have found that, as for rodents and other nonprimates, prenatal exposure of nonhuman primate African vervet monkeys (Chloroceus aethiops) to glucocorticoids has long-lasting deleterious effects on cardiovascular, metabolic, and neuroendocrine function. view more (2007-03-23)
Analysis shows revlimid plus dexamethasone increases overall survival in multiple myeloma patients
Celgene International Sarl (NASDAQ: CELG) announced that data from a landmark analysis of patients with relapsed/refractory multiple myeloma found that continuous treatment with REVLIMID (lenalidomide) in combination with dexamethasone after achieving best response resulted in significantly longer overall survival and increased time to disease... view more... (2008-12-11)
Mayo Clinic research shows promise for myeloma patients
Mayo Clinic Cancer Center investigators report that combination therapy with lenalidomide (RevlimidTM) and dexamethasone (combination is called Rev/Dex) looks like a breakthrough treatment for multiple myeloma. view more (2005-09-02)
Taking dex can improve high altitude exercise capacity in certain climbers
Taking dexamathasone prophlyactically may improve exercise capacity in some mountaineers, according to Swiss researchers. Dexamathasone, known popularly to climbers as "dex," has been used for years to treat altitude-related symptoms in mountaineers, but has never been tested for its ability to improve exercise capacity at high altitude. view more (2009-08-12)
Penn's Abramson Cancer Center part of major phase III study for myeloma
Researchers from the Abramson Cancer Center of the University of Pennsylvania announced today that findings from two large, international clinical trials show unprecedented survival for patients with multiple myeloma, a cancer that occurs in the blood-making cells of bone marrow. view more (2007-11-26)
First-degree fetal heart block may be reversible
There is an increased risk of fetal heart problems when mothers carry particular antibodies associated with rheumatic diseases, according to an abstract presented by Yale School of Medicine researchers at the Society for Maternal-Fetal Medicine Conference February 9 in San Francisco. view more (2007-02-12)
Steroids Not as Effective in Obese Asthma Patients
Researchers at National Jewish Health have shown that glucocorticoids, the primary controller medication for asthma, are 40 percent less effective in overweight and obese asthma patients than in those of normal weight. view more (2008-09-17)
Change policy: Giving steroids to children with meningitis can reduce hearing loss and lower the incidence of long-term brain damage and can save lives in both children and adults with meningitis
Research News in the Cochrane Database of Systematic Reviews Antibiotics are essential and life-saving in the treatment of bacterial meningitis, but for years doctors have debated whether to give corticosteroids at the same time. The inflammation caused by meningitis can actually be made worse by antibiotics in the short term, as the bacteria... view more... (2003-09-23)
Change policy: Giving steroids to children with meningitis can reduce hearing loss and lower the incidence of long-term brain damage and can save lives in both children and adults with meningitis
Research News in the Cochrane Database of Systematic Reviews Antibiotics are essential and life-saving in the treatment of bacterial meningitis, but for years doctors have debated whether to give corticosteroids at the same time. The inflammation caused by meningitis can actually be made worse by antibiotics in the short term, as the bacteria... view more... (2003-07-28)
Vitamin supplement could help treatment-resistant asthma
Asthma patients who don't respond to steroid treatment suffer repeated asthma attacks, and are at greater risk of dying from the condition. view more (2005-12-09)
3-drug combination 'extremely promising' as first-line therapy for multiple myeloma
A new combination of bortezomib (Velcade) and two other drugs is showing a very high response rate in patients newly diagnosed with multiple myeloma, a team headed by Dana-Farber Cancer Institute investigators reported at the annual meeting of the American Society of Hematology. view more (2007-12-12)
Blood pressure drug curbs brain damage from PTSD
A drug used to treat high blood pressure and enlargement of the prostate may protect the brain from damage caused by post-traumatic stress disorder, Alzheimer's disease, depression and schizophrenia. view more (2007-11-07)
Promising results from 2 trials highlighting pomalidomide presented at ASH
Celgene International Sarl (Nasdaq: CELG) today announced that its next IMiDs compound, pomalidomide, has shown promising activity with manageable safety and tolerability for the treatment of relapsed/refractory multiple myeloma (MM) and myelofibrosis. view more (2008-12-11)
DEMAND FOR GREATER REGULATION OF CHINESE HERBALISTS
In their study of Chinese herbal remedies obtained by patients for the treatment of dermatological conditions, Keane et al found that eight of the eleven creams tested contained a prescription only steroid (Dexamethasone) - the prescription of which by unauthorised people is illegal in the UK. Furthermore the concentration of the steroid in the... view more... (1999-02-26)
Long-lasting Nerve Block Could Change Pain Management
Researchers at Children's Hospital Boston have developed a slow-release anesthetic drug-delivery system that could potentially revolutionize treatment of pain during and after surgery, and may also have a large impact on chronic pain management. view more (2009-04-16)
Thalidomide treatment proves better than conventional chemotherapy for multiple myeloma
When people hear "thalidomide," many think "birth defects," however, evidence has come to light that this once-banned drug can be used as a potent anti-cancer treatment. In a new study, researchers from the University of Bologna, Italy, demonstrate that Thal-Dex (thalidomide used in combination with dexamethasone) is more... view more... (2005-06-21)
Novel therapeutic approaches may improve patient outcomes in several platelet disorders
Four studies that highlight significant advances in treatment and survival outcomes for patients with various forms of thrombocytopenia, a group of bleeding disorders characterized by a low number of platelets in the blood. view more (2008-12-08)
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