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Certain diseases, birth defects may be linked to failure of protein recycling system
A group of signaling proteins known as Wnt - which help build the human body's skin, bone, muscle and other tissues - depend on a complex delivery and recycling system to ensure their transport to tissue-building cell sites, according to a study at Cincinnati Children's Hospital Medical Center. view more (2007-12-21)
Concern that research sponsored by drug companies is biased
Research funded by drug companies is more likely to produce results that favour the sponsor’s product than research funded by other sources, claim researchers in this week’s BMJ. view more (2003-05-28)
Inside job: new radioactive agents for colon cancer work inside cells
Johns Hopkins scientists have developed a potentially novel way to fight colorectal cancer using tiny molecules to deliver potent barrages of radiation inside cancer cells, unlike current treatments that bind to the surface of cells and attack from the outside and cause unwanted side effects. view more (2007-10-10)
Tiny magnets offer breakthrough in gene therapy for cancer
A revolutionary cancer treatment using microscopic magnets to enable 'armed' human cells to target tumours has been developed by researchers funded by the Biotechnology and Biological Sciences Research Council (BBSRC). view more (2008-04-18)
Il-22 gene delivers the goods and decreases intestinal inflammation
There are two major types of inflammatory bowel disease (IBD), Crohn disease (CD) and ulcerative colitis (UC). view more (2008-01-03)
Some masks used in children's asthma treatment not effective, research shows
Some face masks commonly used to help young children inhale asthma medicine are not effective, according to a new study by researchers from Wake Forest University School of Medicine. view more (2006-02-06)
Patience during stalled labor can avoid many c-sections, UCSF study shows
Pregnant women whose labor stalls while in the active phase of childbirth can reduce health risks to themselves and their infants by waiting out the delivery process for an extra two hours, according to a new study by researchers at the University of California, San Francisco. view more (2008-11-03)
Male Injecting-drug Users At Greater Risk Of Drug-related Death (p 941)
A study of injecting-drug users in Scotland in this week's issue of THE LANCET highlights how men-and all injectors over 34 years of age-have the highest drug-related mortality risk. The study also focuses on the need for drug-related deaths to be assessed in relation to the estimated number of injecting-drug users (rather than overall population... view more... (2003-09-17)
Less-toxic drug prolongs survival in metastatic breast cancer
Research from the Northwestern University Feinberg School of Medicine has found that a less toxic, solvent-free chemotherapy drug more effectively prevents the progression of metastatic breast cancer and has fewer side effects than a commonly used solvent-based drug. view more (2009-05-27)
Substance in tree bark could lead to new lung-cancer treatment
Researchers at UT Southwestern Medical Center have determined how a substance derived from the bark of the South American lapacho tree kills certain kinds of cancer cells, findings that also suggest a novel treatment for the most common type of lung cancer. view more (2007-06-26)
atugen AG and metaGen Pharmaceuticals Sign Target Validation Agreement
Berlin, Germany, February 11, 2003 - atugen AG and metaGen Pharmaceuticals GmbH announced today that they have signed an agreement to evaluate the application of atugen's target validation technology in research and development of metaGen's novel cancer drug targets. Under the terms of the agreement atugen will select and screen specially designed... view more... (2003-02-11)
Cognitive behavioural psychotherapy is effective in treating social phobia
In the past decade there has been increasing interest in social phobia, as a disability condition with little spontaneous improvement. Several psychotherapeutic techniques have been shown to be effective. Does the type of psychotherapy matter? It does. For the first time, a sophisticated multicenter randomized controlled French study by Jean... view more... (2000-05-18)
Reanalysis of cigarettes confirms tobacco companies increased addictive nicotine 11 percent
A reanalysis of nicotine yield from major brand name cigarettes sold in Massachusetts from 1997 to 2005 has confirmed that manufacturers have steadily increased the levels of this agent in cigarettes. view more (2007-01-18)
Technology for monitoring fetal oxygen during labor offers no apparent benefit
A new technology for measuring blood oxygen levels of a baby during labor-expected to provide information useful for preventing birth complications-offers no apparent benefit, report researchers in a National Institutes of Health research network. view more (2006-11-27)
CLASSIFICATION OF DRUG-RESISTANT TUBERCULOSIS IS MISLEADING
The traditional clinical classification of types of drug-resistant tuberculosis may be misleading, and could lead to delayed diagnosis and treatment of patients with multidrug-resistant disease, according to a study in this week's issue of The Lancet. Traditionally, patients with drug-resistant tuberculosis are classified as having acquired... view more... (2000-06-28)
Nanoparticles hitchhike on red blood cells: a potential new method for drug delivery
Researchers at the University of California, Santa Barbara have discovered that attaching polymeric nanoparticles to the surface of red blood cells dramatically increases the in vivo lifetime of the nanoparticles. view more (2007-06-27)
Simulated gene therapy
In a recent issue of The Journal of Chemical Physics, published by the American Institute of Physics (AIP), a group of researchers at the University of California, Berkeley and Los Alamos National Laboratory describe the first comprehensive, molecular-level numerical study of gene therapy. view more (2009-04-30)
Carnegie Mellon researchers to develop new drug delivery system
Carnegie Mellon University's Stefan F. Zappe is using adult neural stem cells to develop a new stem cell-based drug delivery therapy that may ultimately help treat a variety of inherited genetic disorders like Hunter syndrome. view more (2007-11-05)
Weekly contact with drug reps linked to unnecessary prescribing
General practitioners who see drug industry representatives at least once a week are more likely to express views that will lead to unnecessary prescribing then those who report less frequent contact, finds a study in this week’s BMJ. view more (2003-05-28)
Radiation costs vary widely by delivery, U-M study finds
When cancer spreads to the bone, radiation treatments can help relieve the pain caused by the tumor. But how best to deliver the radiation may vary widely from one oncologist to the next. view more (2009-10-09)
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