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Gene Test Could Reduce Unnecessary Treatment For Women With Breast Cancer (pp 340, 362)
In this week's issue of THE LANCET, US researchers describe how gene expression profiles could determine whether or not women with breast cancer would respond to docetaxel treatment. Women who are likely to be resistant to the drug could be given alternative treatment. Chemotherapy or hormonal... view more (2003-07-30)
Molecular fingerprint of breast-cancer drug resistance can predict response to treatment
A way of predicting which patients will respond well to treatment with a common chemotherapy drug used in breast cancer was unveiled at the European Cancer Conference (ECCO 14) today (Monday 24 September). view more (2007-09-25)
Docetaxel versus paclitaxel in breast cancer - results of world's first head to head trial
Embargoed: 09.00 hrs CET Wednesday 24 September 2003 view more (2003-09-21)
New chemotherapy combo produces side effects, but no extra efficacy, in early breast cancer patients
Adding capecitabine, a drug that inhibits DNA synthesis and slows the growth of tumour tissue, to docetaxel, in patients with early breast cancer, leads to more toxicities and does not improve the efficacy of treatment. view more (2008-04-17)
Studies suggest key correlation between lung cancer subtype and treatment outcomes
In clinical research, patients with advanced non-small cell lung cancer (NSCLC) that are classified as having a non-squamous histology achieve statistically significant higher survival when treated in the second-line setting with ALIMTA® (pemetrexed for injection) when compared to... view more (2007-09-27)
Hormone inhibitor promising for hard-to-treat prostate cancer
For prostate cancer patients whose tumors have continued to grow despite medical or surgical castration, a new drug candidate that inhibits production of male hormones anywhere in the body is showing promise in early trials. view more (2007-07-09)
OHSU Cancer Institute researchers find novel chemo drug helps treat prostate cancer
Men with a certain type of prostate cancer have been shown to respond to a new chemotherapy drug, Sagopilone, plus prednisone in an international trial led by Oregon Health & Science University Cancer Institute researchers. view more (2008-06-02)
OHSU Cancer Institute researcher identifies protein that helps predict prostate cancer survival
An Oregon Health & Science University Cancer Institute researcher has identified a protein that is a strong indicator of survival for men with advanced prostate cancer. The C-reactive protein, also known as CRP, is a special type of protein produced by the liver that is elevated in the presence... view more (2008-04-23)
Vitamin D, taxotere combination extends the lives of men with advanced prostate cancer
Men with advanced prostate cancer who take an experimental, high-dose vitamin D pill with chemotherapy live about eight months longer than those receiving chemotherapy and placebo. view more (2005-11-03)
Iressa proves just as effective as chemotherapy for lung cancer
Gefitinib, also known as Iressa, the once-promising targeted therapy for the treatment of non-small cell lung cancer, has proven as effective as chemotherapy as a second-line therapy for the disease with far fewer side effects, according to an international Phase III clinical trial, led by... view more (2008-11-21)
Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial
A molecular "off" switch packaged in a tiny sphere penetrates deeply into ovarian cancer tumor cells, stifling a troublesome protein and drastically reducing the size of tumors. view more (2006-08-15)
Researchers identify and shut down protein that fuels ovarian cancer
A protein that stimulates blood vessel growth worsens ovarian cancer, but its production can be stifled by a tiny bit of RNA wrapped in a fatty nanoparticle, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in the Journal of the National Cancer... view more (2008-02-27)
OHSU Cancer Institute research gives hope for chemo holidays for men with advanced prostate cancer
Oregon Health & Science University Cancer Institute researchers, in a first-of-its-kind study, have found that even men with advanced prostate cancer can take a much-needed safe break, or holiday, from chemotherapy. view more (2008-02-26)
Researchers announce new predictor for lung cancer treatment and survival
Research from the Ireland Cancer Center of University Hospitals of Cleveland has found a promising, novel biomarker that may be used to predict the survival of patients with advanced lung cancer and their response to treatment. view more (2006-06-06)
Novel mechanism of taxane resistance
Research Associate Chih-Jian Lih and others working in the laboratory of Dr. Stanley N. Cohen at Stanford University have pinpointed a gene that affects human cancer cells' sensitivity to chemotherapy-an important finding in the effort to increase the effectiveness of chemotherapy. view more (2006-07-17)
New Herceptin results confirm impressive reduction in risk of cancer returning
New Herceptin results confirm impressive reduction in risk of cancer returning in women with aggressive form of early-stage breast cancer. view more (2005-09-14)
Prostate cancer research may be faster with PSA endpoints
A new study from Columbia University Medical Center researchers at NewYork-Presbyterian Hospital/Columbia, who are members of the Southwest Oncology Group (SWOG), suggests that certain changes in prostate-specific antigen (PSA) levels may serve as surrogate endpoints for prostate cancer survival. view more (2006-04-19)
Treatment-induced growth factor causes cancer progression
In advanced cancer, anti-tumor therapies often work only partially or not at all, and tumors progress following treatment. view more (2007-04-06)
To evade chemotherapy, some cancer cells mimic stem cells
Anti-cancer treatments often effectively shrink the size of tumors, but some might have an opposite effect, actually expanding the small population of cancer stem cells believed to drive the disease, according to findings presented today in Atlanta, Georgia at the American Association for Cancer... view more (2007-09-20)
Primrose oil component cuts levels of cancer-causing gene Her-2/neu
Gamma-linolenic acid (GLA), a substance in evening primrose oil and several other plant oils used in herbal medicine, inhibits action of Her-2/neu, a cancer gene that is responsible for almost 30 percent of all breast cancers. view more (2005-11-02)
New treatment for pancreatic cancer allows life-saving surgery
A new treatment for pancreatic cancer developed by clinical researchers of Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center substantially reduces the size of tumors and lowers the risk of local recurrence of the disease. view more (2005-12-07)
Herceptin and chemo improves response rates without major adverse effects in HER2 breast cancer
Women with a particularly aggressive form of breast cancer seem to do better if they are treated with a combined anthracycline and taxane chemotherapy regimen before surgery, together with trastuzumab (Herceptin) before and after surgery, according to results from the largest multi-centre trial to... view more (2008-04-18)
New type of drug shrinks primary breast cancer tumors significantly in just 6 weeks
A drug that targets the cell surface receptors that play an important role in many types of cancer can bring about significant tumour regression in breast cancer after only six weeks of use. view more (2008-04-17)
Potential diagnostic marker indicates effectiveness of anti-angiogenic drugs
If an anti-angiogenic drug is successfully starving a cancer patient's tumor to death, the number of endothelial cells circulating in the individual's bloodstream will decrease, thus providing a potential biomarker for gauging the medication's effectiveness. view more (2006-09-18)
MIT, Brigham: Nanoparticles armed to combat cancer
Ultra-small particles loaded with medicine-and aimed with the precision of a rifle-are offering a promising new way to strike at cancer, according to researchers working at MIT and Brigham and Women's Hospital. view more (2006-04-11)
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