Drug Discovery Current Events | Drug Discovery News | 9
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The ecstasy and the agony!
New work identifying the attitudes and behaviour of ecstasy users, and possible dangers of ecstasy use, is presented today, Tuesday 19 December, at The British Psychological Society's London Conference, held at the Institute of Education. Dr Phillip Murphy from Edge Hill College of Higher Education, Lancashire presents evidence that ecstasy users... view more... (2000-12-05)
Pitt researchers find candidates for new HIV drugs
While studying an HIV protein that plays an essential role in AIDS progression, researchers at the University of Pittsburgh School of Medicine have discovered compounds that show promise as novel treatments for the disease. view more (2009-10-14)
Drug rescues memory lost to Alzheimer's disease
A drug similar to one used in clinical trials for treatment of rheumatoid arthritis and psoriasis has been found to rescue memory in mice exhibiting Alzheimer's symptoms. view more (2009-07-15)
New drug target in obesity: Fat cells make lots of melanin
As millions of Americans gear up for the Thanksgiving holiday, a new research report published online in The FASEB Journal, may provide some relief for those leery of having a second helping. view more (2008-10-30)
New molecular insight into amboebic dysentery
In the June 15th issue of G&D, Dr. Sinisa Urban (Johns Hopkins University School of Medicine) and colleagues reveal a potential role for the rhomboid enzyme, EhROM1, in the pathogenesis of the enteric protozoan parasite, E. histolytica. view more (2008-06-16)
Could new discovery about a shape-shifting protein lead to a mighty 'morpheein' bacteria fighter?
A small molecule that locks an essential enzyme in an inactive form could one day form the basis of a new class of unbeatable, species-specific antibiotics, according to researchers at Fox Chase Cancer Center. view more (2008-06-23)
ORNL, Protein Discovery researchers collaborate on high-profile paper
A paper that outlines a new method to use a beam of light to trap protein molecules and make them dance in space has earned a place in the Proceedings of the National Academy of Sciences Early Edition. view more (2006-04-13)
Availability of co-proxamol should be restricted
The painkiller co-proxamol is the second most common prescribed drug that people use to commit suicide in England and Wales, and its availability should be restricted, say researchers in this week’s BMJ. view more (2003-05-07)
Innocuous intestinal bacteria may be reservoir for resistance
"Harmless" bacteria in the digestive tracts of dairy cows, may not be so harmless after all. They may be a reservoir for antibiotic resistance genes that can be transferred to more harmful, disease-causing bacteria. view more (2006-05-25)
Criminalising medical mistakes is questionable
Using the criminal justice system to punish doctors who make mistakes is questionable, according to a barrister in this week's BMJ. Citing the case of Feda Mulhem, who was sentenced to eight months in prison after supervising the mistaken injection of a drug into the spine of a teenager with cancer, Jon Holbrook argues that he was not seeking to... view more... (2003-11-11)
Xerion Pharmaceuticals and Arius Research sign colon cancer collaboration
Martinsried, Germany and Cambridge, Massachusetts, USA - October 15, 2002"¦Xerion Pharmaceuticals and ARIUS Research Inc. of Canada announced today that they would combine their respective strengths in functional proteomics and antibody discovery to jointly develop products for cancer therapy. Xerion will take four antibodies from ARIUS'... view more... (2002-10-15)
Drug resistance may travel same path as quorum sensing
The cellular "pumps" associated with multi-drug resistance in bacteria may also be involved in exporting signals responsible for cell-cell communication, a process known as quorum sensing. view more (2006-02-07)
Xantos Biomedicine AG enters the diabetes and obesity therapeutic discovery arena
Collaboration with Professor Hans Hauner provides strong research expertise Xantos Biomedicine AG, a leading functional biology and drug discovery company has announced that it has extended its research activities in metabolic diseases to include a new discovery program for diabetes and obesity. This new therapeutic focus has been further... view more... (2003-09-18)
Wrinkled membranes create novel drug-delivery system
A University of Illinois scientist studying how membranes wrinkle has discovered a novel system for on-demand drug delivery. view more (2006-02-15)
Action needed to avoid HIV drug resistance in Africa
We should stop and think about the risks of resistance, and ways of minimising them, before increasing access to antiretroviral therapy in Africa, argue researchers in this week's BMJ. view more (2004-01-29)
Coercive Sexual Behaviour in British Prisons
New research published in The Howard Journal of Criminal Justice analyses reports of coercive sexual behaviour in British prisons from adult ex-inmates, including both victims and perpetrators. Research, conducted by Dr Samantha Banbury, involved over 400 ex-inmate participants and focused on coercive sexual behaviour including forced drug... view more... (2004-03-11)
New report: The truth about drug innovation
A new report co-authored by Manhattan Institute senior fellow Benjamin Zycher, and Joseph DiMasi, and Christopher-Paul Milne, researchers from the Tufts Center for the Study of Drug Development, examines case histories for thirty-five important pharmaceutical innovations. view more (2008-06-25)
Tentacles of venom: new study reveals all octopuses are venomous
Once thought to be only the realm of the blue-ringed octopus, researchers have now shown that all octopuses and cuttlefish, and some squid are venomous. The work indicates that they all share a common, ancient venomous ancestor and highlights new avenues for drug discovery. view more (2009-04-15)
Stem cell breakthrough: Monitoring the on switch that turns stem cells into muscle
In a genetic engineering breakthrough that could help everyone from bed-ridden patients to elite athletes, a team of American researchers-including 2007 Nobel Prize winner Mario R. Capecchi-have created a "switch" that allows mutations or light signals to be turned on in muscle stem cells to monitor muscle regeneration in a living mammal. view more (2009-03-31)
Enzyme inhibitor takes an unexpected approach toward blocking cancer-promoting protein
Scientists at Fox Chase Cancer Center have discovered a unique method of attack that may be used to inhibit signaling enzymes called kinases, which often have a role in sustaining drug-resistant cancerous cells. They have confirmed that IPA-3, a small molecular inhibitor of a kinase called PAK1, targets the enzyme's regulatory domain, mimicking... view more... (2009-09-08)
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