Drug Discovery Current Events | Drug Discovery News | 8
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e-Science methods reveal new insights into antibiotic resistance Large-scale computer simulations have pinpointed a tiny change in molecular structure that could account for drug resistance in Streptomices pneumoniae, the organism that causes childhood pneumonia and claims 3.5 million lives a year, mainly in developing countries. view more (2005-08-16)
Unicellular microRNA discovery In the May 15th issue of Genes & Development, an international collaboration of researchers, led by Dr. Yijun Qi (National Institute of Biological Sciences, China), report on their discovery of microRNAs in the unicellular green alga, Chlamydomonas reinhardtii. This is the first finding of microRNAs in a unicellular organism. view more (2007-04-30)
Plays promote prevention of drug abuse A new study finds that theatrical drama is an educational tool in the fight against drug addiction and abuse. Research published today in Substance Abuse Treatment, Prevention and Policy, shows that after watching the play Tunnels - a series of six vignettes depicting the effects of alcohol and drug abuse - over half of the audience left the... view more... (2007-04-05)
Drug compound leads to death of ovarian cancer cells resistant to chemotherapy In a discovery that may be useful for maintaining remission in chemo-resistant ovarian cancer, Yale scientists report that pre-clinical studies have shown the drug compound NV-128 can induce the death of ovarian cancer cells by halting the activation of a protein pathway called mTOR. view more (2008-04-18)
NTU professor discovers method to efficiently produce less toxic drugs using organic molecules Nanyang Technological University (NTU)'s Associate Professor Zhong Guofu has made a significant contribution to the field of organic chemistry, in particular the study of using small organic molecules as catalysts, in the synthesis process called organocatalysis. view more (2009-07-08)
Better patient outcomes with drug eluting stents Patients receiving drug eluting stents (DES) - stents coated with medication to prevent narrowing of the artery - as part of an angioplasty had better outcomes one year later than patients with bare metal stents, according to a new study to be published in CMAJ http://www.cmaj.ca/press/080050.pdf. view more (2008-12-18)
Enzyme inhibitors block replication Of SARS virus Researchers have known since 2003 that a site on the virus is responsible for mediating proteases that allow the virus to replicate. Since then researchers have been testing protease inhibitors to lock up this site, known as SARS 3CLpro, and effectively stop the virus from infecting additional cells in the body. view more (2006-03-28)
Case Western Reserve University research finds drug candidate slows age-related macular degeneration Research results from the Case Western Reserve University School of Medicine show that the progression of age-related macular degeneration (AMD) is markedly slowed in new laboratory-engineered mice when they received treatments of retinylamine, a trial drug that has been tested in a medical school lab. view more (2008-10-09)
Study of the drug, Isradipine, to determine if it slows or prevents Parkinson's disease Gloria E. Meredith, Ph.D., collaborated with D. James Surmeier, Ph.D. and other scientists at Northwestern University to study the drug, Isradipine, and its possible effects on Parkinson's disease. view more (2007-06-14)
Pitt, US Army team designs new strategy to find drugs to treat neglected infection Using an unconventional approach that they designed, University of Pittsburgh drug discoverers and their collaborators at Walter Reed Army Institute of Research have identified compounds that hold promise for treating leishmaniasis, a parasitic infection that many consider one of the world's most overlooked diseases. view more (2009-11-03)
Researchers find 'surprising link' leads toward a new antibiotic As the best drugs become increasingly resistant to superbugs, McMaster University researchers have discovered a completely different way of looking for a new antibiotic. view more (2009-05-29)
Study links effects of withdrawal to compulsive drug use and craving The study, led by Paul Kenny, Ph.D., an assistant professor at Scripps Research's campus in Jupiter, Florida, and Scott Chen, Ph.D., of the National Institutes of Health Animal Center, appears in the Wednesday, May 31 issue of the Journal of Neuroscience, the official journal of the Society for Neuroscience. view more (2006-06-02)
UCSF research pinpoints brain molecule's role in developing addiction A molecule in the brain essential for wakefulness and appetite has been found to play a central role in strengthening the neuron connections that lead to addiction. view more (2006-02-16)
Researchers discover how antibiotic inhibits bacterial growth Researchers at the University of Illinois at Chicago, in collaboration with research teams from Pharmacia & Upjohn and Pfizer, have discovered precisely how the antibiotic linezolid inhibits bacterial growth. view more (2007-05-11)
Should doctors be 'selling' drugs for the pharmaceutical industry? Are senior doctors who help drug companies sell their drugs independent experts or just drug representatives in disguise, asks Ray Moynihan from the University of Newcastle in Australia, in this week's BMJ. view more (2008-06-20)
LONG-LASTING RESULTS CAN BE OBTAINED WITH PSYCHOTHERAPY IN SOCIAL PHOBIA. Social phobia is a chronic and disabling illness, with little spontaneous improvement. A report by a team of researchers of the Affective Disorders of the University of Bologna, headed by Professor Giovanni Fava, however, sheds a new light on the prognosis of the disorder. In the longest follow-up study published in the literature (2-12 years),... view more... (2001-09-21)
Rapid, Functional, Genome-wide Drug Discovery Enabled Munich, Germany, November 18th, 2003. Xantos Biomedicine AG, a leading functional biology and drug discovery company, announced that it has expanded its collection of full-length human cDNA clones in mammalian expression vectors to 35,000, representing one of the world's largest collections. The Xantos human cDNA collection covers individual cDNA... view more... (2003-11-18)
LONG-LASTING RESULTS CAN BE OBTAINED WITH PSYCHOTHERAPY IN PANIC DISORDER Panic disorder with agoraphobia is a chronic and disabling illness, with little spontaneous improvement. A report by a team of researchers of the Affective Disorders of the University of Bologna, headed by Professor Giovanni Fava, however, sheds a new light on the prognosis of the disorder. In the longest follow-up study published in the... view more... (2001-09-21)
New research shows heroin use falling across Scotland A new report by the Centre for Drug Misuse Research at the University of Glasgow reveals that the number of people misusing heroin in Scotland has dropped. The research shows a near eight per cent drop in the number of problem drug users since 2000. view more (2005-01-19)
Impact of narcotics is greater on mentally ill Narcotics have an irreversible effect on the brains of people already suffering from mental illness. view more (2009-02-06)
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