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Sleep attacks from Parkinson`s drugs do exist
Car crashes in patients with Parkinson’s disease have been associated with sudden sleep attacks caused by dopamine drugs, but the concept of sleep attacks, and their connection with dopamine drugs, has been disputed. view more (2002-06-19)
Flies on speed offer insight into the roles of dopamine in sleep and arousal
Methamphetamine, the drug of choice for long-distance truckers and college students pulling all-nighters, appears to do a similar trick for fruit flies, too. This finding is one of several in a new study that demonstrates a critical role for the neurotransmitter dopamine in the modulation of sleep, wake, and arousal states. view more (2005-07-12)
Dopamine study sheds new light on drug addiction
A paper published in today's issue of Science has challenged beliefs about the role of dopamine in the brain, which could lead to new treatments for Parkinson's disease, schizophrenia and drug addiction. The research suggests that dopamine has a far wider, less specialised role than previously hypothesised. view more (2005-03-02)
Phasic firing of dopamine neurons is key to brain's prediction of rewards
Researchers are one step closer to understanding the neurobiology that allows people to successfully learn motivated behaviors by associating environmental cues with rewarding outcomes, according to a study published yesterday in the Proceedings of the National Academy of Sciences' online Early Edition. view more (2009-04-06)
New finding in studying dopamine transporter
Confirming findings in a previous study, Yale researchers observed an altered availability of the dopamine transporter in healthy persons with a genetic variation linked to substance abuse and attention deficit hyperactivity disorder (ADHD). view more (2005-06-07)
1 sleepless night increases dopamine in the human brain
Just one night without sleep can increase the amount of the chemical dopamine in the human brain, according to new imaging research in the August 20 issue of The Journal of Neuroscience. view more (2008-08-20)
Cocaine: Perceived as a reward by the brain?
Cocaine is one of the oldest drugs known to humans, and its abuse has become widespread since the end of the 19th century. view more (2009-05-20)
Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinson's symptoms
New evidence indicates that the loss of two types of brain cells--not just one as previously thought--may trigger the onset of symptoms associated with Parkinson's disease. view more (2007-08-14)
Insulin signaling and amphetamines
Abuse of psychostimulants such as amphetamine remains a serious public health concern. Amphetamines mediate their behavioral effects by stimulating dopaminergic signaling throughout reward circuits of the brain. view more (2007-10-16)
Could hormones explain gender differences in neurological disease?
Neurological diseases including Parkinson's, Tourette's, attention deficit hyperactivity disorder (ADHD), Alzheimer's, and schizophrenia are all associated with alterations in dopamine-driven function involving the dopamine transporter (DAT). view more (2009-06-16)
Risk takers, drug abusers driven by decreased ability to process dopamine
For risk-takers and impulsive people, New Year's resolutions often include being more careful, spending more frugally and cutting back on dangerous behavior, such as drug use. But new research from Vanderbilt finds that these individuals--labeled as novelty seekers by psychologists--face an uphill battle in keeping their New Year's resolutions due... view more... (2008-12-30)
Research links 'ecstasy' to survival of key movement-related cells in brain
New research from the University of Cincinnati (UC) suggests that the widely abused club drug "ecstasy," or MDMA, can increase the survival of dopamine cells in the brain during fetal development. view more (2006-10-19)
New findings show additional similarity between opiate and nicotine addiction
"That was good!" "Do it again." This is what the brain says when people use tobacco, as well as 'hard drugs' such as heroin. view more (2008-02-13)
Depression linked to previously unknown dopamine regulator
Researchers from Harvard Medical School have found a molecule that is unexpectedly involved in dopamine signaling, and in a manner that supports the potential of dopamine as an alternative target for treating depression. view more (2005-07-29)
Caltech scientists engineer supersensitive receptor, gain better understanding of dopamine system
Genetically modifying a receptor found on the neurons that produce the neurotransmitter dopamine has given California Institute of Technology (Caltech) researchers a unique glimpse into the workings of the brain's dopamine system--as well as a new target for treating diseases that result from either too much or too little of this critical... view more... (2008-10-15)
Discovery of post-stimulus activated release implies new mechanisms for dopamine release
The neurotransmitter dopamine continues to be released for nearly an hour after neurons are stimulated, suggesting the existence of secondary mechanisms that allow for sustained availability of dopamine in different regions of the brain including areas critical for memory consolidation, drug induced plasticity and maintaining active networks... view more... (2006-10-16)
Spookiness is in the brain of the beholder
EMBARGOED UNTIL WEDNESDAY 24 JULY 2001 19:00 BST UK CONTACT - Claire Bowles, New Scientist Press Office, London: Tel: +44(0)20 7331 2751 or email claire.bowles@rbi.co.uk WHETHER or not you believe in the paranormal may depend entirely on your brain chemistry. People with high levels of dopamine are more likely to find significance in... view more... (2002-07-24)
Given Up on the New Year's Resolution?
New research reveals why smokers find it so difficult to quit Despite widespread knowledge of the harmful effects of cigarette smoking, nearly 30% of the population still smoke. It can be extremely difficult to stop and fewer than 20% are successful, even with the use of nicotine replacement. The Smoking Research Group at Goldsmiths College,... view more... (2003-01-31)
Cocaine's effects on brain metabolism may contribute to abuse
Many studies on cocaine addiction - and attempts to block its addictiveness - have focused on dopamine transporters, proteins that reabsorb the brain's "reward" chemical once its signal is sent. view more (2008-02-19)
Gene therapy reduces cocaine use in rats
Researchers at the U.S. Department of Energy's Brookhaven National Laboratory have shown that increasing the brain level of receptors for dopamine, a pleasure-related chemical, can reduce use of cocaine by 75 percent in rats trained to self-administer it. view more (2008-04-16)
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