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Some ethnic groups more susceptible to adverse drug reactions
Some ethnic groups may be more susceptible to adverse drug reactions, finds a study published on bmj.com today.   view more (2006-05-05)

Experts research world-first tests for allergic reactions to medication
It is estimated that up to 10,000 UK hospital patients each year suffer an allergic reaction to anaesthetics, and that one in every 100-200 consumers of penicillin has an allergic response to it. Allergic reactions to fairly common medications generally occur unexpectedly and often within minutes of drug administration, but there are few... view more... (1999-05-24)

Satellite mapping of loa loa prevalence in relation to ivermectin use in west and central Africa (p 1077)
A research letter published in this week's issue of THE LANCET describes a satellite mapping technique in Africa which can identify areas where high loa loa endemicity may adversely affect the safe and effective distribution of ivermectin for the control of river blindness (onchocerciasis). The drug ivermectin has been widely distributed... view more... (2000-09-20)

STUDY HIGHLIGHTS VALUE OF NURSES FOR IDENTIFYING ADVERSE DRUG REACTIONS (p 1345)
Issue 19 April 2003 Embargoed 0001 h (London time) 18 April 2003 Authors of a research letter in this week's issue of THE LANCET highlight the important role that nurses can play in detecting adverse drug reactions (ADR). Policies vary across countries in authorising nurses to report ADR; the UK National Health Service recently expanded the... view more... (2003-04-16)

London School of Hygiene to play key role in global collaboration on adverse drug reactions
The London School of Hygiene & Tropical Medicine is to be a key player in the first global research collaboration aimed at identifying the genetic markers related to Adverse Drug Reactions (ADRs).   view more (2007-09-27)

DNA research taking guesswork out of finding the 'therapeutic window'
It's only spit, but what's inside your saliva may help solve a dosing dilemma facing doctors and patients.   view more (2008-10-24)

Drug-eluting stents may cause allergic reactions
Drug-eluting stents have greatly reduced the risk of repeat blockage of heart arteries, but researchers from Northwestern Memorial Hospital have found that in some patients, the stents can cause allergic reactions that can have serious consequences.   view more (2005-12-20)

Despite No Gender Difference in Adverse Drug Reactions, Women are Treated Less Frequently than Men with Statins, Aspirin and Beta- Blockers
Women and men experience a similar prevalence of adverse drug reactions in the treatment of coronary artery disease; however, women are significantly less likely than their male counterparts to be treated with statins, aspirin, and beta-blockers according to a new study by researchers at Rush University Medical Center.   view more (2008-03-05)

Allergic-like reactions occur in premedicated patients
Allergic-like reactions can occur in patients (both children and adults) when given gadolinium containing contrast agents, even if they have been pre-medicated with corticosteroids and antihistamines, according to a recent study conducted by researchers at the University of Michigan Health Systems in Ann Arbor.   view more (2008-02-11)

The Journal of Clinical Pharmacology looks at effects of smoking cessation drug, varenicline
Smoking is the world's leading cause of premature death. Smokers who quit are able to significantly reduce their risk of premature death and other health issues - almost completely if they quit by age thirty and by fifty percent if they quit after age fifty.   view more (2006-11-01)

Adverse reactions to antibiotics send thousands of patients to the ER
Adverse events from antibiotics cause an estimated 142,000 emergency department visits per year in the United States, according to a study published in the September 15, 2008 issue of Clinical Infectious Diseases.    view more (2008-08-13)

Scientists puzzled by severe allergic reaction to cancer drug in the middle Southern US
A patient's expectations about the side effects of chemotherapy usually focus on nausea, hair loss, fatigue and other side effects. Worries about severe allergic reactions to their therapy is usually not a concern.   view more (2007-08-21)

Desensitization protocol overcomes allergy to clopidogrel
A careful desensitization protocol can help patients overcome allergic reactions to anti-clotting medication critical to preventing new blockages inside coronary stents.   view more (2006-05-12)

Chemical coffee maker promises purer medicines
Their method uses pressurised carbon dioxide as a solvent, because it allows chemical reactions which usually create a mixture of products to produce only one. Project leaders Chris Rayner and Tony Clifford believe it could change the way pharmaceuticals are manufactured in the future. "If the effect is general for a wide range of chemical... view more... (1999-03-15)

Unlicensed and off-label prescribing in children must improve
Many drugs prescribed to children in general practice are either not licensed for use in children ("unlicensed") or are prescribed outside the terms of the product licence ("off-label"). Three studies in this week's BMJ show that unlicensed and off-label prescription of drugs to children is common and carries a high risk of... view more... (2002-05-28)

Newer contrast agents safe for children
Allergic-like reactions to newer iodine-containing contrast agents (nonionic contrast media), are rare in children according to a recent study conducted by researchers from the University of Michigan Medical Center and C.S. Mott Children's Hospital both in Ann Arbor.   view more (2007-06-08)

Only two per cent of child drug trials have independent safety checks
Only two per cent of paediatric drug trials reported using independent safety monitoring committees that can help lead to the early detection of adverse drug reactions, according to a major review published in the journal Acta Paediatrica.   view more (2008-03-19)

Adverse reactions of natural health products/drugs under-reported, study shows
The adverse effects of using prescription drugs side by side with natural health products (NHP) are being under-reported, so the potential risks may be underestimated by health-care professionals and the public.   view more (2007-07-23)

New microchip technology performs 1,000 chemical reactions at once
Flasks, beakers and hot plates may soon be a thing of the past in chemistry labs. Instead of handling a few experiments on a bench top, scientists may simply pop a microchip into a computer and instantly run thousands of chemical reactions, with results - literally shrinking the lab down to the size of a thumbnail.   view more (2009-08-04)

Epilepsy drug may help Alzheimer's patients
A popular epilepsy drug may also be beneficial in patients with Alzheimer's disease (AD), according to a new study to be published on October 27 in the Journal of Experimental Medicine. The anti-seizure drug valproic acid improved memory and reduced brain lesions in mice with an AD-like disease.   view more (2008-10-27)
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