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Cancer cells lose drug resistance following electrical stimulation in vitro
Drug-resistant tumour cells lose their drug resistance when exposed to low intensity, low frequency electric pulses for three days. view more (2006-03-17)
Nanoparticles carry chemotherapy drug deeper into solid tumors
A new drug delivery method using nano-sized molecules to carry the chemotherapy drug doxorubicin to tumors improves the effectiveness of the drug in mice and increases their survival time. view more (2007-06-27)
TARGETED BONE THERAPY COULD IMPROVE SURVIVAL OUTCOME FOR PATIENTS WITH ADVANCED PROSTATE CANCER (pp 326, 336)
Patients responding to chemotherapy for advanced prostate cancer could have increased survival times if specific therapy is targeted at sites of skeletal metastases, concludes research published in this week’s issue of THE LANCET. Prostate cancer tends to spread to the bones, and there is a direct relation between the extent of bone... view more... (2001-01-31)
Potential New Therapeutic Molecular Target to Fight Cancer
Researchers at the Virginia Commonwealth University Massey Cancer Center have identified the enzyme sphingosine kinase 2 as a possible new therapeutic target to improve the efficacy of chemotherapy for colon and breast cancer. view more (2007-11-02)
Synergistic growth inhibitory effect of herbal extracts against HCC and lung cancer cells
Several herbs with diversified pharmacological properties are known to be rich sources of chemical constituents that may have potential for the treatment of several human cancers. Data from the Department of Preclinical Science, Faculty of Medicine, Thammasat University, demonstrates that the growth inhibitory activity of doxorubicin or cisplatin,... view more... (2008-04-30)
Promising new treatment option for women with recurrent ovarian cancer
Combining the new drug trabectedin with pegylated liposomal doxorubicin provides clinical benefit to women with relapsed ovarian cancer, according to new results presented at the 33rd Congress of the European Society for Medical Oncology (ESMO) in Stockholm. view more (2008-09-16)
UCI researchers create new strategy for highly-selective chemotherapy delivery
UC Irvine researchers have created a new approach that vastly improves the targeting of chemotherapeutic drugs to specific cells and organs. view more (2009-09-25)
A search for protection against chemotherapy cardiotoxicity
Researchers at the University of Grenoble, in France, have discovered that erythropoietin administration prevents acute cardiotoxic effects induced by doxorubicin and trastuzumab exposures. view more (2007-12-21)
Genes identified that protect against heart damage from chemotherapy
A series of genes that protect cells from the powerful, common chemotherapeutic agent doxorubicin has been identified by researchers working to understand how the drug also can destroy the heart. view more (2007-12-04)
Avoiding wishful thinking over new drugs - more trials should be double-blinded say cancer experts
Italian researchers have urged that doctors should, wherever possible, be 'blinded' to which drug a patient is receiving in a trial when the endpoint involves subjective judgements by the investigators. They believe it would lessen the risk of wishful thinking - an unconscious tendency by doctors to expect new drugs to perform better than the... view more... (2002-03-11)
Nano-particles Effective in Killing Cancer with One-Two Punch of Chemotherapeutics
Research studies, based at the University of Pennsylvania, demonstrate that biodegradable nano-particles containing two potent cancer-fighting drugs are effective in killing human breast tumors. view more (2006-04-11)
Duke develops nano-scale drug delivery for chemotherapy
Going smaller could bring better results, especially when it comes to cancer-fighting drugs. view more (2009-11-02)
Newer chemotherapies improve outcomes for some types of breast cancer
An updated analysis of findings from three major consecutive clinical trials of breast cancer treatment conducted over the past twenty years indicates that women who have breast cancer with lymph node involvement and estrogen-receptor negative tumors have a lower rate of recurrence and risk of death with treatment with newer chemotherapies. view more (2006-04-12)
CSHL scientists correlate enzyme expression levels with chemotherapy drug response
Why do cancer patients develop resistance to chemotherapy drugs, sometimes abruptly, after a period in which the drugs seem to be working well to reduce tumors or hold them in check? Although largely a mystery to scientists, the result when this occurs is all too familiar: patients relapse and in many cases die when their cancers become resistant. view more (2008-07-21)
Carnegie Mellon scientists develop nanogels that enable controlled delivery of carbohydrate drugs
Carnegie Mellon University scientists have developed tiny, spherical nanogels that uniformly release encapsulated carbohydrate-based drugs. view more (2007-08-21)
Drug combination slows progression of treatment resistant bone marrow cancer
Combining a newly formulated drug with one that is already a standard treatment slows the progression of multiple myeloma, an advanced cancer of the bone marrow cells. view more (2006-12-13)
Safer nanoparticles spotlight tumors, deliver drugs
Small is promising when it comes to illuminating tiny tumors or precisely delivering drugs, but many worry about the safety of nano-scale materials. Now a team of scientists has created miniscule flakes of silicon that glow brightly, last long enough to slowly release cancer drugs, then break down into harmless by-products. view more (2009-02-23)
How chemotherapy drugs block blood vessel growth, slow cancer spread
Researchers at the Johns Hopkins University School of Medicine have discovered how a whole class of commonly used chemotherapy drugs can block cancer growth. view more (2009-01-23)
Not Just for Depression Anymore
Prozac is regularly prescribed to ease the emotional pain of patients who are being treated for cancer. But can this common anti-depressant help to fight cancer itself? view more (2008-12-19)
New technique images tumor vessel leakiness to predict breast cancer chemotherapy outcome
Chemotherapy is an integral part of modern cancer treatment, but it's not always effective. Successful chemotherapy depends on the ability of anticancer drugs to escape from the bloodstream through the leaky blood vessels that often surround tumors. view more (2009-02-02)
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