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Dopamine Current Events | Dopamine News | 3

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Unlocking mystery of why dopamine freezes Parkinson's patients
Parkinson's disease and drug addiction are polar opposite diseases, but both depend upon dopamine in the brain. Parkinson's patients don't have enough of it; drug addicts get too much of it. Although the importance of dopamine in these disorders has been well known, the way it works has been a mystery.   view more (2008-08-11)

Medical therapy for restless legs syndrome may trigger compulsive gambling
Compulsive gambling with extreme losses — in two cases, greater than $100,000 — by people without a prior history of gambling problems has been linked to a class of drugs commonly used to treat the neurological disorder restless legs syndrome (RLS).   view more (2007-02-09)

Reward-stress link points to new targets for treating addiction
Rewarding and stressful signals don't seem to have much in common. But researchers studying diseases ranging from drug addiction to anxiety disorders are finding that the brain's reward and stress signaling circuits are intertwined in complex ways.   view more (2008-12-17)

Leptin has powerful effect on reward center in the brain
Leptin, a hormone critical for normal food intake and metabolism, exerts a strong effect on appetite by acting in the mid-brain region as well as in the hypothalamus.   view more (2006-09-29)

Pitt research identifies new target in brain for treating schizophrenia
Research from the University of Pittsburgh could expand the options for controlling schizophrenia by identifying a brain region that responds to more than one type of antipsychotic drug.   view more (2008-11-06)

Lack of motivation in schizophrenia linked to brain chemical imbalance
A study of patients with psychotic illnesses such as schizophrenia suggests an alternative explanation for why many sufferers lack motivation. The research is described today BioMed Central's journal BMC Psychiatry.   view more (2008-05-08)

High Dopamine Transporter Levels Not Correlated with ADHD
Results from a brain-imaging study conducted at the U.S. Department of Energy's Brookhaven National Laboratory in collaboration with Mount Sinai School of Medicine in New York indicate that levels of a brain protein proposed as a diagnostic marker for attention-deficit hyperactivity disorder (ADHD) are not positively correlated with the disease.   view more (2006-11-30)

ISU researchers' findings bring hope for possible Parkinson's disease cure
Researchers at Iowa State University have found an essential key to possibly cure Parkinson's disease and are looking for others.    view more (2009-11-04)

Fine-tuning treatments for depression
New research clarifies how neurotransmitters like norepinephrine, serotonin, and dopamine, are regulated - a finding that may help fine-tune therapies for depression.   view more (2009-10-19)

Brainy robot breaks new ground in Parkinson's research
Researchers at the University of Sheffield have successfully built a 'brain-bot' that could lead to a breakthrough in our understanding of illnesses such as Parkinson's disease, Huntington's disease, schizophrenia and Tourette's syndrome. Brain-bots are robots that are part-controlled by computer models of circuits in the human brain and they can... view more... (2003-04-16)

PET imaging confirms link between receptor levels and cocaine abuse
Using positron emission tomography (PET), researchers have established a firm connection between a particular brain chemistry trait and the tendency of an individual to abuse cocaine and possibly become addicted, suggesting potential treatment options.   view more (2006-07-12)

Dopamine agonist can prevent ovarian hyperstimulation syndrome in IVF patients
A class of drug widely used in a number of gynaecological conditions can prevent ovarian hyperstimulation syndrome (OHSS), an infrequent but serious complication of assisted reproduction treatments.   view more (2006-06-22)

New Target Found to Fight, Treat Parkinson's
Neuroscientists from the University at Buffalo have described for the first time how rotenone, an environmental toxin linked specifically to Parkinson's disease, selectively destroys the neurons that produce dopamine, the neurotransmitter critical to body movement and muscle control.   view more (2005-08-25)

Throwing the micro switch: MicroRNA may link smoking risk gene to neurobiology of addiction
During the past several years, significant progress has been made in identifying susceptibility genes for nicotine dependence through genetic linkage and association analyses.   view more (2009-04-23)

Insulin's brain impact links drugs and diabetes
Insulin, long known as an important regulator of blood glucose levels, now has a newly appreciated role in the brain.   view more (2007-10-17)

Jefferson participating in global study to extend effectiveness of drug for Parkinson's
After Parkinson's disease patients use the drug levodopa or L-dopa for several years as a treatment for restoring the cellular communication that controls muscle movement by replacing lost dopamine, they begin to experience motor complications that include a shortened response to each dose of L-dopa.   view more (2007-04-20)

Meth Promotes Spread of Virus in HIV-Infected Users
Researchers at the University at Buffalo have presented the first evidence that the addictive drug methamphetamine, or meth, also commonly known as "speed" or "crystal," increases production of a docking protein that promotes the spread of the HIV-1 virus in infected users.   view more (2006-08-07)

New research identifies gene important for nicotine's effects on the brain
New research identifies an important gene that influences several aspects of nicotine-induced behaviors in the brain. The study, funded by National Institutes of Drug Abuse, was presented today at the American College of Neuropsychopharmacology's Annual Meeting.   view more (2006-12-06)

Dopamine imbalances cause sleep disorders in animal models of Parkinson's disease and schizophrenia
Neuroscientists at Duke University Medical Center working with genetically engineered mice have found that the brain chemical dopamine plays a critical role in regulating sleep and brain activity associated with dreaming.   view more (2006-10-11)

Key neural system at risk from fetal alcohol exposure
In a study of adult monkeys who were exposed to moderate amounts of alcohol in utero, scientists have found that prenatal exposure to alcohol-even in small doses-has pronounced effects on the development and function later in life of the brain's dopamine system, a critical component of the central nervous system that regulates many regions of the... view more... (2005-09-15)
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