Drosophila Current Events | Drosophila News
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A balancing act in Parkinson's disease: Phosphorylation of alpha-synuclein
Both genetic and pathologic data indicate a role for the neuronal protein alpha-synuclein in Parkinson disease. view more (2009-10-13)
RNAi and telomere length
A team of Russian scientists, led by Dr. Vladimir Gvozdev (Russian Academy of Sciences) reports on a novel link between RNAi and telomere maintenance in the Drosophila germline. view more (2006-02-01)
Scientists construct a physical map of the Drosophila buzzatii genome
An international team of researchers led by the Universitat Autònoma de Barcelona Professor Alfredo Ruiz, has launched in this month's issue of the journal Genome Research the first detailed physical map of the Drosophila buzzatii chromosomes. view more (2005-06-30)
Xie Lab demonstrates the role of microRNA pathway
Ting Xie, Ph.D., Associate Investigator, and Zhigang Jin, Ph.D., Postdoctoral Research Associate in the Xie Lab, have published results showing that the microRNA pathway is essential for controlling self-renewal of germline stem cells and somatic stem cells in the Drosophila ovary. view more (2007-02-16)
A fly lamin gene is both like and unlike human genes
Lamins are intermediate filament proteins that make up a matrix underlying the nuclear membrane. view more (2007-06-13)
Making sense of antisense microRNAs
Three independent papers in the January 1st issue of G&D report on the discovery of a bidirectionally transcribed microRNA (miRNA) locus in Drosophila. view more (2008-01-02)
First functional insulin-binding protein in invertebrates
Insulin-like growth factor (IGF) signaling that helps to regulate mammals' growth, metabolism, reproduction and longevity is well documented. view more (2008-04-15)
Building brains: Mammalian-like neurogenesis in fruit flies
A new way of generating brain cells has been uncovered in Drosophila. The findings, published this week in the online open access journal Neural Development, reveal that this novel mode of neurogenesis is very similar to that seen in mammalian brains, suggesting that key aspects of neural development could be shared by insects and mammals. view more (2008-02-19)
The clustering of Hox genes, involved in the determination of body segments, is not necessary for their proper function
The Hox genes (also known as homeotic genes) play a crucial role in the development of animals, being involved in the determination of segment identity along the body axis. These genes were discovered in the fruit fly Drosophila melanogaster 90 years ago and have been found later in all animals, including humans. The Hox genes are arranged in the... view more... (2005-05-02)
Cyclacel and MRC geneservice set to distribute Drosophila RNAi set
Cyclacel Limited, the UK-based biopharmaceutical company, announced today that it had entered into an agreement with MRC geneservice for the distribution of its proprietary Drosophila RNA interference (RNAi) collection. This agreement will allow access for MRC geneservice's academic and commercial clients to the Cyclacel collection, for gene... view more... (2003-10-07)
Shilatifard and colleagues identify a potential target for treatment of mixed lineage leukemia
Ali Shilatifard, Ph.D., Investigator, has identified a cellular factor that can reverse histone trimethylation caused by the trithorax gene, the Drosophila homologue of the human mixed lineage leukemia gene, MLL. MLL, which is found in translocations in a variety of hematological malignancies, is a histone H3K4 methyltransferase. view more (2007-03-12)
Obesity genes revealed
A study of 228 women has revealed genetic variants responsible for body shape. Based on work in the fruit fly Drosophila melanogaster, research published today in the open access journal BMC Genetics identifies natural variation in the human LAMA5 gene as a key determinant of weight. view more (2008-08-11)
Fruit fly research may lead to better understanding of human heart disease
Researchers at the Burnham Institute for Medical Research (Burnham) have shown in both fruit flies and humans that genes involved in embryonic heart development are also integral to adult heart function. The study, led by Rolf Bodmer, Ph.D., was published in Proceedings of National Academy of Sciences. view more (2008-12-02)
New species from old data - By searching genome sequences of several Drosophila species researchers have identified new bacterial species that live inside fruit flies.
Researchers have discovered three previously unknown species of a bacterium by scanning a publicly available data bank, reveals a study published today in the journal Genome Biology. The finding highlights the value of making unanalysed data from large-scale genome sequencing projects openly available online. view more (2005-02-18)
A new system for collaboration in cell communication
Investigators from the Institute of Research in Biomedicine (IRB Barcelona) have identified a new signalling mechanism among cells in the fruit fly, Drosophila melanogaster. view more (2007-06-27)
Larvae shun the light
Drosophila larvae avoid light during the foraging stage of their development. Research published in the open access journal BMC Neuroscience shows that both 5-HT (serotonergic) and corazonergic neurons have a role in regulating this behavior. view more (2009-06-23)
A new genetic model for obesity?
A gene involved in fat (lipid) metabolism, and consequently relevant for studies in obesity and diabetes, has been described in Drosophila melanogaster (fruit fly) by a team of researchers in the September issue of Mechanisms of Development. Luis Teixeira and Nathalie F. Vanzo from the European Molecular Biology Laboratory in Heidelberg, Germany,... view more... (2003-09-25)
A reduced arousal threshold in Drosophila mutants prevents them from staying asleep
Most short-sleeping mutant phenotypes in Drosophila (a genus of small flies) are characterized by an inability to stay asleep, most likely because of a reduced arousal threshold, according to a study published in the April 1 issue of the journal SLEEP. view more (2008-04-01)
Fruit flies and global warming - Some like it hot
Researchers working in Australia have discovered ways in which fruit flies might react to extreme fluctuations in temperature. Short-term exposure to high heat stress (heat hardening has been known to have negative effects on Drosophila. view more (2007-01-29)
Fruit flies show how salmonella escapes immune defenses
Salmonella are wily and obnoxious bacterial invaders--escape artists capable of evading multiple immune responses and causing a harsh and debilitating intestinal infection. view more (2008-04-17)
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