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Penn Scientists Map Molecular Regulation of Fat-Cell Genetics
A research team led by Mitchell Lazar, MD, PhD, Director of the Institute for Diabetes, Obesity, and Metabolism at the University of Pennsylvania School of Medicine, has used state-of-the-art genetic technology to map thousands of positions where a molecular "master regulator" of fat-cell biology is nestled in DNA to control genes in... view more... (2008-11-05)

All tied up: Tethered protein provides long-sought answer
The tools of biochemistry have finally caught up with lactose repressor protein. Biologists from Rice University in Houston and the University of Florence in Italy this week published new results about "lac repressor," which was the first known genetic regulatory protein when discovered in 1966.   view more (2009-09-23)

Handheld DNA detector
A researcher at the National University at San Diego has taken a mathematical approach to a biological problem - how to design a portable DNA detector.   view more (2008-03-11)

Finding that 1-in-a-billion that could lead to disease
Errors in the genetic code can give rise to cancer and a host of other diseases, but finding these errors can be more difficult than looking for the proverbial needle in the haystack.   view more (2007-08-20)

Cash boost for research into leukaemia
Scientists from the University of Sussex in Brighton have been awarded £147,000 by the Leukaemia Research Fund (LRF) to look at abnormalities in DNA damage and repair that occur in some leukaemias and lymphomas. The research team ¾ led by Dr Penny Jeggo at the Genome Damage and Stability Centre ¾ will look at Seckel Syndrome, a rare... view more... (2002-09-11)

DNA-Proofed Documents To Arrive 'By 2006'
The commercial launch of the first ever fool-proof document security system is planned for 2006, reports Marina Murphy in Chemistry & Industry magazine. The system, which uses DNA fingerprinting, will allow documents to be authenticated with an accuracy of billions to one against duplication, according to the Australian scientists working on... view more... (2004-06-17)

ISU researcher identifies key function in protein, cell transcription
When cells decide to make proteins, key building blocks of all organisms, they need to know where to start reading the instructions for assembling them.    view more (2009-05-04)

Mothers transmit DNA through daughters only
Scientists have argued whether or not the often-studied mitochondrial DNA molecule is clonally inherited. It is with assuming clonal inheritance this type of DNA has been used to track the origin of modern human as well as to draw pictures of genetic relationships among other animals and plants. The conflict has now been solved by two evolutionary... view more... (2001-09-06)

Professor sheds light on DNA mechanisms
By manipulating individual atoms in DNA and forming unique molecules, a Georgia State University researcher hopes to open new avenues in research towards better understanding the mechanisms of DNA replication and transcription, and perhaps leading to new treatments for diseases.   view more (2009-07-20)

Faster, more cost-effective DNA test for crime scenes, disease diagnosis
Scientists in Japan are reporting development of a faster, less expensive version of the fabled polymerase chain reaction (PCR) a DNA test widely used in criminal investigations, disease diagnosis, biological research and other applications.   view more (2009-07-09)

New non-viral vector for gene therapy
A research team from the Universitat Autònoma de Barcelona has designed and built a recombinant protein (synthesised from artificially linked DNA segments) which is capable of releasing genes in specific cells. The new protein is ten times more efficient than the synthetic genetic vehicles in use until now and avoids the risks associated... view more... (2000-06-26)

UT Southwestern researchers identify new targets for RNAs that regulate genes
Tiny strands of genetic material called RNA - a chemical cousin of DNA - are emerging as major players in gene regulation, the process inside cells that drives all biology and that scientists seek to control in order to fight disease.   view more (2008-07-07)

New research promises cure by mouth
A researcher at Aston University in Birmingham has become the first in the UK to investigate a new type of vaccination delivery that could revolutionise how we are protected against diseases including flu, hepatitis and, most excitingly, cancer. Dr Yvonne Perrie from the School of Life & Health Sciences has received a research grant from The... view more... (2002-12-02)

University of Minnesota researchers take new look at cellular suicide
Like a bodyguard turned traitor, a protein whose regular job is to help repair severed DNA molecules will, in some cases, join forces with another protein to do the opposite and chop the DNA to bits.   view more (2006-07-07)

Technique finds gene regulatory sites without knowledge of regulators
A new statistical technique developed by researchers at the University of Illinois allows scientists to scan a genome for specific gene-regulatory regions without requiring prior knowledge of the relevant transcription factors.   view more (2009-11-20)

Protein helps cells duplicate correctly, avoid becoming cancer
A Purdue University researcher has discovered that the absence of certain proteins needed for proper cell duplication can lead to cancer.    view more (2009-10-06)

Selfing DNA prevents genomes from mixing
Genomes of multicellular organisms are one of the greatest mysteries of biology. The more is discovered about them, the more questions are to be answered. One of such questions is connected with the size of a genome. As is known since the middle of the 20th century, the level of organization of an organism does not depend on the genome size, i.e.,... view more... (2002-10-11)

Milestone tumor virus publication by Elsevier journal Virology
A recent special edition of the Elsevier journal Virology reviews the past, present, and future of the exciting field of small DNA tumor viruses.   view more (2009-04-10)

Researchers gain insight into mechanism underlying Huntington's
Researchers at the University of Kentucky Markey Cancer Center and Graduate Center for Toxicology (GCT) have gained new insight into the genetic mechanisms underlying Huntington's disease and other neurodegenerative or neuromuscular disorders caused by trinucleotide repeats (or TNRs) in DNA.   view more (2009-07-14)

Gene for neat repair of DNA discovered
Researchers from the Erasmus University in Rotterdam have demonstrated that a gene helps in the neat repair of DNA. Without this gene the body would repair damaged DNA in a careless manner more often. This causes new damage, which can lead to cancer. The careless repair of damaged DNA can cause mutations and can result in cancer. Cell biologists... view more... (2002-01-24)
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